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The map label for this gene is ttdR [H]

Identifier: 238024452

GI number: 238024452

Start: 1337740

End: 1338660

Strand: Reverse

Name: ttdR [H]

Synonym: bglu_2g10480

Alternate gene names: 238024452

Gene position: 1338660-1337740 (Counterclockwise)

Preceding gene: 238024453

Following gene: 238024451

Centisome position: 47.35

GC content: 71.66

Gene sequence:

>921_bases
ATGCTTCAACTCGAAGACATGCAACTGCTGCGCGCGCTGGGCGCCTCGCCGTCGCTCGCGGCCGCGGCACGGCTGCTGGA
CCTGACGCCGCCCGCCGTCACGGTACGGCTCCGGCGCATCGAGCAACGGGTGGGCGTGAGCCTCGCGACGCGGGCGGCGA
GGGGCATTTCCTTGACCGACGAGGGACAGCGCCTGATCCAGGAGGCCATCGACATCCTCGAGCGGATCGAGTCGCTTCCG
TCCCGCCTCTCGGACCAAGCCAACGGCGTGAGCGGCCACCTGCGCGTGGTGGCGCCGTTCGGGTTCGGGCGCGCCTACGT
GGCGCCGCTGATCCGCAGCCTGCACCGCTCGCATCCCCGGCTCGCGGTCTCGCTGATCCTGGTGGAAAGTCCGCTGGCCG
CGGCATCGGGTGCCGATGTGGTGATCTCCATCGGCCCCATCAAGGGCTCCTCGTGGGTCGGACATTGGCTGGCGCCGAAC
GAGCGCCTGCTGTGCGCCGGCCCCGCCCTGGCGCGCAGCCTGTCCGAACTCGGGCATCCGTCCGAACTCGGCCGTTACCC
GTACCTCGCGCTGCGCGAGAACGACGAGGAAGTCACCCGGCTGCGCTTCACACAGCACGACGCCGCGGGCAGGCGCGCGG
GCAAGGCCGTGACGGTCAGGCTGACGAGCGTCCTGTCGTCGAACGACGGCACCGTGGTGAGGGACTGGGCGGCGGACGGG
CTCGGCGTCGTCGCCCGCTCCGAATGGGACTGCGTGCGGCTGCTCGCCGAAGGCAGGCTGGTGCGCGTCCTGCCGGCATG
GCGGCTCGATCCGGCGCCCGTGATCGCGCTCACGCCCACCCGCCAGGGGCTGACGATTCGTCAGCGGGTATTCCTCGATG
CGGCGAAGCGCGCCTTCGACCCCGTGCCGTGGCGGGCTTGA

Upstream 100 bases:

>100_bases
GCCGAACGGCCAGCGCCGGCGCGGCCGGCCCGGCGCCAATCCAGGAAAAGATATTTTGGCCTGTCTACTATGGGATGAGC
GAATCATCGATGGGGGGTGA

Downstream 100 bases:

>100_bases
CCCGGCCGGCCGCCGAGGCCCGCCTCGCGAAGCCGCGAACCTCGCGGCACCCGGCGCCGCTCGCGCGGTGCGCCGCGCCG
TAGGCGACGCGCATGCCGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLQLEDMQLLRALGASPSLAAAARLLDLTPPAVTVRLRRIEQRVGVSLATRAARGISLTDEGQRLIQEAIDILERIESLP
SRLSDQANGVSGHLRVVAPFGFGRAYVAPLIRSLHRSHPRLAVSLILVESPLAAASGADVVISIGPIKGSSWVGHWLAPN
ERLLCAGPALARSLSELGHPSELGRYPYLALRENDEEVTRLRFTQHDAAGRRAGKAVTVRLTSVLSSNDGTVVRDWAADG
LGVVARSEWDCVRLLAEGRLVRVLPAWRLDPAPVIALTPTRQGLTIRQRVFLDAAKRAFDPVPWRA

Sequences:

>Translated_306_residues
MLQLEDMQLLRALGASPSLAAAARLLDLTPPAVTVRLRRIEQRVGVSLATRAARGISLTDEGQRLIQEAIDILERIESLP
SRLSDQANGVSGHLRVVAPFGFGRAYVAPLIRSLHRSHPRLAVSLILVESPLAAASGADVVISIGPIKGSSWVGHWLAPN
ERLLCAGPALARSLSELGHPSELGRYPYLALRENDEEVTRLRFTQHDAAGRRAGKAVTVRLTSVLSSNDGTVVRDWAADG
LGVVARSEWDCVRLLAEGRLVRVLPAWRLDPAPVIALTPTRQGLTIRQRVFLDAAKRAFDPVPWRA
>Mature_306_residues
MLQLEDMQLLRALGASPSLAAAARLLDLTPPAVTVRLRRIEQRVGVSLATRAARGISLTDEGQRLIQEAIDILERIESLP
SRLSDQANGVSGHLRVVAPFGFGRAYVAPLIRSLHRSHPRLAVSLILVESPLAAASGADVVISIGPIKGSSWVGHWLAPN
ERLLCAGPALARSLSELGHPSELGRYPYLALRENDEEVTRLRFTQHDAAGRRAGKAVTVRLTSVLSSNDGTVVRDWAADG
LGVVARSEWDCVRLLAEGRLVRVLPAWRLDPAPVIALTPTRQGLTIRQRVFLDAAKRAFDPVPWRA

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=264, Percent_Identity=32.5757575757576, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87081978, Length=300, Percent_Identity=31.6666666666667, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=24.5033112582781, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789639, Length=305, Percent_Identity=22.9508196721311, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=25.3333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787589, Length=301, Percent_Identity=25.2491694352159, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33219; Mature: 33219

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLEDMQLLRALGASPSLAAAARLLDLTPPAVTVRLRRIEQRVGVSLATRAARGISLTD
CCCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCH
EGQRLIQEAIDILERIESLPSRLSDQANGVSGHLRVVAPFGFGRAYVAPLIRSLHRSHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
LAVSLILVESPLAAASGADVVISIGPIKGSSWVGHWLAPNERLLCAGPALARSLSELGHP
EEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEEECHHHHHHHHHCCCH
SELGRYPYLALRENDEEVTRLRFTQHDAAGRRAGKAVTVRLTSVLSSNDGTVVRDWAADG
HHHCCCCEEEEECCCHHHHHHHHHHCCHHHHCCCCEEEEEEEEHHCCCCCCEEEECCCCC
LGVVARSEWDCVRLLAEGRLVRVLPAWRLDPAPVIALTPTRQGLTIRQRVFLDAAKRAFD
CCEEECCCHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCC
PVPWRA
CCCCCC
>Mature Secondary Structure
MLQLEDMQLLRALGASPSLAAAARLLDLTPPAVTVRLRRIEQRVGVSLATRAARGISLTD
CCCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCH
EGQRLIQEAIDILERIESLPSRLSDQANGVSGHLRVVAPFGFGRAYVAPLIRSLHRSHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
LAVSLILVESPLAAASGADVVISIGPIKGSSWVGHWLAPNERLLCAGPALARSLSELGHP
EEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEEECHHHHHHHHHCCCH
SELGRYPYLALRENDEEVTRLRFTQHDAAGRRAGKAVTVRLTSVLSSNDGTVVRDWAADG
HHHCCCCEEEEECCCHHHHHHHHHHCCHHHHCCCCEEEEEEEEHHCCCCCCEEEECCCCC
LGVVARSEWDCVRLLAEGRLVRVLPAWRLDPAPVIALTPTRQGLTIRQRVFLDAAKRAFD
CCEEECCCHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCC
PVPWRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]