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The map label for this gene is tcp [H]

Identifier: 238024783

GI number: 238024783

Start: 1816891

End: 1818444

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g14210

Alternate gene names: 238024783

Gene position: 1818444-1816891 (Counterclockwise)

Preceding gene: 238024786

Following gene: 238024780

Centisome position: 64.32

GC content: 70.59

Gene sequence:

>1554_bases
ATGAACGCCCTGTTTTCCCGCTTTTCGATCCGTACCCGCCTCTATTCGACGCTGGCCCTGGCCGCCGCGCTGCTCTGCGT
GACCGGCCTGATCGGTCTGTTCGGCATGCAGGGCTCGAACGACGCGCTGAAGAACGCCTATCTCTACGAACTCGCCGGCA
AGACGGCCCTGGGCTCGGCGAACCTGAACCTGACGATCGCGCGCACCACCATCGACCGCGCCATCCTGCATCCGGACAAC
CCGGACCTGCAGTCGGTGCTCGACAAGGCCGAATCGTATCTGGCGACTTCCGACAAGGCCTGGAACGACTACATCTCGCT
GCCGCACCAGGACGGCGAGCAGCCGCTTGCGGACGCGGTCGGCAGCGCGCGCGGCGCATTCATCTCGCAGGCGATCCGGC
CGATGCTGGACGCGGTACGCGGCGGCCGTGCCGACGAGGCCGACCGCCTGGTGATGAAGGTCGCGCCGCCGCTGGCGGTG
GCGCTTTCCAAGGCCACCGCCGATCTCGACGCGTTCGACATGCAGCGCGGGCGCCAGGAGTACGAGGGCGCGCAGCAGCG
CTTCTCGACGCTGCGCCTGATTGCGCTGGCAACCATCGTGATCGGGCTCGGCGCCTGCCTGGGCTGCGCGATCGGGCTCC
ACTACGCGATCACGCGCCCGCTCGCGCACCTGCTCGATCATTTCCGCCGGCTCTCCGACGGCGATCTGACGCGCGAGCTG
CAATGGAGCTCGCGCGACGAGATGGCCGAACTCGTGAGCGGCGTCACGCGCATGCAGCGCAACCTGGCGGAGACGGTCCG
GCGCGTGATGCACGGCTCGGAGTCGATCGCCACCGCCACGCGCCAGATCTCGGCCGGCAACACCGATCTCTCGCAGCGCA
CCGAGGAGCAGGCCGCCACGCTCGAACAGACCGCGGCCAGCATGGCGCAGCTGACCACCACCGTGCGCCAGAACGCCGAC
CATGCGCGCGACGCCCGCGAATCGGCCGACGACGCCACCCGCATCGCCTCGCAGGGCGCCTCGGTGGTGAGCGAGGTGGT
CGGCACCATGAACGACATCGATCGCAGCTCGCAGCGCGTGGCCGACATCATCGGCACGATCGAGGGCATCGCGTTCCAGA
CCAACATCCTGGCGCTGAACGCGGCGGTGGAGGCGGCGCGGGCCGGCGAGCAGGGCCGCGGCTTCGCGGTGGTGGCGGGC
GAGGTGCGCACGCTCGCGCAGCGTTCGGCCAGCGCCGCCAAGGAGATCCGCGCGCTGATCGGCGAATCGGTGGAGCGCGT
CGCGGCCGGCTCGCGGCTGGTCGGCACGGCCGGCAACACCATGAACGAGATCCGCGACGCCATCACGCGCGTCAACGACA
GCATGGCCGCGATCGCGGCCGCCTCCGACGAGCAGCGCGACGGCATCGAGCAGGTCAGCCGCGCGGTCTCGCAGATGGAC
GAGGTCTCGCAGCAGAACGCGGCGCTCGTCGAGCAGGCTGCGGCCGCGGCCTCCGCGCTCGAGGAGCAGGCCAACGGACT
GCGCGAGGCGGTGCGCGCGTTCCGCGTGGCCTGA

Upstream 100 bases:

>100_bases
CCCCGATCGCGGCGACTCAAGTTTTTCAGCCCCGGACCGTAAATGTCGTCAGCAAATGATTTGCGCGCAAGTGCCATTCA
ATCCTGTCGACCGGTCTGCC

Downstream 100 bases:

>100_bases
GCCGGCGCGCCGCGGCCGGGGCGACGCAAGGGGCGCGATCCGCCGCGTCCCGCGTCCCGCGTCGCCGGCGTGACCGGCGC
GCCGGAAGGGATGCCCGGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MNALFSRFSIRTRLYSTLALAAALLCVTGLIGLFGMQGSNDALKNAYLYELAGKTALGSANLNLTIARTTIDRAILHPDN
PDLQSVLDKAESYLATSDKAWNDYISLPHQDGEQPLADAVGSARGAFISQAIRPMLDAVRGGRADEADRLVMKVAPPLAV
ALSKATADLDAFDMQRGRQEYEGAQQRFSTLRLIALATIVIGLGACLGCAIGLHYAITRPLAHLLDHFRRLSDGDLTREL
QWSSRDEMAELVSGVTRMQRNLAETVRRVMHGSESIATATRQISAGNTDLSQRTEEQAATLEQTAASMAQLTTTVRQNAD
HARDARESADDATRIASQGASVVSEVVGTMNDIDRSSQRVADIIGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSASAAKEIRALIGESVERVAAGSRLVGTAGNTMNEIRDAITRVNDSMAAIAAASDEQRDGIEQVSRAVSQMD
EVSQQNAALVEQAAAAASALEEQANGLREAVRAFRVA

Sequences:

>Translated_517_residues
MNALFSRFSIRTRLYSTLALAAALLCVTGLIGLFGMQGSNDALKNAYLYELAGKTALGSANLNLTIARTTIDRAILHPDN
PDLQSVLDKAESYLATSDKAWNDYISLPHQDGEQPLADAVGSARGAFISQAIRPMLDAVRGGRADEADRLVMKVAPPLAV
ALSKATADLDAFDMQRGRQEYEGAQQRFSTLRLIALATIVIGLGACLGCAIGLHYAITRPLAHLLDHFRRLSDGDLTREL
QWSSRDEMAELVSGVTRMQRNLAETVRRVMHGSESIATATRQISAGNTDLSQRTEEQAATLEQTAASMAQLTTTVRQNAD
HARDARESADDATRIASQGASVVSEVVGTMNDIDRSSQRVADIIGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSASAAKEIRALIGESVERVAAGSRLVGTAGNTMNEIRDAITRVNDSMAAIAAASDEQRDGIEQVSRAVSQMD
EVSQQNAALVEQAAAAASALEEQANGLREAVRAFRVA
>Mature_517_residues
MNALFSRFSIRTRLYSTLALAAALLCVTGLIGLFGMQGSNDALKNAYLYELAGKTALGSANLNLTIARTTIDRAILHPDN
PDLQSVLDKAESYLATSDKAWNDYISLPHQDGEQPLADAVGSARGAFISQAIRPMLDAVRGGRADEADRLVMKVAPPLAV
ALSKATADLDAFDMQRGRQEYEGAQQRFSTLRLIALATIVIGLGACLGCAIGLHYAITRPLAHLLDHFRRLSDGDLTREL
QWSSRDEMAELVSGVTRMQRNLAETVRRVMHGSESIATATRQISAGNTDLSQRTEEQAATLEQTAASMAQLTTTVRQNAD
HARDARESADDATRIASQGASVVSEVVGTMNDIDRSSQRVADIIGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSASAAKEIRALIGESVERVAAGSRLVGTAGNTMNEIRDAITRVNDSMAAIAAASDEQRDGIEQVSRAVSQMD
EVSQQNAALVEQAAAAASALEEQANGLREAVRAFRVA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=60.1307189542484, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1787690, Length=429, Percent_Identity=46.1538461538462, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI2367378, Length=526, Percent_Identity=41.8250950570342, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1788194, Length=334, Percent_Identity=51.7964071856287, Blast_Score=295, Evalue=6e-81,
Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=36.9230769230769, Blast_Score=188, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55075; Mature: 55075

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALFSRFSIRTRLYSTLALAAALLCVTGLIGLFGMQGSNDALKNAYLYELAGKTALGSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCC
NLNLTIARTTIDRAILHPDNPDLQSVLDKAESYLATSDKAWNDYISLPHQDGEQPLADAV
CCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHH
GSARGAFISQAIRPMLDAVRGGRADEADRLVMKVAPPLAVALSKATADLDAFDMQRGRQE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YEGAQQRFSTLRLIALATIVIGLGACLGCAIGLHYAITRPLAHLLDHFRRLSDGDLTREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QWSSRDEMAELVSGVTRMQRNLAETVRRVMHGSESIATATRQISAGNTDLSQRTEEQAAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LEQTAASMAQLTTTVRQNADHARDARESADDATRIASQGASVVSEVVGTMNDIDRSSQRV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADIIGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSASAAKEIRALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
GESVERVAAGSRLVGTAGNTMNEIRDAITRVNDSMAAIAAASDEQRDGIEQVSRAVSQMD
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVSQQNAALVEQAAAAASALEEQANGLREAVRAFRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNALFSRFSIRTRLYSTLALAAALLCVTGLIGLFGMQGSNDALKNAYLYELAGKTALGSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCC
NLNLTIARTTIDRAILHPDNPDLQSVLDKAESYLATSDKAWNDYISLPHQDGEQPLADAV
CCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHH
GSARGAFISQAIRPMLDAVRGGRADEADRLVMKVAPPLAVALSKATADLDAFDMQRGRQE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YEGAQQRFSTLRLIALATIVIGLGACLGCAIGLHYAITRPLAHLLDHFRRLSDGDLTREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QWSSRDEMAELVSGVTRMQRNLAETVRRVMHGSESIATATRQISAGNTDLSQRTEEQAAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LEQTAASMAQLTTTVRQNADHARDARESADDATRIASQGASVVSEVVGTMNDIDRSSQRV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADIIGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSASAAKEIRALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
GESVERVAAGSRLVGTAGNTMNEIRDAITRVNDSMAAIAAASDEQRDGIEQVSRAVSQMD
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVSQQNAALVEQAAAAASALEEQANGLREAVRAFRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]