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The map label for this gene is fadD [H]

Identifier: 238024454

GI number: 238024454

Start: 1340203

End: 1342086

Strand: Reverse

Name: fadD [H]

Synonym: bglu_2g10500

Alternate gene names: 238024454

Gene position: 1342086-1340203 (Counterclockwise)

Preceding gene: 238024455

Following gene: 238024453

Centisome position: 47.47

GC content: 70.33

Gene sequence:

>1884_bases
TTGGAAACGGACCACCGCCTTGGATTGGCGAACCCAGCCGGATACCGGCATGTCGCCATCCAGGCCAGCGCACCGCATGT
CGAGCGTCGCGGCGAGTGCTGGTACCTGCGCGCGAGCGCGCCGCTCGGCGCTTATCCGTCGCGCTTCACGGACCGGCTCG
TCAGTGGCGCGCAAGCGCACCCCGACCGGCTGCTGGTGGCGCAGCGCGACGCGCAAGGCGCCTGGCGCGGCGTGAGCTAC
GCGCAGATGCTCGAGAATGCACGCGCGATCGGCGAGGCCCTGCTCGGCCGCGGCCTGAGCGCCGAGCGGCCGCTCGCGAT
CCTGTCCGGCAACAGCATCGAGCACCTGCAAATGGCACTGGGCGCGATGTGGGCGGGCATCCCCTATGCGCCGGTCTCGC
CCGCCTATTCGCTGATCTCGGGCGATTTCGGCAAGCTGCGCCACGTGTTCGAGCTGCTCACGCCGGGCCTGGTGTTCGCC
GACGACCTCGCGGCCTATGCGGCCGGCCTCGACGCGGCCTTGCCGCGCGACGTCGAGCGGGTCGGCGTGGCGCCCGGCGC
GGGCGGCGCCACGCCGTTTGCGGCGCTGCTCGACACGCTCCCGCGCGACGTCGATGCGGCGCACGCACGGGTGGATGGCG
ACACGATCGCGAAATTTCTGTTCACCTCCGGCTCGACGCGTCTGCCGAAAGCGGTGCCGACCACGCACCGGATGCTGTGC
GCCAATCAGCAGATGCTGCTCGAAACCTTTCCGCAGTTCGGTATCGAGCCGCCGGTGCTGGTCGACTGGCTGCCGTGGAA
CCACACGTTCGGCGGCAGCCATAACGTCGGCATCGTGCTGTACAACGGCGGCACGCTGTATATCGACGGCGGCAAGCCGG
TGGCGGGCAAGTTCGACGAGACGGTGCGCAATCTGCACGAGATCGCGCCCACCGTGTTCTTCAACGTGCCCAAGGGCTGG
GAGGAACTGACGGCCGCGCTGGAAGCCGATGCGGCGCTGCGCGAGCGCTTTTTCTCGCGCGTGAAGCTGTACTTCTTTGC
CGGCGCGGGCTTGTCCCAGGCCGCCTGGGACCGGCTCGAGCGCGTGACGCTGGCGCATTGCGGCGAGCGCATCCGCATCA
TGGCGGGGCTCGGCATGACGGAGACCGCCCCCTCGTGCCTGTTCACCACCGGCCCGGTATCGGGCGCGGGGTACATCGGC
CTGCCCGCGCCGGGCTGCGAGGCGAAGATCGCGCCGGTCGACGGCAAGTTCGAGGTGCGTTTCCGCGGGCCGAACGTGAT
GCGCGGCTACTGGCGCATGCCCACCGCCAACGCGGAGATCTTCGACGACGAAGGCTACTACCGCAGCGGCGACGCCGTGC
GTTTCGTCGACAGCGAGCGGCCGGAACTGGGGCTCGCCTTCGACGGGCGCATCGCCGAGGACTTCAAGCTCGGCTCGGGC
ACCTTCGTGAGCGTCGGGCCGATGCGCGCGCGCATCATCTCGGAGGGCGCGCCCTATGTGCAGGACGCGGTCATCACCGG
CATGAATCGCGACGAAGTGGGCGCCATGGTGTTTCCCCGTGTCGACGCCTGCCGCTCGCTCGCGGGCCTGGGCCGGGACG
CGGGCGTGGCGGACGTGCTCAACGCGCCGGCGGTGCGGGCGTTCTTCGCGGCGCTGCTCGACAAGCTCAACCAGCACGCC
ACCGGCAGCGCGACGTTGATTGCCAGGCTGCGGCTGCTGGCGGTGCCGCCCTCGCTCGATCTCGGCGAGGTGACCGACAA
AGGCTCGATCAACCAGCGCGCGGTGCTCCAGCATCGCGCCGCGCTGGTCGACGCCATGCATGACGGCGGCGATCCGGAGG
TCATCGAGGCGCGCGAGCGCCGCGGCCAGGCGGCACGACCATGA

Upstream 100 bases:

>100_bases
GCGGCGCCCGCGCCGCGAGCGAGCATGCCATGCCGCGCGCCCCGCCGCGATCGCAGCGACGCGACGGGGCAAACGCCGCG
GCCCAACCAGGAGACAGGCC

Downstream 100 bases:

>100_bases
CGGCTTCGGCGCGGCGCGGTTCGGCGCCGGCGCCTTGCCGGCCGCGGCCTGCTCGCGCCCGGCGGTAGCGCGGGGCGCTG
GCGCCCCGCCCCGGCCGGCA

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; Acyl-CoA synthetase [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
METDHRLGLANPAGYRHVAIQASAPHVERRGECWYLRASAPLGAYPSRFTDRLVSGAQAHPDRLLVAQRDAQGAWRGVSY
AQMLENARAIGEALLGRGLSAERPLAILSGNSIEHLQMALGAMWAGIPYAPVSPAYSLISGDFGKLRHVFELLTPGLVFA
DDLAAYAAGLDAALPRDVERVGVAPGAGGATPFAALLDTLPRDVDAAHARVDGDTIAKFLFTSGSTRLPKAVPTTHRMLC
ANQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIVLYNGGTLYIDGGKPVAGKFDETVRNLHEIAPTVFFNVPKGW
EELTAALEADAALRERFFSRVKLYFFAGAGLSQAAWDRLERVTLAHCGERIRIMAGLGMTETAPSCLFTTGPVSGAGYIG
LPAPGCEAKIAPVDGKFEVRFRGPNVMRGYWRMPTANAEIFDDEGYYRSGDAVRFVDSERPELGLAFDGRIAEDFKLGSG
TFVSVGPMRARIISEGAPYVQDAVITGMNRDEVGAMVFPRVDACRSLAGLGRDAGVADVLNAPAVRAFFAALLDKLNQHA
TGSATLIARLRLLAVPPSLDLGEVTDKGSINQRAVLQHRAALVDAMHDGGDPEVIEARERRGQAARP

Sequences:

>Translated_627_residues
METDHRLGLANPAGYRHVAIQASAPHVERRGECWYLRASAPLGAYPSRFTDRLVSGAQAHPDRLLVAQRDAQGAWRGVSY
AQMLENARAIGEALLGRGLSAERPLAILSGNSIEHLQMALGAMWAGIPYAPVSPAYSLISGDFGKLRHVFELLTPGLVFA
DDLAAYAAGLDAALPRDVERVGVAPGAGGATPFAALLDTLPRDVDAAHARVDGDTIAKFLFTSGSTRLPKAVPTTHRMLC
ANQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIVLYNGGTLYIDGGKPVAGKFDETVRNLHEIAPTVFFNVPKGW
EELTAALEADAALRERFFSRVKLYFFAGAGLSQAAWDRLERVTLAHCGERIRIMAGLGMTETAPSCLFTTGPVSGAGYIG
LPAPGCEAKIAPVDGKFEVRFRGPNVMRGYWRMPTANAEIFDDEGYYRSGDAVRFVDSERPELGLAFDGRIAEDFKLGSG
TFVSVGPMRARIISEGAPYVQDAVITGMNRDEVGAMVFPRVDACRSLAGLGRDAGVADVLNAPAVRAFFAALLDKLNQHA
TGSATLIARLRLLAVPPSLDLGEVTDKGSINQRAVLQHRAALVDAMHDGGDPEVIEARERRGQAARP
>Mature_627_residues
METDHRLGLANPAGYRHVAIQASAPHVERRGECWYLRASAPLGAYPSRFTDRLVSGAQAHPDRLLVAQRDAQGAWRGVSY
AQMLENARAIGEALLGRGLSAERPLAILSGNSIEHLQMALGAMWAGIPYAPVSPAYSLISGDFGKLRHVFELLTPGLVFA
DDLAAYAAGLDAALPRDVERVGVAPGAGGATPFAALLDTLPRDVDAAHARVDGDTIAKFLFTSGSTRLPKAVPTTHRMLC
ANQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIVLYNGGTLYIDGGKPVAGKFDETVRNLHEIAPTVFFNVPKGW
EELTAALEADAALRERFFSRVKLYFFAGAGLSQAAWDRLERVTLAHCGERIRIMAGLGMTETAPSCLFTTGPVSGAGYIG
LPAPGCEAKIAPVDGKFEVRFRGPNVMRGYWRMPTANAEIFDDEGYYRSGDAVRFVDSERPELGLAFDGRIAEDFKLGSG
TFVSVGPMRARIISEGAPYVQDAVITGMNRDEVGAMVFPRVDACRSLAGLGRDAGVADVLNAPAVRAFFAALLDKLNQHA
TGSATLIARLRLLAVPPSLDLGEVTDKGSINQRAVLQHRAALVDAMHDGGDPEVIEARERRGQAARP

Specific function: Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Membrane; Peripheral membrane protein (Potential). Note=Partially membrane-associated (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI40807491, Length=500, Percent_Identity=23, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788107, Length=258, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17556552, Length=457, Percent_Identity=25.164113785558, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17564090, Length=436, Percent_Identity=23.394495412844, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 67341; Mature: 67341

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METDHRLGLANPAGYRHVAIQASAPHVERRGECWYLRASAPLGAYPSRFTDRLVSGAQAH
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCC
PDRLLVAQRDAQGAWRGVSYAQMLENARAIGEALLGRGLSAERPLAILSGNSIEHLQMAL
CCEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHH
GAMWAGIPYAPVSPAYSLISGDFGKLRHVFELLTPGLVFADDLAAYAAGLDAALPRDVER
HHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHCCCCCHHH
VGVAPGAGGATPFAALLDTLPRDVDAAHARVDGDTIAKFLFTSGSTRLPKAVPTTHRMLC
HCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ANQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIVLYNGGTLYIDGGKPVAGKFDE
CCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCHHH
TVRNLHEIAPTVFFNVPKGWEELTAALEADAALRERFFSRVKLYFFAGAGLSQAAWDRLE
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHH
RVTLAHCGERIRIMAGLGMTETAPSCLFTTGPVSGAGYIGLPAPGCEAKIAPVDGKFEVR
HHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCEEECCCCEEEEE
FRGPNVMRGYWRMPTANAEIFDDEGYYRSGDAVRFVDSERPELGLAFDGRIAEDFKLGSG
ECCCCEEEEEEECCCCCCEEECCCCCEECCCEEEEECCCCCCEEEEECCCCCCCEECCCC
TFVSVGPMRARIISEGAPYVQDAVITGMNRDEVGAMVFPRVDACRSLAGLGRDAGVADVL
CEEEECCHHHHHHHCCCCHHHHHHHCCCCHHHCCEEECCCHHHHHHHHHCCCCCCHHHHH
NAPAVRAFFAALLDKLNQHATGSATLIARLRLLAVPPSLDLGEVTDKGSINQRAVLQHRA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHH
ALVDAMHDGGDPEVIEARERRGQAARP
HHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
METDHRLGLANPAGYRHVAIQASAPHVERRGECWYLRASAPLGAYPSRFTDRLVSGAQAH
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCC
PDRLLVAQRDAQGAWRGVSYAQMLENARAIGEALLGRGLSAERPLAILSGNSIEHLQMAL
CCEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHH
GAMWAGIPYAPVSPAYSLISGDFGKLRHVFELLTPGLVFADDLAAYAAGLDAALPRDVER
HHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHCCCCCHHH
VGVAPGAGGATPFAALLDTLPRDVDAAHARVDGDTIAKFLFTSGSTRLPKAVPTTHRMLC
HCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ANQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIVLYNGGTLYIDGGKPVAGKFDE
CCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCHHH
TVRNLHEIAPTVFFNVPKGWEELTAALEADAALRERFFSRVKLYFFAGAGLSQAAWDRLE
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHH
RVTLAHCGERIRIMAGLGMTETAPSCLFTTGPVSGAGYIGLPAPGCEAKIAPVDGKFEVR
HHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCEEECCCCEEEEE
FRGPNVMRGYWRMPTANAEIFDDEGYYRSGDAVRFVDSERPELGLAFDGRIAEDFKLGSG
ECCCCEEEEEEECCCCCCEEECCCCCEECCCEEEEECCCCCCEEEEECCCCCCCEECCCC
TFVSVGPMRARIISEGAPYVQDAVITGMNRDEVGAMVFPRVDACRSLAGLGRDAGVADVL
CEEEECCHHHHHHHCCCCHHHHHHHCCCCHHHCCEEECCCHHHHHHHHHCCCCCCHHHHH
NAPAVRAFFAALLDKLNQHATGSATLIARLRLLAVPPSLDLGEVTDKGSINQRAVLQHRA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHH
ALVDAMHDGGDPEVIEARERRGQAARP
HHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]