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The map label for this gene is shiA [H]

Identifier: 238024555

GI number: 238024555

Start: 1474973

End: 1476277

Strand: Direct

Name: shiA [H]

Synonym: bglu_2g11620

Alternate gene names: 238024555

Gene position: 1474973-1476277 (Clockwise)

Preceding gene: 238024552

Following gene: 238024556

Centisome position: 52.17

GC content: 69.96

Gene sequence:

>1305_bases
ATGACCCCCGCTTACGATTCACTCGATCAGGCCGGCGCGCAACGCGCGCGCAGCCAGGCCCGCAAGGCGGCGCTCGGCAG
TTTCGTCGGCGCCGTGGTCGACTGGTACGACTTCCTGCTGTACGGGATCGTCGCCGCGCTGGTATTCAACGCCGCGTTCT
TCCCGAAGGTCAGCCCCACCATGGGCACGCTCGCCGCGTTCGCCACGTTCGGCGTCGGCTTCCTGTTCCGCCCGCTCGGC
GGCGTGGTGTTCGGCCACTACGGCGACCGGCTCGGCCGCAAGCGCATGCTGGTGCTGACGGTGATGATGATGGGCGTGTC
GACGGTGGCGATCGGCCTGCTGCCGAGCTTCGCCAGCATCGGCTGGTGGGCGCCGGTGCTGCTGGTGCTGCTGCGCGCGC
TGCAGGGCTTCGCGGTGGGCGGCGAATGGGGCGGCGCGGCGCTGATGGCGGTGGAAAGCGCCCCGGCCAAGCGCAAGGCG
TTCTACAGCAGCGGCGTGCAGGTGGGCTACGGCGTGGGCCTCGTGCTGGCCACCGGCATCGTCTCGCTGCTGAGCAGCAC
GCTCGGCGACGACGCGTTTCGCGCCTGGGCCTGGCGCATCCCGTTCCTCGCCAGCGCGGTGCTGGTGCTGATCGGCCTGT
GGGTGCGTTCGAGCATGGACGAATCGCAGGAGTTCGTGGAAAAGGTCGAGCACGCCCGCCGCAAGCTGCGGATGCCGGTG
CTCGAGGCGCTCTCGCGCCATCCGCGCGCGTTCCTCTACATCGTCGCGCTGCGGCTCGCCGAGCTGTTCTCGATGTACAT
CGTCACCGCGTTCGCGCTCAGCTACTCCACCGCCAATCTCGGCATGCCGCGCGAGCTGTTCCTGAACATCGGCCTGCTGG
TGGGCGCGATCAGCTGCGTGACGATCCCCTGCTTCGCCTGGCTCGCCGACCGCTTCGGCCTGCGCCGCGTCTACATCACC
GGCGCGCTGATCGGGCTCGCCTCGGCGGTGCCGTTCTTCGTCGCGCTGGAAGCGCGCTCCACGGTCTGGATCGTGATCTT
CGCGGTGATGCTGGCCAACGTCGCGCACGACATGGTGGTGAGCGTGCAGCAGCCGCTCTTCACCGAGCTGTTCGGCGCCG
AGTATCGCTACAGCGGCGCGGGCGTCGGCTACCAGTTCGCGAGCGTGGTCGGCGGCGGCTTCACGCCGTTCATCGCGGTG
GCGCTGGTCAGCGTCGGCGGCGGCTCGTGGCACCTGGTGGCCGCCTATCTCGCGCTCGGCTGCCTGATCTCGGTGCTGGT
CGCCGCGCGCATGCGCGCGGCCTGA

Upstream 100 bases:

>100_bases
CCCTATGCTGCGTGCAATTTCCGTCGCGACGACAGCCAGGCGCGGCGGCACGCATCGGCCGGCGGCGCCTCGTGCCGGCC
CGGGATACCAGGAGACACCC

Downstream 100 bases:

>100_bases
GCGCGGCCGGCAGCGAACGACGGCGGCCGGCCGCTGGTTCCGATGAAAAAAGCCCCTCTCGACAAGCGCGACTGGATCGC
CGGCCTGGAAAAAGGCCTGA

Product: shikimate transporter

Products: Proton [Cytoplasm]; shikimate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTPAYDSLDQAGAQRARSQARKAALGSFVGAVVDWYDFLLYGIVAALVFNAAFFPKVSPTMGTLAAFATFGVGFLFRPLG
GVVFGHYGDRLGRKRMLVLTVMMMGVSTVAIGLLPSFASIGWWAPVLLVLLRALQGFAVGGEWGGAALMAVESAPAKRKA
FYSSGVQVGYGVGLVLATGIVSLLSSTLGDDAFRAWAWRIPFLASAVLVLIGLWVRSSMDESQEFVEKVEHARRKLRMPV
LEALSRHPRAFLYIVALRLAELFSMYIVTAFALSYSTANLGMPRELFLNIGLLVGAISCVTIPCFAWLADRFGLRRVYIT
GALIGLASAVPFFVALEARSTVWIVIFAVMLANVAHDMVVSVQQPLFTELFGAEYRYSGAGVGYQFASVVGGGFTPFIAV
ALVSVGGGSWHLVAAYLALGCLISVLVAARMRAA

Sequences:

>Translated_434_residues
MTPAYDSLDQAGAQRARSQARKAALGSFVGAVVDWYDFLLYGIVAALVFNAAFFPKVSPTMGTLAAFATFGVGFLFRPLG
GVVFGHYGDRLGRKRMLVLTVMMMGVSTVAIGLLPSFASIGWWAPVLLVLLRALQGFAVGGEWGGAALMAVESAPAKRKA
FYSSGVQVGYGVGLVLATGIVSLLSSTLGDDAFRAWAWRIPFLASAVLVLIGLWVRSSMDESQEFVEKVEHARRKLRMPV
LEALSRHPRAFLYIVALRLAELFSMYIVTAFALSYSTANLGMPRELFLNIGLLVGAISCVTIPCFAWLADRFGLRRVYIT
GALIGLASAVPFFVALEARSTVWIVIFAVMLANVAHDMVVSVQQPLFTELFGAEYRYSGAGVGYQFASVVGGGFTPFIAV
ALVSVGGGSWHLVAAYLALGCLISVLVAARMRAA
>Mature_433_residues
TPAYDSLDQAGAQRARSQARKAALGSFVGAVVDWYDFLLYGIVAALVFNAAFFPKVSPTMGTLAAFATFGVGFLFRPLGG
VVFGHYGDRLGRKRMLVLTVMMMGVSTVAIGLLPSFASIGWWAPVLLVLLRALQGFAVGGEWGGAALMAVESAPAKRKAF
YSSGVQVGYGVGLVLATGIVSLLSSTLGDDAFRAWAWRIPFLASAVLVLIGLWVRSSMDESQEFVEKVEHARRKLRMPVL
EALSRHPRAFLYIVALRLAELFSMYIVTAFALSYSTANLGMPRELFLNIGLLVGAISCVTIPCFAWLADRFGLRRVYITG
ALIGLASAVPFFVALEARSTVWIVIFAVMLANVAHDMVVSVQQPLFTELFGAEYRYSGAGVGYQFASVVGGGFTPFIAVA
LVSVGGGSWHLVAAYLALGCLISVLVAARMRAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788292, Length=417, Percent_Identity=74.1007194244604, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI1789941, Length=433, Percent_Identity=38.3371824480369, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1790550, Length=426, Percent_Identity=32.8638497652582, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1788942, Length=404, Percent_Identity=32.4257425742574, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87082404, Length=388, Percent_Identity=23.4536082474227, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082231, Length=450, Percent_Identity=21.5555555555556, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46457; Mature: 46326

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCC
>Mature Secondary Structure 
TPAYDSLDQAGAQRARSQARKAALGSFVGAVVDWYDFLLYGIVAALVFNAAFFPKVSPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
MGTLAAFATFGVGFLFRPLGGVVFGHYGDRLGRKRMLVLTVMMMGVSTVAIGLLPSFASI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWWAPVLLVLLRALQGFAVGGEWGGAALMAVESAPAKRKAFYSSGVQVGYGVGLVLATGI
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VSLLSSTLGDDAFRAWAWRIPFLASAVLVLIGLWVRSSMDESQEFVEKVEHARRKLRMPV
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
LEALSRHPRAFLYIVALRLAELFSMYIVTAFALSYSTANLGMPRELFLNIGLLVGAISCV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TIPCFAWLADRFGLRRVYITGALIGLASAVPFFVALEARSTVWIVIFAVMLANVAHDMVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHH
SVQQPLFTELFGAEYRYSGAGVGYQFASVVGGGFTPFIAVALVSVGGGSWHLVAAYLALG
HHHHHHHHHHHCCCCEECCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
CLISVLVAARMRAA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; shikimate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + shikimate [Periplasm] = Proton [Cytoplasm] + shikimate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9524262; 9097040; 9278503 [H]