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The map label for this gene is mlaA [H]

Identifier: 238025997

GI number: 238025997

Start: 344299

End: 345285

Strand: Direct

Name: mlaA [H]

Synonym: bglu_1g03230

Alternate gene names: 238025997

Gene position: 344299-345285 (Clockwise)

Preceding gene: 238025996

Following gene: 238025998

Centisome position: 8.81

GC content: 69.71

Gene sequence:

>987_bases
ATGCAGACCATGCGCCTCAGGAACGCGGGCTTGACCGTAGCGGCAGTTGCCGCGCTGAGCGGTTGCGCCACCGTTCAGAC
GCCCACCAAGGGCGATCCGTTCGAAAGCTTCAATCGAACGATCTACAAGTTCAACGACACCGTCGACACCTATGCGTTGA
AGCCCGTCGCCCAGGGCTACCAATGGGCGGTGCCGCAGCCGGTGCGCAGCAGCGTGACGAACTTCTTCTCGAACATCGGC
GACGTCTACATCGCCGCCAACAACCTCGTGCAGCTGCGCATCGCCGACGGCGTGGGCGACATCATGCGCGTGGTGATCAA
CACGGTGTTCGGCGTGGGCGGCCTGTTCGACGTGGCGACGGTGGCGAAGCTGCCCAAGCACAGCAACGACTTCGGCATCA
CGCTCGGCCACTACGGCGTGCCATCCGGCCCGTACGTGGTGCTGCCGTTCCTCGGGCCGAGCACGGTGCGCGACACGGCC
GGCCTCGGGGTCGACTACGTCGGCAACCCGCTCACCTGGGTGAATTCGGACGCGGTGAGCTGGAGCCTGTTCGGCGTGAA
CCTGATCAATACGCGCGCGAACCTGCTCGGCGCCGGCGACATCCTCGACGCGGCCGCGATCGACAAGTACTCGTTCGTGC
GCAACGCCTACCTGCAGCGCCGCCAGTCGCTGATCGCCGCCTCGGGCGGCCCCGGCGGCAAGGCGGCCGCCGCGAACGTG
CCCGACTACGGCGCCGAGGCGCTGCCGAAGTACGATCTGCCCGAAGACGGCGCGGCGCCGGCGGCCGCGGCGAGCAGCAC
GGCAGCGGGCGGTGCGGCAGCGGGCGCGGCGGCGCCGGCCCAGGATGCCGCTTCGGCGGCTTCGGCGCCGGCCGCGGCGT
CGGCTGCGGCCATGCCGAATCCGGCCAGTGCCACCCACGTGCCGGCGCAGAACATCGTGCCGCCCTCGCCGAACGGTTTT
CATTGGCCGAGCCTGCGGCTGCGCTGA

Upstream 100 bases:

>100_bases
AAGCCGGCCGCGGCGCCGGGGGCGGCCGCCCATTGAGCGCTCGCGCCGTCCCCGCCGGCGAGGCACCAGACGAAGAAAAG
AGAAAATAGGGAACACGATC

Downstream 100 bases:

>100_bases
TCGCGCCGCGGCCGTTACAGCCGGAAACGTTTGTGACGGCGGCGGATGCAGCATGAAGTCCGCCGCTGGTTCAAAATGCA
GTACCGACTCACTTCGCAGG

Product: VacJ-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MQTMRLRNAGLTVAAVAALSGCATVQTPTKGDPFESFNRTIYKFNDTVDTYALKPVAQGYQWAVPQPVRSSVTNFFSNIG
DVYIAANNLVQLRIADGVGDIMRVVINTVFGVGGLFDVATVAKLPKHSNDFGITLGHYGVPSGPYVVLPFLGPSTVRDTA
GLGVDYVGNPLTWVNSDAVSWSLFGVNLINTRANLLGAGDILDAAAIDKYSFVRNAYLQRRQSLIAASGGPGGKAAAANV
PDYGAEALPKYDLPEDGAAPAAAASSTAAGGAAAGAAAPAQDAASAASAPAAASAAAMPNPASATHVPAQNIVPPSPNGF
HWPSLRLR

Sequences:

>Translated_328_residues
MQTMRLRNAGLTVAAVAALSGCATVQTPTKGDPFESFNRTIYKFNDTVDTYALKPVAQGYQWAVPQPVRSSVTNFFSNIG
DVYIAANNLVQLRIADGVGDIMRVVINTVFGVGGLFDVATVAKLPKHSNDFGITLGHYGVPSGPYVVLPFLGPSTVRDTA
GLGVDYVGNPLTWVNSDAVSWSLFGVNLINTRANLLGAGDILDAAAIDKYSFVRNAYLQRRQSLIAASGGPGGKAAAANV
PDYGAEALPKYDLPEDGAAPAAAASSTAAGGAAAGAAAPAQDAASAASAPAAASAAAMPNPASATHVPAQNIVPPSPNGF
HWPSLRLR
>Mature_328_residues
MQTMRLRNAGLTVAAVAALSGCATVQTPTKGDPFESFNRTIYKFNDTVDTYALKPVAQGYQWAVPQPVRSSVTNFFSNIG
DVYIAANNLVQLRIADGVGDIMRVVINTVFGVGGLFDVATVAKLPKHSNDFGITLGHYGVPSGPYVVLPFLGPSTVRDTA
GLGVDYVGNPLTWVNSDAVSWSLFGVNLINTRANLLGAGDILDAAAIDKYSFVRNAYLQRRQSLIAASGGPGGKAAAANV
PDYGAEALPKYDLPEDGAAPAAAASSTAAGGAAAGAAAPAQDAASAASAPAAASAAAMPNPASATHVPAQNIVPPSPNGF
HWPSLRLR

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=257, Percent_Identity=37.7431906614786, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 33638; Mature: 33638

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTMRLRNAGLTVAAVAALSGCATVQTPTKGDPFESFNRTIYKFNDTVDTYALKPVAQGY
CCCCEECCCCCHHHHHHHHHCCCEECCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHCCC
QWAVPQPVRSSVTNFFSNIGDVYIAANNLVQLRIADGVGDIMRVVINTVFGVGGLFDVAT
CCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
VAKLPKHSNDFGITLGHYGVPSGPYVVLPFLGPSTVRDTAGLGVDYVGNPLTWVNSDAVS
HHHCCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCEEECCCCEE
WSLFGVNLINTRANLLGAGDILDAAAIDKYSFVRNAYLQRRQSLIAASGGPGGKAAAANV
EEEEEEEEECCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCC
PDYGAEALPKYDLPEDGAAPAAAASSTAAGGAAAGAAAPAQDAASAASAPAAASAAAMPN
CCCCHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHCCCC
PASATHVPAQNIVPPSPNGFHWPSLRLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTMRLRNAGLTVAAVAALSGCATVQTPTKGDPFESFNRTIYKFNDTVDTYALKPVAQGY
CCCCEECCCCCHHHHHHHHHCCCEECCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHCCC
QWAVPQPVRSSVTNFFSNIGDVYIAANNLVQLRIADGVGDIMRVVINTVFGVGGLFDVAT
CCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
VAKLPKHSNDFGITLGHYGVPSGPYVVLPFLGPSTVRDTAGLGVDYVGNPLTWVNSDAVS
HHHCCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCEEECCCCEE
WSLFGVNLINTRANLLGAGDILDAAAIDKYSFVRNAYLQRRQSLIAASGGPGGKAAAANV
EEEEEEEEECCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCC
PDYGAEALPKYDLPEDGAAPAAAASSTAAGGAAAGAAAPAQDAASAASAPAAASAAAMPN
CCCCHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHCCCC
PASATHVPAQNIVPPSPNGFHWPSLRLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]