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The map label for this gene is acoC [H]

Identifier: 339717978

GI number: 339717978

Start: 2166428

End: 2167468

Strand: Direct

Name: acoC [H]

Synonym: NA

Alternate gene names: 339717978

Gene position: 2166428-2167468 (Clockwise)

Preceding gene: 238025071

Following gene: 238025074

Centisome position: 76.62

GC content: 71.47

Gene sequence:

>1041_bases
GTGAACATCATGATCGTCCAACTGATCGCCGTCGTGCTTGCCCTCTATGCCGTGCTGTTCGCGTTTACGCTGTTCACCGC
CCATCAGGTGCGCCGCCGCTTTCCGCCCGAGGGCAAGTTCGTCGAGATCGACGGCGACCGCCTGCATTACGTCGAATACG
GCAGCGGCCCGCCGATCGTGATGGTGCATGGCCTGTGCGGGCAACTGCGCAACTTCGTCTACCTGGACCTGGCGCGGCTC
GCCCAATCGCATCGCGTGATCCTCGTCGATCGGGCCGGCTCGGGGCGCTCGACGCGCGGCCCCGGCTCGCGCGCGAACGT
CTACGCGCAGGCCCGCAGCATCGCACGCTTCATCGAGACGCTCGGCCTCGAGCGGCCCGTGCTGGTGGGCCATTCGCTCG
GCGGCGCGATCGCGCTCGCGGTCGGCCTCGACTACCCGGAACGCGTGAGCCGCATCGCGCTGATCGCGCCGCTCACGCAC
ACCGAGACGGCGCCGCCCAAGGCGTTCCGCGGGCTCGCGCTGCGCCCGGCGGCGCTGCGCCGCTTCGCGTCGCTGACGAT
GGGCATTCCGATCATGATCCTGCAAAGCCGCAAGGCGATCGACGCGATCTTCGCGCCCGAACCGGTGCCGCGCGATTTTC
CGCTGAAGGGCGGCGGCCTGATGGGGCTGCGGCCCGAGGCGTTCTACGCGGCCTCGTCGGACTTGGTCGCCGCGCCCGAG
GATCTGCCCGACATGGAGCGGCGCTATCCCACGCTCGGCGTGCCGGTCAGCATGCTCTACGGGCGCCAGGATGCGATCCT
CGATTTCCACAAGCACGGCGAGGGTCTCAAGCACAAGCTTGGCAGCGTCGAGCTGAGGGCCGTCGACGGCGGCCACATGC
TGCCCGTCACGCAGCCCGGCGCGACCACCGACTGGCTGCTCGCGGTGGCCGCGGCGGCCGCCGCGCCGCAGCCCGACGCG
GCACGGCCGGAACCGGCGCCGTCCGAGCTCGTGCGGGGCGGCACCGCGCAGCCGGCCGTGCGCCTCGCCACCGGGCGCTG
A

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: esterase EstD

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system; Fast-migrating protein; FMP [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:
NA

Sequences:

>Translated_346_residues
MNIMIVQLIAVVLALYAVLFAFTLFTAHQVRRRFPPEGKFVEIDGDRLHYVEYGSGPPIVMVHGLCGQLRNFVYLDLARL
AQSHRVILVDRAGSGRSTRGPGSRANVYAQARSIARFIETLGLERPVLVGHSLGGAIALAVGLDYPERVSRIALIAPLTH
TETAPPKAFRGLALRPAALRRFASLTMGIPIMILQSRKAIDAIFAPEPVPRDFPLKGGGLMGLRPEAFYAASSDLVAAPE
DLPDMERRYPTLGVPVSMLYGRQDAILDFHKHGEGLKHKLGSVELRAVDGGHMLPVTQPGATTDWLLAVAAAAAAPQPDA
ARPEPAPSELVRGGTAQPAVRLATGR
>Mature_346_residues
MNIMIVQLIAVVLALYAVLFAFTLFTAHQVRRRFPPEGKFVEIDGDRLHYVEYGSGPPIVMVHGLCGQLRNFVYLDLARL
AQSHRVILVDRAGSGRSTRGPGSRANVYAQARSIARFIETLGLERPVLVGHSLGGAIALAVGLDYPERVSRIALIAPLTH
TETAPPKAFRGLALRPAALRRFASLTMGIPIMILQSRKAIDAIFAPEPVPRDFPLKGGGLMGLRPEAFYAASSDLVAAPE
DLPDMERRYPTLGVPVSMLYGRQDAILDFHKHGEGLKHKLGSVELRAVDGGHMLPVTQPGATTDWLLAVAAAAAAPQPDA
ARPEPAPSELVRGGTAQPAVRLATGR

Specific function: Dihydrolipoamide acetyltransferase involved in acetoin catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=109, Percent_Identity=34.8623853211009, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 37212; Mature: 37212

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIMIVQLIAVVLALYAVLFAFTLFTAHQVRRRFPPEGKFVEIDGDRLHYVEYGSGPPIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCCCCEE
MVHGLCGQLRNFVYLDLARLAQSHRVILVDRAGSGRSTRGPGSRANVYAQARSIARFIET
EECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGLERPVLVGHSLGGAIALAVGLDYPERVSRIALIAPLTHTETAPPKAFRGLALRPAALR
HCCCCCEEEECCCCCEEEEEECCCCHHHHHHEEEEECCCCCCCCCCHHHHCCCCCHHHHH
RFASLTMGIPIMILQSRKAIDAIFAPEPVPRDFPLKGGGLMGLRPEAFYAASSDLVAAPE
HHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEECCC
DLPDMERRYPTLGVPVSMLYGRQDAILDFHKHGEGLKHKLGSVELRAVDGGHMLPVTQPG
CCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCCHHHHCCCCEEEEEECCCEEEEECCCC
ATTDWLLAVAAAAAAPQPDAARPEPAPSELVRGGTAQPAVRLATGR
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCC
>Mature Secondary Structure
MNIMIVQLIAVVLALYAVLFAFTLFTAHQVRRRFPPEGKFVEIDGDRLHYVEYGSGPPIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCCCCEE
MVHGLCGQLRNFVYLDLARLAQSHRVILVDRAGSGRSTRGPGSRANVYAQARSIARFIET
EECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGLERPVLVGHSLGGAIALAVGLDYPERVSRIALIAPLTHTETAPPKAFRGLALRPAALR
HCCCCCEEEECCCCCEEEEEECCCCHHHHHHEEEEECCCCCCCCCCHHHHCCCCCHHHHH
RFASLTMGIPIMILQSRKAIDAIFAPEPVPRDFPLKGGGLMGLRPEAFYAASSDLVAAPE
HHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEECCC
DLPDMERRYPTLGVPVSMLYGRQDAILDFHKHGEGLKHKLGSVELRAVDGGHMLPVTQPG
CCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCCHHHHCCCCEEEEEECCCEEEEECCCC
ATTDWLLAVAAAAAAPQPDAARPEPAPSELVRGGTAQPAVRLATGR
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2061286 [H]