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The map label for this gene is mocR [H]

Identifier: 238025105

GI number: 238025105

Start: 2207313

End: 2208803

Strand: Direct

Name: mocR [H]

Synonym: bglu_2g17640

Alternate gene names: 238025105

Gene position: 2207313-2208803 (Clockwise)

Preceding gene: 238025104

Following gene: 238025106

Centisome position: 78.07

GC content: 74.11

Gene sequence:

>1491_bases
ATGGATTACCGTGTCCTGCTCGCGGCGTTCTCGCGCGAGGCCGGCGGCGAGGGTGCCGGCCCGGGCCGGCTCAGCCAGCA
GCACCGCCTGTACGCCAGTCTGCGCGAAGCGATCCTGCGGCGCGCGCTCGACGCGGACACGGCGCTGCCCTCGTCGCGCG
CGCTCGCCGAGACGCTGCGGATCGCACGCAATTCGGTGCTCTACGCCTACGAGCGGCTCGCCGCCGAGGGTTTCGTGGTG
GCGGACCGGCAAGGCACGCGCGTGGCCCGTATGGTGCTGCCGGCCGAGCCCGACGCCGACGCCCCGCTCGCGCCGCCGCC
GCTGTCACGGCGCGCCACCAGCCTCGGCCACTTCTCGGATCGCGCCGGCGAAACCGGGGCGTTCGTGCCCGGCGTGCCGG
CGCTCGATGCGTTCCCGCTCGCGGCGTGGCGGCGCGCGGTCGAACGCGCATGGCGCCGCGTCGGCCCGGCGCAGCTCGAC
TATCAGCCGTCGGCCGGCAACCTGCCGCTGCGCCATGCGATCGTCGACTACCTGCGCGTTTCGCGCGGCGTGGCCTGCGA
CGCGGATCAGGTGCTGATCACCGACGGCACGCAGCATGGCCTCGATCTCTGCGCCCGCGCGCTTGCCGACGCCGGCGACG
TCGCCTGGATCGAGAATCCCGGCTACGGCGGCGCACGCGTCGCGCTACGCGCGGCCGGCTTGCGCCTCGTCCCGGTGCCG
GTGGACGCGCACGGCCTCGCACCGGCACCCGACCTCTGGCGCAGCGCGCCGCCGCGGCTCGTCTACGTCACGCCCTCGCA
CCAATATCCGCTCGGCGCCGTGATGTCGCCCGAGCGGCGCGTCGCGCTGGTGCGGGCCGCGCGCGACGCCGGCGCCTGGA
TCGTCGAGGACGACTACGACAGCGAATTCCGCCATCACGGCACGCCGCTCGCGGCGCTGCAAAGCAGCGTGCGCGATGCG
CCGGTGATCTATCTCGGCACGTTTTCGAAGGTGATGTTCCCGGCGCTGCGGATCGGCTTCGTGGTGGTGCCGGCCGCCAT
CGCAACCGAGCTCGAACGCGTCTCGGCGGCGCTCGCGCCGCGCGGACGCCTGGCCGACCAGCTCGCGCTCGCCGAATTCA
TCGAGGCCGGCCAGTTCACGCGTCACCTGCGCCGCATGCGCCGGCTCTACGCGGAGCGCCGCGACGCGCTGCACGACACG
CTTTCGCGGCGTCTCGGCGGCATGCTGACGGTGTCGGCCGGCGACGGCGGCATGCACCTGTCGGCACGGCTCGACGCCGG
CGTGTCCGACCTCGATGTCTACCGCGCCGGCCGCGCGCACGGCCTGGTGATCCGGCCGCTCTCGCCGTTCTGCGCGCCGG
GCACCGATCCGTCGGCCTACAACGGCCTCGTGCTCGGCTACGGCAGCGTCGCCGTCGAGTCGATGGACGATGCCGTGATC
CGGCTCGAGCGCGCGATCGGGGATGCACATCGCGCGCGGCGCGCATCCTGA

Upstream 100 bases:

>100_bases
GCGCGTTGCCACTGCCCGGCCGCGGGGACGGACGCACAAGCCCGGCGAAATCCATGGCACCATGCACGGCTTGATCCGTT
CGATCAGATTTGGAGCCACG

Downstream 100 bases:

>100_bases
AGCCGCCACCGCACCGTCGGCCGAATTCGGAGGCACCGGCTTTGCTAGGTCCATCGAGGCGGCGCCGCTGCAAGCTGTCA
TCGCCTCCCCCGGTCTCGCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MDYRVLLAAFSREAGGEGAGPGRLSQQHRLYASLREAILRRALDADTALPSSRALAETLRIARNSVLYAYERLAAEGFVV
ADRQGTRVARMVLPAEPDADAPLAPPPLSRRATSLGHFSDRAGETGAFVPGVPALDAFPLAAWRRAVERAWRRVGPAQLD
YQPSAGNLPLRHAIVDYLRVSRGVACDADQVLITDGTQHGLDLCARALADAGDVAWIENPGYGGARVALRAAGLRLVPVP
VDAHGLAPAPDLWRSAPPRLVYVTPSHQYPLGAVMSPERRVALVRAARDAGAWIVEDDYDSEFRHHGTPLAALQSSVRDA
PVIYLGTFSKVMFPALRIGFVVVPAAIATELERVSAALAPRGRLADQLALAEFIEAGQFTRHLRRMRRLYAERRDALHDT
LSRRLGGMLTVSAGDGGMHLSARLDAGVSDLDVYRAGRAHGLVIRPLSPFCAPGTDPSAYNGLVLGYGSVAVESMDDAVI
RLERAIGDAHRARRAS

Sequences:

>Translated_496_residues
MDYRVLLAAFSREAGGEGAGPGRLSQQHRLYASLREAILRRALDADTALPSSRALAETLRIARNSVLYAYERLAAEGFVV
ADRQGTRVARMVLPAEPDADAPLAPPPLSRRATSLGHFSDRAGETGAFVPGVPALDAFPLAAWRRAVERAWRRVGPAQLD
YQPSAGNLPLRHAIVDYLRVSRGVACDADQVLITDGTQHGLDLCARALADAGDVAWIENPGYGGARVALRAAGLRLVPVP
VDAHGLAPAPDLWRSAPPRLVYVTPSHQYPLGAVMSPERRVALVRAARDAGAWIVEDDYDSEFRHHGTPLAALQSSVRDA
PVIYLGTFSKVMFPALRIGFVVVPAAIATELERVSAALAPRGRLADQLALAEFIEAGQFTRHLRRMRRLYAERRDALHDT
LSRRLGGMLTVSAGDGGMHLSARLDAGVSDLDVYRAGRAHGLVIRPLSPFCAPGTDPSAYNGLVLGYGSVAVESMDDAVI
RLERAIGDAHRARRAS
>Mature_496_residues
MDYRVLLAAFSREAGGEGAGPGRLSQQHRLYASLREAILRRALDADTALPSSRALAETLRIARNSVLYAYERLAAEGFVV
ADRQGTRVARMVLPAEPDADAPLAPPPLSRRATSLGHFSDRAGETGAFVPGVPALDAFPLAAWRRAVERAWRRVGPAQLD
YQPSAGNLPLRHAIVDYLRVSRGVACDADQVLITDGTQHGLDLCARALADAGDVAWIENPGYGGARVALRAAGLRLVPVP
VDAHGLAPAPDLWRSAPPRLVYVTPSHQYPLGAVMSPERRVALVRAARDAGAWIVEDDYDSEFRHHGTPLAALQSSVRDA
PVIYLGTFSKVMFPALRIGFVVVPAAIATELERVSAALAPRGRLADQLALAEFIEAGQFTRHLRRMRRLYAERRDALHDT
LSRRLGGMLTVSAGDGGMHLSARLDAGVSDLDVYRAGRAHGLVIRPLSPFCAPGTDPSAYNGLVLGYGSVAVESMDDAVI
RLERAIGDAHRARRAS

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=375, Percent_Identity=24.5333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33469970, Length=375, Percent_Identity=24.5333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790797, Length=401, Percent_Identity=27.1820448877805, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787710, Length=437, Percent_Identity=25.858123569794, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321236, Length=311, Percent_Identity=25.08038585209, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53351; Mature: 53351

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRVLLAAFSREAGGEGAGPGRLSQQHRLYASLREAILRRALDADTALPSSRALAETLR
CCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IARNSVLYAYERLAAEGFVVADRQGTRVARMVLPAEPDADAPLAPPPLSRRATSLGHFSD
HHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCHH
RAGETGAFVPGVPALDAFPLAAWRRAVERAWRRVGPAQLDYQPSAGNLPLRHAIVDYLRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRGVACDADQVLITDGTQHGLDLCARALADAGDVAWIENPGYGGARVALRAAGLRLVPVP
HCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCEEEEEEC
VDAHGLAPAPDLWRSAPPRLVYVTPSHQYPLGAVMSPERRVALVRAARDAGAWIVEDDYD
CCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCC
SEFRHHGTPLAALQSSVRDAPVIYLGTFSKVMFPALRIGFVVVPAAIATELERVSAALAP
CHHHHCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGRLADQLALAEFIEAGQFTRHLRRMRRLYAERRDALHDTLSRRLGGMLTVSAGDGGMHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEE
SARLDAGVSDLDVYRAGRAHGLVIRPLSPFCAPGTDPSAYNGLVLGYGSVAVESMDDAVI
EEECCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHH
RLERAIGDAHRARRAS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYRVLLAAFSREAGGEGAGPGRLSQQHRLYASLREAILRRALDADTALPSSRALAETLR
CCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IARNSVLYAYERLAAEGFVVADRQGTRVARMVLPAEPDADAPLAPPPLSRRATSLGHFSD
HHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCHH
RAGETGAFVPGVPALDAFPLAAWRRAVERAWRRVGPAQLDYQPSAGNLPLRHAIVDYLRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRGVACDADQVLITDGTQHGLDLCARALADAGDVAWIENPGYGGARVALRAAGLRLVPVP
HCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCEEEEEEC
VDAHGLAPAPDLWRSAPPRLVYVTPSHQYPLGAVMSPERRVALVRAARDAGAWIVEDDYD
CCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCC
SEFRHHGTPLAALQSSVRDAPVIYLGTFSKVMFPALRIGFVVVPAAIATELERVSAALAP
CHHHHCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGRLADQLALAEFIEAGQFTRHLRRMRRLYAERRDALHDTLSRRLGGMLTVSAGDGGMHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEE
SARLDAGVSDLDVYRAGRAHGLVIRPLSPFCAPGTDPSAYNGLVLGYGSVAVESMDDAVI
EEECCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHH
RLERAIGDAHRARRAS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]