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The map label for this gene is pnuC [H]

Identifier: 238024517

GI number: 238024517

Start: 1433595

End: 1434206

Strand: Reverse

Name: pnuC [H]

Synonym: bglu_2g11230

Alternate gene names: 238024517

Gene position: 1434206-1433595 (Counterclockwise)

Preceding gene: 238024518

Following gene: 238024516

Centisome position: 50.73

GC content: 72.88

Gene sequence:

>612_bases
ATGTCCCCCCTCGAAATCACCGGCGTGATCGTGAGCGCGCTGGCGATCTGGCTGGCCGCGCGGCGCAGCATGCTGTGCTG
GCCGGTCGGGCTCGCCTCGGTCGCGCTCTACGCGTGGATCTTCTTCGATGCGCGGCTCTACTCGGACATGCTGCTGCAGG
GCGCGTTCGCGCTGCTGCAGCTGTACGGCTGGTACGGCTGGCTGATGCAGCGGCGCGAGCGCGCCGGCGAGCCGGTGGCG
CCGCAGCGCGGGGTGGGGCTGCGCCGGCTCGCGCCGGGGCTGGCCGCGGCCGTGGTGCTGAGCGCGCTGCTGGGCGGCGC
GATGGCGCGCTGGACCGACGCCTCGCTGCCCTACGTCGACGCCACGCTGACCGCGTTCAGCCTGGTCGCGCAGTACTGGA
CCGCGCGGCGCTATATTGCGTCATGGCAGCTCTGGTGCGTGGTCGATACGGTCTATGTCGGCATGTTCGTGTTCAAGGCG
CTCTACCTGACGGCCGGGCTCTACGCGCTGTTCGTGGTGCTCGCCGGGATCGGCTGGCGCGACTGGGCGCGCGCGCTGGC
CCGCGCCGATGCCGCGGGCGCAGCCGCGCTGCGGCCCGACGGCAGGCCATGA

Upstream 100 bases:

>100_bases
GGCGACGCCTACCTGTTCCTCGGCGCGCCGCGCACGGCCCGGCTCTCGGTCACCTGCGACTTCTGATCCGGCCCGCCACG
TTCTCCGGAGACGTCAACCC

Downstream 100 bases:

>100_bases
GCGCCCCGTTTTCCGGAGACCCGCTGGTGACGTCCGATTCCCGCTCCGATGCCGATTGCGCGGCCGATCGCCGTGGCTCG
CCCGCGCCGCGCGCCGCGCG

Product: Nicotinamide mononucleotide transporter PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSPLEITGVIVSALAIWLAARRSMLCWPVGLASVALYAWIFFDARLYSDMLLQGAFALLQLYGWYGWLMQRRERAGEPVA
PQRGVGLRRLAPGLAAAVVLSALLGGAMARWTDASLPYVDATLTAFSLVAQYWTARRYIASWQLWCVVDTVYVGMFVFKA
LYLTAGLYALFVVLAGIGWRDWARALARADAAGAAALRPDGRP

Sequences:

>Translated_203_residues
MSPLEITGVIVSALAIWLAARRSMLCWPVGLASVALYAWIFFDARLYSDMLLQGAFALLQLYGWYGWLMQRRERAGEPVA
PQRGVGLRRLAPGLAAAVVLSALLGGAMARWTDASLPYVDATLTAFSLVAQYWTARRYIASWQLWCVVDTVYVGMFVFKA
LYLTAGLYALFVVLAGIGWRDWARALARADAAGAAALRPDGRP
>Mature_202_residues
SPLEITGVIVSALAIWLAARRSMLCWPVGLASVALYAWIFFDARLYSDMLLQGAFALLQLYGWYGWLMQRRERAGEPVAP
QRGVGLRRLAPGLAAAVVLSALLGGAMARWTDASLPYVDATLTAFSLVAQYWTARRYIASWQLWCVVDTVYVGMFVFKAL
YLTAGLYALFVVLAGIGWRDWARALARADAAGAAALRPDGRP

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 22280; Mature: 22149

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLEITGVIVSALAIWLAARRSMLCWPVGLASVALYAWIFFDARLYSDMLLQGAFALLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGWYGWLMQRRERAGEPVAPQRGVGLRRLAPGLAAAVVLSALLGGAMARWTDASLPYVD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ATLTAFSLVAQYWTARRYIASWQLWCVVDTVYVGMFVFKALYLTAGLYALFVVLAGIGWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
DWARALARADAAGAAALRPDGRP
HHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SPLEITGVIVSALAIWLAARRSMLCWPVGLASVALYAWIFFDARLYSDMLLQGAFALLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGWYGWLMQRRERAGEPVAPQRGVGLRRLAPGLAAAVVLSALLGGAMARWTDASLPYVD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ATLTAFSLVAQYWTARRYIASWQLWCVVDTVYVGMFVFKALYLTAGLYALFVVLAGIGWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
DWARALARADAAGAAALRPDGRP
HHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]