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The map label for this gene is soxB [H]

Identifier: 238024780

GI number: 238024780

Start: 1812280

End: 1813608

Strand: Reverse

Name: soxB [H]

Synonym: bglu_2g14180

Alternate gene names: 238024780

Gene position: 1813608-1812280 (Counterclockwise)

Preceding gene: 238024783

Following gene: 238024779

Centisome position: 64.15

GC content: 74.49

Gene sequence:

>1329_bases
ATGACCACCACCTATCCGCTGTACCGCGCGTTTTCCCGCGCGGACGAACCGTTTCCGACGCAAGCCGAGGTCGTGATCGC
CGGCGCCGGCATCATGGGCTGCGCGGCGGCCTACTATCTCGCCCGGCGCGGCATCCGGGCGGTGGTGTTCGACAAGTCGC
GCGTGGCGGGCCAGCAGTCCACGCGCGCCTGGGGCTTCGTGCGCCAGCAGGGGCGCGAGGCCGCCGAGGTGCCGCTGATG
ATGGCCGGCATGCGGATCTGGGAGGGGCTCGAGGCCGAACTCGGCGCCGATCTCGAATGGCGCCAGGGCGGCTGCCTCTA
TCTGGCCGACCAGGACGAGGACTGGGCCGCGTTCCAGGACTGGCTCGGCGTGGCGCGCGAGCATGGGCTCGATACCCGTG
CACTCGCGCCCGCCGAGGTCGGGCGCCATGTGACGGGGCTCGCCGCGCCGGTACTCGGCGGCCTGTACACCGCCTCCGAC
GGGCAGGCCGAGCCGCGCCGCGTGGCGCCCGCGTTCGCCGCGCGCGCCATCGAGCGCGGCGCGCGCTTCTTCGACGGCTG
CGGCGTGAGCGCGATCGAGACGGCGGGCGGCGCGGTGACGGGCGTGGTGACCGAGCGCGGCCTCGTGAAGACCTCGCGCG
TGATCTGCGCGGCCGGCGCGGCCAGCTTCCGGCTGCTCGACGGGGTGGGCATCCGCCTGCCGCAGCAGACCGTGCGCGGC
ACCTGCATCCGCACCAACGCGCTGCCGGCCGTGTCGGCGGCGACCCTCTGGGGCCACGGGCTCGGCATACGCCAGCGCGC
CGACGGCGCCATCAACCTGGCCGACGACATGAGCGTCGACGTCGACCTGACGCTCGGCCATCTGCGCGGGCTGTCGCTGT
TCATGCCTGAACTCTGGAAGCATCGCCGGAAATTCCGGCTTCATCTGAACGGCGCGCTGCTCGGCGACCTCGCGCGGCGC
ATCGGCGGCGGCCCCGGCGCGATCGAGCCGCGCGAGCCGCAGCCGCGCCCCAATCCCGCGCAGGGGCCGCGCGCGCTGGC
GCGGCTCAGGCGGATCTTCCCGGCGCTCGCGGCGGCGCAGGCCGTCGAGAGCTGGGCCGGGCTGATCGACGTGCTGCCCG
ACGGGATTCCGGTGATCGACGCGCCCGACGCGGTGCGCGGGCTCGCCATCGCGACCGGCTTCTGCGGGCACGGCTTCGCG
ATGGGGCCGATCGTCGGGCGGCTGCTCGCGGAGCTGATCGATGGCGGCGCGCCGTCGCTCGAACTGGGCGCGTTTCGGGC
GCGCCGCTTCGTCGACGGCACCATGCAGCGGCCGCGCAGCATGCTGTGA

Upstream 100 bases:

>100_bases
GCCGCCGGCCGCTCGCGGCCGGCCGGTAGAATGGCACGACCGCCGAGGCGGCATCCCGCCGCCCCGCCATCATCGCCTTG
CCGACCGCCCGACGCCCCGC

Downstream 100 bases:

>100_bases
AGGACGACGGGCGGGCGGCCGGGGCCGGGCGCCCGCGACCGTCCGATGCGCCGCCGCGGGCGGGCGTGCCGGGCACGCGC
TGCCCGAGACGCGTCGGCGG

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTTTYPLYRAFSRADEPFPTQAEVVIAGAGIMGCAAAYYLARRGIRAVVFDKSRVAGQQSTRAWGFVRQQGREAAEVPLM
MAGMRIWEGLEAELGADLEWRQGGCLYLADQDEDWAAFQDWLGVAREHGLDTRALAPAEVGRHVTGLAAPVLGGLYTASD
GQAEPRRVAPAFAARAIERGARFFDGCGVSAIETAGGAVTGVVTERGLVKTSRVICAAGAASFRLLDGVGIRLPQQTVRG
TCIRTNALPAVSAATLWGHGLGIRQRADGAINLADDMSVDVDLTLGHLRGLSLFMPELWKHRRKFRLHLNGALLGDLARR
IGGGPGAIEPREPQPRPNPAQGPRALARLRRIFPALAAAQAVESWAGLIDVLPDGIPVIDAPDAVRGLAIATGFCGHGFA
MGPIVGRLLAELIDGGAPSLELGAFRARRFVDGTMQRPRSML

Sequences:

>Translated_442_residues
MTTTYPLYRAFSRADEPFPTQAEVVIAGAGIMGCAAAYYLARRGIRAVVFDKSRVAGQQSTRAWGFVRQQGREAAEVPLM
MAGMRIWEGLEAELGADLEWRQGGCLYLADQDEDWAAFQDWLGVAREHGLDTRALAPAEVGRHVTGLAAPVLGGLYTASD
GQAEPRRVAPAFAARAIERGARFFDGCGVSAIETAGGAVTGVVTERGLVKTSRVICAAGAASFRLLDGVGIRLPQQTVRG
TCIRTNALPAVSAATLWGHGLGIRQRADGAINLADDMSVDVDLTLGHLRGLSLFMPELWKHRRKFRLHLNGALLGDLARR
IGGGPGAIEPREPQPRPNPAQGPRALARLRRIFPALAAAQAVESWAGLIDVLPDGIPVIDAPDAVRGLAIATGFCGHGFA
MGPIVGRLLAELIDGGAPSLELGAFRARRFVDGTMQRPRSML
>Mature_441_residues
TTTYPLYRAFSRADEPFPTQAEVVIAGAGIMGCAAAYYLARRGIRAVVFDKSRVAGQQSTRAWGFVRQQGREAAEVPLMM
AGMRIWEGLEAELGADLEWRQGGCLYLADQDEDWAAFQDWLGVAREHGLDTRALAPAEVGRHVTGLAAPVLGGLYTASDG
QAEPRRVAPAFAARAIERGARFFDGCGVSAIETAGGAVTGVVTERGLVKTSRVICAAGAASFRLLDGVGIRLPQQTVRGT
CIRTNALPAVSAATLWGHGLGIRQRADGAINLADDMSVDVDLTLGHLRGLSLFMPELWKHRRKFRLHLNGALLGDLARRI
GGGPGAIEPREPQPRPNPAQGPRALARLRRIFPALAAAQAVESWAGLIDVLPDGIPVIDAPDAVRGLAIATGFCGHGFAM
GPIVGRLLAELIDGGAPSLELGAFRARRFVDGTMQRPRSML

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=438, Percent_Identity=23.5159817351598, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI21361378, Length=438, Percent_Identity=23.5159817351598, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24797151, Length=431, Percent_Identity=22.969837587007, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI194306651, Length=210, Percent_Identity=24.2857142857143, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130091, Length=431, Percent_Identity=22.737819025522, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571104, Length=243, Percent_Identity=26.7489711934156, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 47049; Mature: 46917

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTYPLYRAFSRADEPFPTQAEVVIAGAGIMGCAAAYYLARRGIRAVVFDKSRVAGQQS
CCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHCCCCH
TRAWGFVRQQGREAAEVPLMMAGMRIWEGLEAELGADLEWRQGGCLYLADQDEDWAAFQD
HHHHHHHHHHCCCHHHCHHHHHHHHHHCCCHHHHCCCCEECCCCEEEEECCCCCHHHHHH
WLGVAREHGLDTRALAPAEVGRHVTGLAAPVLGGLYTASDGQAEPRRVAPAFAARAIERG
HHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHC
ARFFDGCGVSAIETAGGAVTGVVTERGLVKTSRVICAAGAASFRLLDGVGIRLPQQTVRG
CHHHCCCCCHHHHHCCCCEEEEHHCCCHHHHHHHHEECCCCHHHHCCCCCCCCCHHHHCC
TCIRTNALPAVSAATLWGHGLGIRQRADGAINLADDMSVDVDLTLGHLRGLSLFMPELWK
EEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEEEHHHHCCHHHHHHHHHH
HRRKFRLHLNGALLGDLARRIGGGPGAIEPREPQPRPNPAQGPRALARLRRIFPALAAAQ
HHHHEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVESWAGLIDVLPDGIPVIDAPDAVRGLAIATGFCGHGFAMGPIVGRLLAELIDGGAPSL
HHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
ELGAFRARRFVDGTMQRPRSML
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTTYPLYRAFSRADEPFPTQAEVVIAGAGIMGCAAAYYLARRGIRAVVFDKSRVAGQQS
CCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHCCCCH
TRAWGFVRQQGREAAEVPLMMAGMRIWEGLEAELGADLEWRQGGCLYLADQDEDWAAFQD
HHHHHHHHHHCCCHHHCHHHHHHHHHHCCCHHHHCCCCEECCCCEEEEECCCCCHHHHHH
WLGVAREHGLDTRALAPAEVGRHVTGLAAPVLGGLYTASDGQAEPRRVAPAFAARAIERG
HHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHC
ARFFDGCGVSAIETAGGAVTGVVTERGLVKTSRVICAAGAASFRLLDGVGIRLPQQTVRG
CHHHCCCCCHHHHHCCCCEEEEHHCCCHHHHHHHHEECCCCHHHHCCCCCCCCCHHHHCC
TCIRTNALPAVSAATLWGHGLGIRQRADGAINLADDMSVDVDLTLGHLRGLSLFMPELWK
EEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEEEHHHHCCHHHHHHHHHH
HRRKFRLHLNGALLGDLARRIGGGPGAIEPREPQPRPNPAQGPRALARLRRIFPALAAAQ
HHHHEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVESWAGLIDVLPDGIPVIDAPDAVRGLAIATGFCGHGFAMGPIVGRLLAELIDGGAPSL
HHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
ELGAFRARRFVDGTMQRPRSML
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]