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The map label for this gene is ribH2 [H]

Identifier: 238024530

GI number: 238024530

Start: 1449302

End: 1449823

Strand: Reverse

Name: ribH2 [H]

Synonym: bglu_2g11360

Alternate gene names: 238024530

Gene position: 1449823-1449302 (Counterclockwise)

Preceding gene: 238024531

Following gene: 238024528

Centisome position: 51.28

GC content: 67.82

Gene sequence:

>522_bases
ATGACTCAGATTTCCCCAGCCTCCCCGGCATTCCCGCGCCGTATCGCGTTCGTCCAGTCGTGCTGGCACAAGGACATCGT
GGATCAGTGCAAGACCGCGTTCATGGCCGCGCTTGCCGAGGCCGGCATCGCCGGCACCGAGATCGACTGCTTCGAGGTGG
CGGGCGCGTTCGAGATTCCGCTGCATGCGAAGCTGCTGGCCAAGACCGGCCGGTACGCCGCGGTGGCCTGCGCGGGGCTG
GTGGTGGACGGCGGCATCTACCGGCACGAGTTCGTCGCGCAGGCGGTGATCTCGGGGCTGATGCAGGTGCAGCTCGAAAC
CGGCACCGTGGTGCTGAGCGCCGTGCTCACGCCGCATCATTTCCATCACGGCTCGCACGAGCACGCCAGATTCTTCCACG
AGCATTTCGTCGTGAAGGGCGCCGAACTCGCGCATGCCTGCGCCGACACGATCGCGAAGGTGGCGAAGCTGCATGCCAGC
GCAGGCGGCGCGACCGGCGCCGGGGTGCTGCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGTCATAGTCCGGATGAGAGAGAGCGGGGTTTTTCCGCACGCGCAAGGCGTGCGGCGCGGCCCTGTGCGCCCATTCAAC
TCGTACACAGGACCTTGTCG

Downstream 100 bases:

>100_bases
GGTTCGAGCGGCGCCGCCCGTGCCGCCCGCATCGCGTTCCGGGCGCGGGCGGCGGGGTGCCCGCGCTCAGCGCTCCGGGC
GGCTCGGTTGCAGCGGCGCC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase 2; Lumazine synthase 2; Riboflavin synthase 2 beta chain [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTQISPASPAFPRRIAFVQSCWHKDIVDQCKTAFMAALAEAGIAGTEIDCFEVAGAFEIPLHAKLLAKTGRYAAVACAGL
VVDGGIYRHEFVAQAVISGLMQVQLETGTVVLSAVLTPHHFHHGSHEHARFFHEHFVVKGAELAHACADTIAKVAKLHAS
AGGATGAGVLQAA

Sequences:

>Translated_173_residues
MTQISPASPAFPRRIAFVQSCWHKDIVDQCKTAFMAALAEAGIAGTEIDCFEVAGAFEIPLHAKLLAKTGRYAAVACAGL
VVDGGIYRHEFVAQAVISGLMQVQLETGTVVLSAVLTPHHFHHGSHEHARFFHEHFVVKGAELAHACADTIAKVAKLHAS
AGGATGAGVLQAA
>Mature_172_residues
TQISPASPAFPRRIAFVQSCWHKDIVDQCKTAFMAALAEAGIAGTEIDCFEVAGAFEIPLHAKLLAKTGRYAAVACAGLV
VDGGIYRHEFVAQAVISGLMQVQLETGTVVLSAVLTPHHFHHGSHEHARFFHEHFVVKGAELAHACADTIAKVAKLHASA
GGATGAGVLQAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 18176; Mature: 18045

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQISPASPAFPRRIAFVQSCWHKDIVDQCKTAFMAALAEAGIAGTEIDCFEVAGAFEIP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCC
LHAKLLAKTGRYAAVACAGLVVDGGIYRHEFVAQAVISGLMQVQLETGTVVLSAVLTPHH
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHH
FHHGSHEHARFFHEHFVVKGAELAHACADTIAKVAKLHASAGGATGAGVLQAA
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQISPASPAFPRRIAFVQSCWHKDIVDQCKTAFMAALAEAGIAGTEIDCFEVAGAFEIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCC
LHAKLLAKTGRYAAVACAGLVVDGGIYRHEFVAQAVISGLMQVQLETGTVVLSAVLTPHH
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHH
FHHGSHEHARFFHEHFVVKGAELAHACADTIAKVAKLHASAGGATGAGVLQAA
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]