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The map label for this gene is mlaC [H]

Identifier: 238025998

GI number: 238025998

Start: 345393

End: 346019

Strand: Direct

Name: mlaC [H]

Synonym: bglu_1g03240

Alternate gene names: 238025998

Gene position: 345393-346019 (Clockwise)

Preceding gene: 238025997

Following gene: 238025999

Centisome position: 8.84

GC content: 62.84

Gene sequence:

>627_bases
ATGAAAAAACTGTTTCTGATTCCCGTGGTAGCCGCGTTTTTCTCGTTTGGTAGCGCCGCCTACGCGCAGGTCGACCAGTC
GAACCCGCAGGCGCTCATCAAGACCGCGACCGAGCAGGTGATGAACGAGGTCCGGACGCAGTCGATCAAGCCGGGCGACA
TCGGCAGGATTACCGATATCGTGAATCGCGATATCCTCCCGTACACCGATTTCCGCCGCACCACGCAGCTCGTGATGGGC
CGCAACTGGCGCGCCGCGACGCCCGACCAACGCGACAAGGTGGTCGAACAGTTCAAGATGCTGCTGATCCGCACCTACTC
CGGCGCGATCGCGCAGCTGAAGGCCGACCAGCAGATTCAGTACCTGCCGTTCCGCGCCGATCCGGGCGCAACCGACGTGG
TGGTGCGCACGCTCGCCTCGAACAACGGCCAGCCGGTGCAGATCGACTACCGTCTCTACAAGACGCCGCAGGGCTGGCGC
GTCTATGACCTGAACGTGCTCGGCGCCTGGCTGATCCAGACCTACCAGCAGCAGTTCAACGAGAAGATCCAGCAGAGCGG
CGTGGACGGCCTGATCCAGTTCCTCACGCAGCGCAACGAGCAGCTCGCTGCCGGCAAGGCATCGTGA

Upstream 100 bases:

>100_bases
GCGGCCGTTACAGCCGGAAACGTTTGTGACGGCGGCGGATGCAGCATGAAGTCCGCCGCTGGTTCAAAATGCAGTACCGA
CTCACTTCGCAGGACATCTC

Downstream 100 bases:

>100_bases
GCCAGTTCGCCACCGGCGCCTCGCTGACCTACGCGAGCGCGAAGGCCGCGCTCGACGACGGGCTCGGCCGCATCGCCGGC
GGCGCGACCGCGGTGGACTG

Product: toluene tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKLFLIPVVAAFFSFGSAAYAQVDQSNPQALIKTATEQVMNEVRTQSIKPGDIGRITDIVNRDILPYTDFRRTTQLVMG
RNWRAATPDQRDKVVEQFKMLLIRTYSGAIAQLKADQQIQYLPFRADPGATDVVVRTLASNNGQPVQIDYRLYKTPQGWR
VYDLNVLGAWLIQTYQQQFNEKIQQSGVDGLIQFLTQRNEQLAAGKAS

Sequences:

>Translated_208_residues
MKKLFLIPVVAAFFSFGSAAYAQVDQSNPQALIKTATEQVMNEVRTQSIKPGDIGRITDIVNRDILPYTDFRRTTQLVMG
RNWRAATPDQRDKVVEQFKMLLIRTYSGAIAQLKADQQIQYLPFRADPGATDVVVRTLASNNGQPVQIDYRLYKTPQGWR
VYDLNVLGAWLIQTYQQQFNEKIQQSGVDGLIQFLTQRNEQLAAGKAS
>Mature_208_residues
MKKLFLIPVVAAFFSFGSAAYAQVDQSNPQALIKTATEQVMNEVRTQSIKPGDIGRITDIVNRDILPYTDFRRTTQLVMG
RNWRAATPDQRDKVVEQFKMLLIRTYSGAIAQLKADQQIQYLPFRADPGATDVVVRTLASNNGQPVQIDYRLYKTPQGWR
VYDLNVLGAWLIQTYQQQFNEKIQQSGVDGLIQFLTQRNEQLAAGKAS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=206, Percent_Identity=28.1553398058252, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23559; Mature: 23559

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFLIPVVAAFFSFGSAAYAQVDQSNPQALIKTATEQVMNEVRTQSIKPGDIGRITDI
CCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VNRDILPYTDFRRTTQLVMGRNWRAATPDQRDKVVEQFKMLLIRTYSGAIAQLKADQQIQ
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEE
YLPFRADPGATDVVVRTLASNNGQPVQIDYRLYKTPQGWRVYDLNVLGAWLIQTYQQQFN
EECCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHH
EKIQQSGVDGLIQFLTQRNEQLAAGKAS
HHHHHCCHHHHHHHHHHCCHHHCCCCCC
>Mature Secondary Structure
MKKLFLIPVVAAFFSFGSAAYAQVDQSNPQALIKTATEQVMNEVRTQSIKPGDIGRITDI
CCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VNRDILPYTDFRRTTQLVMGRNWRAATPDQRDKVVEQFKMLLIRTYSGAIAQLKADQQIQ
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEE
YLPFRADPGATDVVVRTLASNNGQPVQIDYRLYKTPQGWRVYDLNVLGAWLIQTYQQQFN
EECCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHH
EKIQQSGVDGLIQFLTQRNEQLAAGKAS
HHHHHCCHHHHHHHHHHCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]