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The map label for this gene is phoP [H]

Identifier: 238024425

GI number: 238024425

Start: 1302227

End: 1303003

Strand: Reverse

Name: phoP [H]

Synonym: bglu_2g10190

Alternate gene names: 238024425

Gene position: 1303003-1302227 (Counterclockwise)

Preceding gene: 238024430

Following gene: 238024424

Centisome position: 46.09

GC content: 66.8

Gene sequence:

>777_bases
ATGGAGATTCGATGGAGAACGAAAAAATACCCGGCCGCCATGCTTGATTCGACGCTGCCAGCCAATGCTGAGCCAAGCAC
TCAGGCCTTGATCCTGATTGCCGAGGACGAGCCCGAAATCGCCGACATCGTGGCGGCCTACCTGACGCGTTCGGGCCTGC
GCAGCGTGCAGGCGACTGATGGCCGGCAGGCGCTCGAGCTTCACGAGCGCCTGAAGCCCGACCTGGTCCTGCTGGACGTG
CAGATGCCCTGCCTGGACGGCTGGCAGGTGCTCACCGAAATCCGCCGCCGCGGCGACACGCCCGTCATCATGCTGACGGC
GATGGACCAGGACATCGACAAGCTGATGGGGCTGCGCATCGGAGCCGACGACTACGTCGTCAAGCCTTTCAACCCGGCGG
AGGTGGTGGCGCGCACGCAGGCGGTGCTGCGCCGTTCGATGGCGCGGGGCGAGCGCGAAGAGCAGCGCGTGCTGCGCGCG
GCGCCGTTCGAAATCGACCTGGACCACCATGAGGCGACCGTCGAGGTCGGCAAGCAGCGCCACGCGCTGAGCTTGACGCT
GACCGAGTTCAAGCTGCTGGTGCAACTGGCGCGTGCGCCCAAGCGCGTGTTCAGCCGCGCGGAACTGCTGGCGACCTGCC
TGCCGGAAGGCGATACCCTGGAGCGCACGGTGGACAGCCACATCAGCAAGCTGCGCAAGAAGCTGGAGGACCGGGGGGTC
ACCGGCATCCCGGTCGGCATTCGCGGGGTGGGCTACCGGCTCTGGAGCACCGAATGA

Upstream 100 bases:

>100_bases
TGATTCGATCTTCATGGAACTCCTTCGGAAACAGGCCGTCGATGGCCGGCGAGACGGTCGGGAGTCTGAATCTGGACGAT
GGTGTTTCGTCCGAGCTATG

Downstream 100 bases:

>100_bases
AACTGGTTGGATTGAGCCGCCAGATCGCGCTGACGATGATGGCGATGGCGTTTGGCGTCACCCTGCTGTTCCTGCTGACC
TCCTATGCCTTCTATTTCTT

Product: two component response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MEIRWRTKKYPAAMLDSTLPANAEPSTQALILIAEDEPEIADIVAAYLTRSGLRSVQATDGRQALELHERLKPDLVLLDV
QMPCLDGWQVLTEIRRRGDTPVIMLTAMDQDIDKLMGLRIGADDYVVKPFNPAEVVARTQAVLRRSMARGEREEQRVLRA
APFEIDLDHHEATVEVGKQRHALSLTLTEFKLLVQLARAPKRVFSRAELLATCLPEGDTLERTVDSHISKLRKKLEDRGV
TGIPVGIRGVGYRLWSTE

Sequences:

>Translated_258_residues
MEIRWRTKKYPAAMLDSTLPANAEPSTQALILIAEDEPEIADIVAAYLTRSGLRSVQATDGRQALELHERLKPDLVLLDV
QMPCLDGWQVLTEIRRRGDTPVIMLTAMDQDIDKLMGLRIGADDYVVKPFNPAEVVARTQAVLRRSMARGEREEQRVLRA
APFEIDLDHHEATVEVGKQRHALSLTLTEFKLLVQLARAPKRVFSRAELLATCLPEGDTLERTVDSHISKLRKKLEDRGV
TGIPVGIRGVGYRLWSTE
>Mature_258_residues
MEIRWRTKKYPAAMLDSTLPANAEPSTQALILIAEDEPEIADIVAAYLTRSGLRSVQATDGRQALELHERLKPDLVLLDV
QMPCLDGWQVLTEIRRRGDTPVIMLTAMDQDIDKLMGLRIGADDYVVKPFNPAEVVARTQAVLRRSMARGEREEQRVLRA
APFEIDLDHHEATVEVGKQRHALSLTLTEFKLLVQLARAPKRVFSRAELLATCLPEGDTLERTVDSHISKLRKKLEDRGV
TGIPVGIRGVGYRLWSTE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=39.5652173913043, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=39.1304347826087, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=35.6828193832599, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.6086956521739, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789809, Length=212, Percent_Identity=32.5471698113208, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=34.2222222222222, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=30.1724137931034, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.8017621145374, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=29.3333333333333, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=30.2631578947368, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787229, Length=212, Percent_Identity=31.6037735849057, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=31.7180616740088, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=33.7662337662338, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=35.3383458646617, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787487, Length=107, Percent_Identity=37.3831775700935, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29008; Mature: 29008

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRWRTKKYPAAMLDSTLPANAEPSTQALILIAEDEPEIADIVAAYLTRSGLRSVQATD
CCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
GRQALELHERLKPDLVLLDVQMPCLDGWQVLTEIRRRGDTPVIMLTAMDQDIDKLMGLRI
CHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCEE
GADDYVVKPFNPAEVVARTQAVLRRSMARGEREEQRVLRAAPFEIDLDHHEATVEVGKQR
CCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCHHHHHHCCCH
HALSLTLTEFKLLVQLARAPKRVFSRAELLATCLPEGDTLERTVDSHISKLRKKLEDRGV
HEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
TGIPVGIRGVGYRLWSTE
CCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MEIRWRTKKYPAAMLDSTLPANAEPSTQALILIAEDEPEIADIVAAYLTRSGLRSVQATD
CCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
GRQALELHERLKPDLVLLDVQMPCLDGWQVLTEIRRRGDTPVIMLTAMDQDIDKLMGLRI
CHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCEE
GADDYVVKPFNPAEVVARTQAVLRRSMARGEREEQRVLRAAPFEIDLDHHEATVEVGKQR
CCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCHHHHHHCCCH
HALSLTLTEFKLLVQLARAPKRVFSRAELLATCLPEGDTLERTVDSHISKLRKKLEDRGV
HEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
TGIPVGIRGVGYRLWSTE
CCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]