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The map label for this gene is resE [H]

Identifier: 238025557

GI number: 238025557

Start: 2795699

End: 2797528

Strand: Direct

Name: resE [H]

Synonym: bglu_2g22540

Alternate gene names: 238025557

Gene position: 2795699-2797528 (Clockwise)

Preceding gene: 238025539

Following gene: 238025558

Centisome position: 98.88

GC content: 74.21

Gene sequence:

>1830_bases
ATGACCGATCCGATCACGCTCACCGCACCCGACAATCCGCTGCATGTGCTCGTCGTCGACGATATCGGCGCGAGCCGCGC
GGAAACCGCCTCGCAGGTCCGCGCGGCCGGCCACCACGTGATCGAGGCCGACAGCGGCCGCGCCGCGCTCGCCGTGGTGG
AGACCACCGCCGTCGACCTCGTGCTGCTCGACCTGCTGATGCCCGACATGGACGGCTTCGAGGCCACGCGCCGCCTGCGC
GCGAGCCACGAGCGCGCCTGGCTGCCGATCGTGGTGATGTCCTCGCTGCACGGCGCCGAGCATTTCGTGCGCGCCGTGGA
GGAAGGTGCCGACGACTATCTCGTCAAGCCCGTGGACGGCGCGCTGCTGGCCGCGAAGATCCGCAACATCGGCCACGTGC
TCGACCTGCAGTCGCGCGTGGCCAGTCTCGCGGCGCACAATCGCGAACTGTTCGACCACGTCGGCGACGCGGTGCTGACG
ATCGAGGACGGCACGCGCATCTGCGACGCCAACGCGGCCGGCTATGCGCTGCTCGGCCTCGACGCGCTGCCCGCCGGCGG
TGCGCCGCTCGACGCGCTGCTGCCCGCCGAGCTGTCCGAGCGGCTGCGCGCCGACACGCCGCCCGCCGCCTGCCAGGCGC
TGGTGCGCGGCCCGTCGGGCGACACCTTTCCGGCCGACATCCGCATCAGCCGCTGGCGCAACAGCGCACTGCCGCGCGTG
TCGCTGGTGATCCGCGATCTCACCGAGCAGCGCCGGCTGGACCGCCTCAAGGACGATTTCCTCAGCACCGTCAGCCACGA
GCTGCGCACCCCGCTCACCTCGGTGAAGGGCGCCGTGGACCTGCTCGCGGGCGGCGCGGCCGGCGCGCTGCCCGCGCCGG
CGCAGAAGCTGGTCGATATCGCGCGGCGCAACGGCGAGCGGCTCGGCCGGCTGATCGACGACGTGCTCGACGTCGCCAAG
CTCGAGGCCGACCGCATGACGCTGCAGCGCCGCGCCTGCGGGCTGGACGGGCTGGTCGACGAGGCGCTCGCGGCCAACCT
CGACTATGCGCGGCGGGTGGGCGTGCACCTCACGCGCGTCGGCGCGCGCTTCGATTGCGAGGTGTGGGTCGACCCCGACC
GCTTCCTGCAGGTGATGGCGAACCTGCTGTCGAACGCCATCAAGAACTCGCCGGCCGGCAGCGCGGTGGAGGTCCGCGGC
ACGCGCGACGGCGCGCGCGCGCGCATCGCCGTGCGCGACCACGGCGGCGGCATCCCGGAGGCGTTCCGCGCGCGCATCTT
CGAAAAGTTCTCGCAGGCCGACGAGCGCGACCGCCGCGTCGGCACCGGCACCGGGCTCGGCCTGCACATCACGCAGGTGC
TGGTCGAGCGCATGCACGGCGCGGTCGGGGTGGTATCCACGCCGGGCCACGGCGCCGAGTTCCACGTCGACCTGCCGACC
GGCGACGCCGCGGCGGTGCTGCCGCCCACCCGGCCGACCGCGTTCGTGATCGATCCCGACGCGGCGGCGCGCGCGCGGAT
CGCCGCCGCGCTCGCGCCCCGATTCACGCCGCTCACCGCGGCCGATCCCGAGGCCCTCGAGGCCGCCGCGATCACCGCGC
CGGCGCTGGTGGTGGCCGATCCGTCGCGCGGGCGCGACGCCCCCGAGGCCGTGGCCCGCCGGCTGCGAGAAATCGCCGGC
CCCGCGCCGATCCTGCTCTACACTGACGACGTTTCGGCCGCCGCCACGGCGATCGCGGCCGACCGGCTGCCCAAGCGCGG
TACCGACGACGATGCGTTGCTGCGTGCCGCGCGGCGCATCGCCCATCCCGACGGAGGACCCCATCGATGA

Upstream 100 bases:

>100_bases
TGCCGGGTCATCCACGCCTCGCCGCCCGGTGGCATAATCGGCTGGCCATGACTCCTCGCTGCGTGCCGCGTACCCAGCTG
TGCCGGCATGCGCCGCCACG

Downstream 100 bases:

>100_bases
GCACCACGCTGCACCGGGTGTTGTGCGCCGAGGACGACCCGGACATTCGGGCGATCCTCGAATTCAGTCTCGGCGTCGTC
GGCGGCTACGACGTGCGGCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MTDPITLTAPDNPLHVLVVDDIGASRAETASQVRAAGHHVIEADSGRAALAVVETTAVDLVLLDLLMPDMDGFEATRRLR
ASHERAWLPIVVMSSLHGAEHFVRAVEEGADDYLVKPVDGALLAAKIRNIGHVLDLQSRVASLAAHNRELFDHVGDAVLT
IEDGTRICDANAAGYALLGLDALPAGGAPLDALLPAELSERLRADTPPAACQALVRGPSGDTFPADIRISRWRNSALPRV
SLVIRDLTEQRRLDRLKDDFLSTVSHELRTPLTSVKGAVDLLAGGAAGALPAPAQKLVDIARRNGERLGRLIDDVLDVAK
LEADRMTLQRRACGLDGLVDEALAANLDYARRVGVHLTRVGARFDCEVWVDPDRFLQVMANLLSNAIKNSPAGSAVEVRG
TRDGARARIAVRDHGGGIPEAFRARIFEKFSQADERDRRVGTGTGLGLHITQVLVERMHGAVGVVSTPGHGAEFHVDLPT
GDAAAVLPPTRPTAFVIDPDAAARARIAAALAPRFTPLTAADPEALEAAAITAPALVVADPSRGRDAPEAVARRLREIAG
PAPILLYTDDVSAAATAIAADRLPKRGTDDDALLRAARRIAHPDGGPHR

Sequences:

>Translated_609_residues
MTDPITLTAPDNPLHVLVVDDIGASRAETASQVRAAGHHVIEADSGRAALAVVETTAVDLVLLDLLMPDMDGFEATRRLR
ASHERAWLPIVVMSSLHGAEHFVRAVEEGADDYLVKPVDGALLAAKIRNIGHVLDLQSRVASLAAHNRELFDHVGDAVLT
IEDGTRICDANAAGYALLGLDALPAGGAPLDALLPAELSERLRADTPPAACQALVRGPSGDTFPADIRISRWRNSALPRV
SLVIRDLTEQRRLDRLKDDFLSTVSHELRTPLTSVKGAVDLLAGGAAGALPAPAQKLVDIARRNGERLGRLIDDVLDVAK
LEADRMTLQRRACGLDGLVDEALAANLDYARRVGVHLTRVGARFDCEVWVDPDRFLQVMANLLSNAIKNSPAGSAVEVRG
TRDGARARIAVRDHGGGIPEAFRARIFEKFSQADERDRRVGTGTGLGLHITQVLVERMHGAVGVVSTPGHGAEFHVDLPT
GDAAAVLPPTRPTAFVIDPDAAARARIAAALAPRFTPLTAADPEALEAAAITAPALVVADPSRGRDAPEAVARRLREIAG
PAPILLYTDDVSAAATAIAADRLPKRGTDDDALLRAARRIAHPDGGPHR
>Mature_608_residues
TDPITLTAPDNPLHVLVVDDIGASRAETASQVRAAGHHVIEADSGRAALAVVETTAVDLVLLDLLMPDMDGFEATRRLRA
SHERAWLPIVVMSSLHGAEHFVRAVEEGADDYLVKPVDGALLAAKIRNIGHVLDLQSRVASLAAHNRELFDHVGDAVLTI
EDGTRICDANAAGYALLGLDALPAGGAPLDALLPAELSERLRADTPPAACQALVRGPSGDTFPADIRISRWRNSALPRVS
LVIRDLTEQRRLDRLKDDFLSTVSHELRTPLTSVKGAVDLLAGGAAGALPAPAQKLVDIARRNGERLGRLIDDVLDVAKL
EADRMTLQRRACGLDGLVDEALAANLDYARRVGVHLTRVGARFDCEVWVDPDRFLQVMANLLSNAIKNSPAGSAVEVRGT
RDGARARIAVRDHGGGIPEAFRARIFEKFSQADERDRRVGTGTGLGLHITQVLVERMHGAVGVVSTPGHGAEFHVDLPTG
DAAAVLPPTRPTAFVIDPDAAARARIAAALAPRFTPLTAADPEALEAAAITAPALVVADPSRGRDAPEAVARRLREIAGP
APILLYTDDVSAAATAIAADRLPKRGTDDDALLRAARRIAHPDGGPHR

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=37.280701754386, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=35.3909465020576, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=31.25, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=31.0043668122271, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=32.4110671936759, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786600, Length=332, Percent_Identity=28.0120481927711, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=29.8165137614679, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=28.0632411067194, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786783, Length=242, Percent_Identity=26.4462809917355, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788549, Length=359, Percent_Identity=23.1197771587744, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=24.7787610619469, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=357, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786784, Length=135, Percent_Identity=32.5925925925926, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=28.6307053941909, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=109, Percent_Identity=36.697247706422, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787229, Length=124, Percent_Identity=30.6451612903226, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=32.2314049586777, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788550, Length=104, Percent_Identity=33.6538461538462, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64616; Mature: 64485

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPITLTAPDNPLHVLVVDDIGASRAETASQVRAAGHHVIEADSGRAALAVVETTAVDL
CCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEHHHHHHH
VLLDLLMPDMDGFEATRRLRASHERAWLPIVVMSSLHGAEHFVRAVEEGADDYLVKPVDG
HHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCEECCCCC
ALLAAKIRNIGHVLDLQSRVASLAAHNRELFDHVGDAVLTIEDGTRICDANAAGYALLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCEEEEEC
DALPAGGAPLDALLPAELSERLRADTPPAACQALVRGPSGDTFPADIRISRWRNSALPRV
CCCCCCCCCHHHHCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEHHCCCCCCHH
SLVIRDLTEQRRLDRLKDDFLSTVSHELRTPLTSVKGAVDLLAGGAAGALPAPAQKLVDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ARRNGERLGRLIDDVLDVAKLEADRMTLQRRACGLDGLVDEALAANLDYARRVGVHLTRV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCEEEEE
GARFDCEVWVDPDRFLQVMANLLSNAIKNSPAGSAVEVRGTRDGARARIAVRDHGGGIPE
CCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCHH
AFRARIFEKFSQADERDRRVGTGTGLGLHITQVLVERMHGAVGVVSTPGHGAEFHVDLPT
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
GDAAAVLPPTRPTAFVIDPDAAARARIAAALAPRFTPLTAADPEALEAAAITAPALVVAD
CCCEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEC
PSRGRDAPEAVARRLREIAGPAPILLYTDDVSAAATAIAADRLPKRGTDDDALLRAARRI
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHPDGGPHR
CCCCCCCCC
>Mature Secondary Structure 
TDPITLTAPDNPLHVLVVDDIGASRAETASQVRAAGHHVIEADSGRAALAVVETTAVDL
CCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEHHHHHHH
VLLDLLMPDMDGFEATRRLRASHERAWLPIVVMSSLHGAEHFVRAVEEGADDYLVKPVDG
HHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCEECCCCC
ALLAAKIRNIGHVLDLQSRVASLAAHNRELFDHVGDAVLTIEDGTRICDANAAGYALLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCEEEEEC
DALPAGGAPLDALLPAELSERLRADTPPAACQALVRGPSGDTFPADIRISRWRNSALPRV
CCCCCCCCCHHHHCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEHHCCCCCCHH
SLVIRDLTEQRRLDRLKDDFLSTVSHELRTPLTSVKGAVDLLAGGAAGALPAPAQKLVDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ARRNGERLGRLIDDVLDVAKLEADRMTLQRRACGLDGLVDEALAANLDYARRVGVHLTRV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCEEEEE
GARFDCEVWVDPDRFLQVMANLLSNAIKNSPAGSAVEVRGTRDGARARIAVRDHGGGIPE
CCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCHH
AFRARIFEKFSQADERDRRVGTGTGLGLHITQVLVERMHGAVGVVSTPGHGAEFHVDLPT
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
GDAAAVLPPTRPTAFVIDPDAAARARIAAALAPRFTPLTAADPEALEAAAITAPALVVAD
CCCEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEC
PSRGRDAPEAVARRLREIAGPAPILLYTDDVSAAATAIAADRLPKRGTDDDALLRAARRI
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHPDGGPHR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]