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The map label for this gene is bcd [H]

Identifier: 238024524

GI number: 238024524

Start: 1443936

End: 1445114

Strand: Reverse

Name: bcd [H]

Synonym: bglu_2g11300

Alternate gene names: 238024524

Gene position: 1445114-1443936 (Counterclockwise)

Preceding gene: 238024526

Following gene: 238024523

Centisome position: 51.11

GC content: 67.94

Gene sequence:

>1179_bases
ATGAGCAACCTGCCCGGCGTGCAATTCATGCTCGGTGAGGACATCGAGATGCTGCGCGACGCGATCGCCACGTTCGCCGC
GAAGGAGATCGCGCCGCGCGCGGCCGAGATCGATCGCACCGACCAGTTCCCGATGGACCTGTGGCGCAAGTTCGGCGAAC
TCGGCGTGCTCGGCATGACGGTGGGCGAGGAGTACGGCGGCGCGAACCTCGGCTACACGGCGCACATGGTGGCGATGGAG
GAAATCTCGCGCGCCTCGGCATCGGTCGGCCTGTCCTACGGCGCCCATTCGAATCTCTGCGTCAACCAGATCCATCGCAA
CGGCAGCGAGGCGCAGAAGCGCCGCTACCTGCCGAAGCTGATCTCGGGCGAGCACGTGGGGGCGCTGGCGATGAGCGAGC
CGAACGCGGGCTCGGACGTGGTCAGCATGAAGCTGCGCGCCGACCGGCGCGGCAGCCACTACGTGCTGAACGGCACCAAG
ATGTGGATCACCAACGGCCCGGACTGCGACACGCTGGTGGTCTACGCGAAGACCGATCCGGAGGCGGGTGCGCGCGGCAT
GACGGCGTTCATCGTCGAGAAGGGCATGAAGGGCTTCTCGGTGGCGCAGAAGCTCGACAAGCTCGGCATGCGCGGCTCGC
ACACGGGCGAGCTGGTGTTCCAGGACGTGGAGGTGCCCGAGGAGAACGTGCTGGGCGAGGTGGGCAGCGGCGTGAAGGTG
CTGATGAGCGGGCTCGACTACGAGCGCGCGGTGCTGGCGGGCGGCCCGACCGGCATCATGGCGGCCTGCCTCGACGCGGT
GGTGCCGTACATCCACGACCGCAAGCAGTTCGGCCAGTCGATCGGCGAGTTCCAGCTGATCCAGGGCAAGGTGGCCGACA
TGTACACGAACTTCCAGGCCTGCCGCGCCTACCTCTACGCGGTGGGCCGCCATCTGGACGCGGCCGGCAGCCACGTGCGC
CAGGCGCGCAAGGACTGCGCCGGCGTGATCCTCTACACGGCCGAGCGCGCCACCTGGATGGCGGGCGAGGCGATCCAGAT
CCTCGGCGGCAACGGCTACATCAACGAATATCCGGTGGGCCGGCTCTGGCGCGATGCCAAGCTCTACGAGATCGGCGCGG
GCACGAGCGAAATCCGCCGCATGCTGATCGGCCGCGAACTGTTCGCCGAGACGGCGTAA

Upstream 100 bases:

>100_bases
TCGTTCATTCGACCGGCGCCCGGGCAATTCTGAGCAAAACTCAGATCGATGTGCCGCACCGGCTCGGCCGACCGCACTTT
CTGGAATCGGAGGAGGAGAC

Downstream 100 bases:

>100_bases
GCGCCGCGCGGAGCCGACACGATGCCGATCCTCGAATCGAAACTGAACCCCCGCTCCGACGAATTCCGCGCCAACGCGGC
CGCGCTCGACGCGCTGGTGG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSNLPGVQFMLGEDIEMLRDAIATFAAKEIAPRAAEIDRTDQFPMDLWRKFGELGVLGMTVGEEYGGANLGYTAHMVAME
EISRASASVGLSYGAHSNLCVNQIHRNGSEAQKRRYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADRRGSHYVLNGTK
MWITNGPDCDTLVVYAKTDPEAGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFQDVEVPEENVLGEVGSGVKV
LMSGLDYERAVLAGGPTGIMAACLDAVVPYIHDRKQFGQSIGEFQLIQGKVADMYTNFQACRAYLYAVGRHLDAAGSHVR
QARKDCAGVILYTAERATWMAGEAIQILGGNGYINEYPVGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETA

Sequences:

>Translated_392_residues
MSNLPGVQFMLGEDIEMLRDAIATFAAKEIAPRAAEIDRTDQFPMDLWRKFGELGVLGMTVGEEYGGANLGYTAHMVAME
EISRASASVGLSYGAHSNLCVNQIHRNGSEAQKRRYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADRRGSHYVLNGTK
MWITNGPDCDTLVVYAKTDPEAGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFQDVEVPEENVLGEVGSGVKV
LMSGLDYERAVLAGGPTGIMAACLDAVVPYIHDRKQFGQSIGEFQLIQGKVADMYTNFQACRAYLYAVGRHLDAAGSHVR
QARKDCAGVILYTAERATWMAGEAIQILGGNGYINEYPVGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETA
>Mature_391_residues
SNLPGVQFMLGEDIEMLRDAIATFAAKEIAPRAAEIDRTDQFPMDLWRKFGELGVLGMTVGEEYGGANLGYTAHMVAMEE
ISRASASVGLSYGAHSNLCVNQIHRNGSEAQKRRYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADRRGSHYVLNGTKM
WITNGPDCDTLVVYAKTDPEAGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFQDVEVPEENVLGEVGSGVKVL
MSGLDYERAVLAGGPTGIMAACLDAVVPYIHDRKQFGQSIGEFQLIQGKVADMYTNFQACRAYLYAVGRHLDAAGSHVRQ
ARKDCAGVILYTAERATWMAGEAIQILGGNGYINEYPVGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=384, Percent_Identity=61.9791666666667, Blast_Score=494, Evalue=1e-140,
Organism=Homo sapiens, GI226958414, Length=379, Percent_Identity=60.9498680738786, Blast_Score=469, Evalue=1e-132,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=39.6825396825397, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=34.2245989304813, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI21361497, Length=382, Percent_Identity=36.9109947643979, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=36.0103626943005, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI187960098, Length=384, Percent_Identity=35.4166666666667, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=31.266149870801, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=37.3177842565598, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=37.3177842565598, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=30.7291666666667, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=34.8167539267016, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=35.9550561797753, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=27.5261324041812, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=27.5261324041812, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI38505218, Length=285, Percent_Identity=23.5087719298246, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87081958, Length=390, Percent_Identity=30.2564102564103, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1786223, Length=385, Percent_Identity=27.7922077922078, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI87081702, Length=332, Percent_Identity=24.3975903614458, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082384, Length=258, Percent_Identity=27.5193798449612, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=384, Percent_Identity=60.15625, Blast_Score=472, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=33.7765957446808, Blast_Score=237, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=389, Percent_Identity=34.1902313624679, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17570075, Length=392, Percent_Identity=34.1836734693878, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17534899, Length=390, Percent_Identity=34.1025641025641, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=31.331592689295, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17533517, Length=387, Percent_Identity=31.7829457364341, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=38.1118881118881, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=33.1444759206799, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=38.5281385281385, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=33.2116788321168, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17534353, Length=383, Percent_Identity=30.5483028720627, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=35.3356890459364, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=29.4429708222812, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=28.4210526315789, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=28.8065843621399, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=22.2996515679443, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=281, Percent_Identity=27.0462633451957, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=281, Percent_Identity=27.0462633451957, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=62.4352331606218, Blast_Score=476, Evalue=1e-134,
Organism=Drosophila melanogaster, GI21356377, Length=382, Percent_Identity=40.3141361256544, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=38.1578947368421, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24666513, Length=384, Percent_Identity=33.8541666666667, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24660351, Length=389, Percent_Identity=34.4473007712082, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI281363737, Length=356, Percent_Identity=34.2696629213483, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19920834, Length=392, Percent_Identity=32.3979591836735, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 42585; Mature: 42454

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLPGVQFMLGEDIEMLRDAIATFAAKEIAPRAAEIDRTDQFPMDLWRKFGELGVLGMT
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHCCCEEEEE
VGEEYGGANLGYTAHMVAMEEISRASASVGLSYGAHSNLCVNQIHRNGSEAQKRRYLPKL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
ISGEHVGALAMSEPNAGSDVVSMKLRADRRGSHYVLNGTKMWITNGPDCDTLVVYAKTDP
HCCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEEECEEEEEECCCCCCEEEEEEECCC
EAGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFQDVEVPEENVLGEVGSGVKV
CCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCCHHH
LMSGLDYERAVLAGGPTGIMAACLDAVVPYIHDRKQFGQSIGEFQLIQGKVADMYTNFQA
HHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHH
CRAYLYAVGRHLDAAGSHVRQARKDCAGVILYTAERATWMAGEAIQILGGNGYINEYPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEECCCEEEEECCCCCCCCCCCC
RLWRDAKLYEIGAGTSEIRRMLIGRELFAETA
HHHCCCEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNLPGVQFMLGEDIEMLRDAIATFAAKEIAPRAAEIDRTDQFPMDLWRKFGELGVLGMT
CCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHCCCEEEEE
VGEEYGGANLGYTAHMVAMEEISRASASVGLSYGAHSNLCVNQIHRNGSEAQKRRYLPKL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
ISGEHVGALAMSEPNAGSDVVSMKLRADRRGSHYVLNGTKMWITNGPDCDTLVVYAKTDP
HCCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEEECEEEEEECCCCCCEEEEEEECCC
EAGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFQDVEVPEENVLGEVGSGVKV
CCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCCHHH
LMSGLDYERAVLAGGPTGIMAACLDAVVPYIHDRKQFGQSIGEFQLIQGKVADMYTNFQA
HHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHH
CRAYLYAVGRHLDAAGSHVRQARKDCAGVILYTAERATWMAGEAIQILGGNGYINEYPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEECCCEEEEECCCCCCCCCCCC
RLWRDAKLYEIGAGTSEIRRMLIGRELFAETA
HHHCCCEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]