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The map label for this gene is btr [H]

Identifier: 238025067

GI number: 238025067

Start: 2161495

End: 2162259

Strand: Direct

Name: btr [H]

Synonym: bglu_2g17230

Alternate gene names: 238025067

Gene position: 2161495-2162259 (Clockwise)

Preceding gene: 238025066

Following gene: 238025070

Centisome position: 76.45

GC content: 68.5

Gene sequence:

>765_bases
ATGCTGACCGCCACGAAGCCCGCCACCATCGCCTCCGACGTGCCGCCGCCCGCGGCCACGCAGTTCGACGCGCTGAAGCA
GCCCGGCGCGCGCTGTTCGAATTGCGCGACGCGCAACGTCTGCATGCCGTCGGGGCTCACGCACGCCGAATTCCGCCGGC
TCGACACGCTGATCTGCATGACCCGCCACGTCAAGCGCGGCGACGCGCTGTTTCGCGCCCACGACCCGTTCACCAATCTC
TACGCGGTGCGCACCGGCTCGTTCAAGACGCTCGTGATCCACCGGGACGGCCACGAGCAGGTGACCGGCTTCCACATCAC
GGGCGAGACGCTCGGGCTCGACGGCCTCGGCGACGGCGAGCATCACAGCGAGGCGATCGCGCTCGAGGACAGCACCGTCT
GCGTCATCCCGTTCGCGCAGCTCGAGGCGGCGTGCCGCGAGATGCGGCTGCTGCAGCAGCACGTGCATCAGCTGCTGAGC
GGCGAGATCGTGCGCGAATCGCGCGCCATGATGCTGCTCGGCACCATGACGGCCGAGCAACGCGTGGCCTCGTTCCTGCT
GAACCTCTCGGCGCGCTTCAAGGCGCGCGGCTATTCGCCGGCCGAATTCAACCTGCGGATGACGCGCGAGGAAATCGGCT
GCTACCTCGGCATGACGCTCGAAACCGTGAGCCGCATGCTGTCGAAGTTCCAGCGCAGCGGCATGATCGACTCGCGCGGC
CGGCAGATCCGCATCACCGACGCGCAGCGGCTCGTGCAGGTCTGA

Upstream 100 bases:

>100_bases
ACTTCTTCGACAAGACCACGGAATTCGAGCTGGCATGCCACACGATCGACGCGCTCGCCCACGCGCGCCGCCCTCAACCT
GCCCCCGAACGAGTCCCCTC

Downstream 100 bases:

>100_bases
CGCGTGCCGGCGCGCCGCGCCGCACGCTCAGAGACGGAACGCCCCCGGCAGCAGCGCCGCCGCGGTCGTTTCCTGCCGCG
CGCCGCGCAGGTTGGCCAGC

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLTATKPATIASDVPPPAATQFDALKQPGARCSNCATRNVCMPSGLTHAEFRRLDTLICMTRHVKRGDALFRAHDPFTNL
YAVRTGSFKTLVIHRDGHEQVTGFHITGETLGLDGLGDGEHHSEAIALEDSTVCVIPFAQLEAACREMRLLQQHVHQLLS
GEIVRESRAMMLLGTMTAEQRVASFLLNLSARFKARGYSPAEFNLRMTREEIGCYLGMTLETVSRMLSKFQRSGMIDSRG
RQIRITDAQRLVQV

Sequences:

>Translated_254_residues
MLTATKPATIASDVPPPAATQFDALKQPGARCSNCATRNVCMPSGLTHAEFRRLDTLICMTRHVKRGDALFRAHDPFTNL
YAVRTGSFKTLVIHRDGHEQVTGFHITGETLGLDGLGDGEHHSEAIALEDSTVCVIPFAQLEAACREMRLLQQHVHQLLS
GEIVRESRAMMLLGTMTAEQRVASFLLNLSARFKARGYSPAEFNLRMTREEIGCYLGMTLETVSRMLSKFQRSGMIDSRG
RQIRITDAQRLVQV
>Mature_254_residues
MLTATKPATIASDVPPPAATQFDALKQPGARCSNCATRNVCMPSGLTHAEFRRLDTLICMTRHVKRGDALFRAHDPFTNL
YAVRTGSFKTLVIHRDGHEQVTGFHITGETLGLDGLGDGEHHSEAIALEDSTVCVIPFAQLEAACREMRLLQQHVHQLLS
GEIVRESRAMMLLGTMTAEQRVASFLLNLSARFKARGYSPAEFNLRMTREEIGCYLGMTLETVSRMLSKFQRSGMIDSRG
RQIRITDAQRLVQV

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=43.4977578475336, Blast_Score=203, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28216; Mature: 28216

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTATKPATIASDVPPPAATQFDALKQPGARCSNCATRNVCMPSGLTHAEFRRLDTLICM
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
TRHVKRGDALFRAHDPFTNLYAVRTGSFKTLVIHRDGHEQVTGFHITGETLGLDGLGDGE
HHHHHCCCCEEEECCCCCCEEEEECCCEEEEEEEECCCCCEEEEEEECCEECCCCCCCCC
HHSEAIALEDSTVCVIPFAQLEAACREMRLLQQHVHQLLSGEIVRESRAMMLLGTMTAEQ
CCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHH
RVASFLLNLSARFKARGYSPAEFNLRMTREEIGCYLGMTLETVSRMLSKFQRSGMIDSRG
HHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHCCHHCCHHHHHHHHHHHHHHCCCCCCCC
RQIRITDAQRLVQV
CEEEEECHHHHHCC
>Mature Secondary Structure
MLTATKPATIASDVPPPAATQFDALKQPGARCSNCATRNVCMPSGLTHAEFRRLDTLICM
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
TRHVKRGDALFRAHDPFTNLYAVRTGSFKTLVIHRDGHEQVTGFHITGETLGLDGLGDGE
HHHHHCCCCEEEECCCCCCEEEEECCCEEEEEEEECCCCCEEEEEEECCEECCCCCCCCC
HHSEAIALEDSTVCVIPFAQLEAACREMRLLQQHVHQLLSGEIVRESRAMMLLGTMTAEQ
CCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHH
RVASFLLNLSARFKARGYSPAEFNLRMTREEIGCYLGMTLETVSRMLSKFQRSGMIDSRG
HHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHCCHHCCHHHHHHHHHHHHHHCCCCCCCC
RQIRITDAQRLVQV
CEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]