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The map label for this gene is hemA [H]

Identifier: 238026093

GI number: 238026093

Start: 438145

End: 439431

Strand: Reverse

Name: hemA [H]

Synonym: bglu_1g04210

Alternate gene names: 238026093

Gene position: 439431-438145 (Counterclockwise)

Preceding gene: 238026097

Following gene: 238026092

Centisome position: 11.25

GC content: 69.46

Gene sequence:

>1287_bases
ATGCAGCTTCTCACGATCGGAATCAATCACCACACTGCGCCCGTCGCCTTGCGCGAACGCGTAGCGTTTCCGCTCGAACA
GATCAAGCCTGCACTGTCCACGCTGAAGGACGTCTTCCTGGGGCGCCAGGCACGGAACGCGCCCGAGGCGGCGATTCTCT
CCACCTGCAACCGCACCGAGCTCTACTGCGCCACCGACGATCGCGCCGCGCGCGACGCGGCGCTGCGCTGGCTGGCCGAC
TTCCACCGCATCCCGGCCGACGAACTGGCCCCGCACGTCTACGCGCTGCCGCAGTCCGAAGCCGTGCGCCACGCGTTCCG
GGTCGCCTCCGGGCTCGACTCGATGGTGCTCGGCGAAACCCAGATCGTCGGCCAGATGAAGGATGCGGTGCGCACCGCCT
CGGAGGCCGGCGCGCTCGGCACCTATCTGAACCAGCTGTTCCAGCGCACCTTCGCGGTGGCCAAGGAAGTGCGCAGCACC
ACCGAGATCGGTGCGCAGTCGGTGTCGATGGCCGCGGCCGCGGTGCGGCTCGCACAGCGCATCTTCGAGAACGTGGCCGA
CCAGAAGGTGCTGTTCATCGGCGCGGGCGAGATGATCGAGCTCTGCGCGACGCACTTCGCCGCGCAAACGCCGCGCGAGC
TGGTGGTCGCCAACCGCACCGCCGAGCGCGGCGCGAAGCTCGCCGAGCGGTTCGGCGGCCACGCGATGCCGCTCGCGGAC
CTGCCCGCCCGCATGCACGAGTTCGACATCATCGTCTCGTGTACCGCCTCGACGCTGCCGATCATCGGCCTGGGCGCGGT
GGAGCGCGCGGTGAAGGCGCGCCGCCGCCGGCCGATCTTCATGGTCGATCTGGCCGTGCCGCGCGACATCGAGCAGGAGG
TCGGCAAGCTGAAGGACGTGTTCCTCTATACCGTCGACGATCTCGGCGCGATCGTGCGCGAAGGCAGCGCGTCGCGGCAG
GCCGCCGTGGCGCAGGCCGAGACCATCATCGAGACGCGCGTGCAGCACTTCATGCAGTGGCTCGACACGCGCAGCGTGGT
GCCGATCATCCGCCACATGCATACGCAGGCCGACGCGCTGCGCCGCACCGAGGTCGAGCGCGCGCAGAAGATGCTCGCGC
GCGGCGACGATCCGCTCGCCGTGCTCGACGCGCTGTCGCAGGCGCTCACCAACAAGCTGATCCACGGCCCGACCTCGGCG
CTGAACCGCACCAGCGGCACCGAACGCGACCAGTTGATCGACCTGATGCGCGGCTTCTACGCGCATGGCCCGCGCGCCGA
CAACTAG

Upstream 100 bases:

>100_bases
CGCGCGGGATGCGCCGGCGGCCCGGCGGGTCGGCAGCATGGCCGGCAGTGGGAGCAGCGGTAAGACGCTATAATGCGAAC
CTAAACGATAGTCCCCGGAT

Downstream 100 bases:

>100_bases
CGCCGCTGCGCCTTCGGCCGCAGTGCCGGCCCTCCCCCTTTTTCCTTTCGATTCCTCGCCCGGGAGCATCGCTCCAGATC
ATGAAAACGAGCATGCAAAG

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTLKDVFLGRQARNAPEAAILSTCNRTELYCATDDRAARDAALRWLAD
FHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQIVGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRST
TEIGAQSVSMAAAAVRLAQRIFENVADQKVLFIGAGEMIELCATHFAAQTPRELVVANRTAERGAKLAERFGGHAMPLAD
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRRRPIFMVDLAVPRDIEQEVGKLKDVFLYTVDDLGAIVREGSASRQ
AAVAQAETIIETRVQHFMQWLDTRSVVPIIRHMHTQADALRRTEVERAQKMLARGDDPLAVLDALSQALTNKLIHGPTSA
LNRTSGTERDQLIDLMRGFYAHGPRADN

Sequences:

>Translated_428_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTLKDVFLGRQARNAPEAAILSTCNRTELYCATDDRAARDAALRWLAD
FHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQIVGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRST
TEIGAQSVSMAAAAVRLAQRIFENVADQKVLFIGAGEMIELCATHFAAQTPRELVVANRTAERGAKLAERFGGHAMPLAD
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRRRPIFMVDLAVPRDIEQEVGKLKDVFLYTVDDLGAIVREGSASRQ
AAVAQAETIIETRVQHFMQWLDTRSVVPIIRHMHTQADALRRTEVERAQKMLARGDDPLAVLDALSQALTNKLIHGPTSA
LNRTSGTERDQLIDLMRGFYAHGPRADN
>Mature_428_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTLKDVFLGRQARNAPEAAILSTCNRTELYCATDDRAARDAALRWLAD
FHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQIVGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRST
TEIGAQSVSMAAAAVRLAQRIFENVADQKVLFIGAGEMIELCATHFAAQTPRELVVANRTAERGAKLAERFGGHAMPLAD
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRRRPIFMVDLAVPRDIEQEVGKLKDVFLYTVDDLGAIVREGSASRQ
AAVAQAETIIETRVQHFMQWLDTRSVVPIIRHMHTQADALRRTEVERAQKMLARGDDPLAVLDALSQALTNKLIHGPTSA
LNRTSGTERDQLIDLMRGFYAHGPRADN

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=420, Percent_Identity=43.3333333333333, Blast_Score=339, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 47000; Mature: 47000

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTLKDVFLGRQARNAPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHCCCCCE
LYCATDDRAARDAALRWLADFHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCEEECCCHHHHHHHHHHHHCCHHHHHCHH
QIVGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRSTTEIGAQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFENVADQKVLFIGAGEMIELCATHFAAQTPRELVVANRTAERGAKLAERFGGHAMPLAD
HHHHHCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHH
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRRRPIFMVDLAVPRDIEQEVGKLKDV
HHHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHH
FLYTVDDLGAIVREGSASRQAAVAQAETIIETRVQHFMQWLDTRSVVPIIRHMHTQADAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RRTEVERAQKMLARGDDPLAVLDALSQALTNKLIHGPTSALNRTSGTERDQLIDLMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHH
AHGPRADN
HCCCCCCC
>Mature Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTLKDVFLGRQARNAPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHCCCCCE
LYCATDDRAARDAALRWLADFHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCEEECCCHHHHHHHHHHHHCCHHHHHCHH
QIVGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRSTTEIGAQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFENVADQKVLFIGAGEMIELCATHFAAQTPRELVVANRTAERGAKLAERFGGHAMPLAD
HHHHHCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHH
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRRRPIFMVDLAVPRDIEQEVGKLKDV
HHHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHH
FLYTVDDLGAIVREGSASRQAAVAQAETIIETRVQHFMQWLDTRSVVPIIRHMHTQADAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RRTEVERAQKMLARGDDPLAVLDALSQALTNKLIHGPTSALNRTSGTERDQLIDLMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHH
AHGPRADN
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA