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The map label for this gene is fhuD [H]

Identifier: 238024385

GI number: 238024385

Start: 1213504

End: 1214472

Strand: Direct

Name: fhuD [H]

Synonym: bglu_2g09780

Alternate gene names: 238024385

Gene position: 1213504-1214472 (Clockwise)

Preceding gene: 238024384

Following gene: 238024386

Centisome position: 42.92

GC content: 76.26

Gene sequence:

>969_bases
ATGCCGCGCCCCGATCCGCAGCGCCGCCGCTGGCTCGCGCGCGGCGGCGCGTTCGGCCTGCTCGGCGCGCTGGCCTGGTG
CGCGCCGCTGCGCGCGGCGGCGCCGGCCGCCGCCGCGCCCGCCAGGTTCCCCACGCGCGTCGTCTCGATGAACTGGGAGC
TGACCGAGACGCTGCTCGCGCTCGGCGTGGTGCCGGTCGGCGTTTCGCTGCCCGACTGGTATCGCAGCTCGATCGTCGAG
CCGCCGCTGCCGCCGGGGGTGGCCGACATCGGCCTGCTGTACCAGCCCAACTTCGAGGTGCTGCTGGCGCTGCGGCCGGA
CCTGCTGGTGATCACGCCGGGCCACCTGCCGGCCCTGCGCACGCTGCAGCGCGTGGCGCCCACCATCACCCTGAGCCAGT
ACATGACGAGCGCGCAGCCGTACCGCGATCTCTGCGGCGAGACGGTCACGCTCGGCGCGCGGCTCGGGCGCACCGCGCGC
GCGCAGCAGCTGGTGGCCGAGGCGGCGCGCACCACCGAGGCGGTGCGCGCGCGGCTCGCGGCCCGGCCGGCGCTGCTGCG
CCATCCGCTGATCGTGGCCGAGCTGGTGGACGATCGCCATCTGCGCGTCTACGGCCGCGGCAGCCTGTTCGACGAGATGC
TCGCCAGGCTCGGCGCGGCCAATGCCGCGCATCCGCGCGACGGCGGCGCGGCATGGCCCACCCAGGCGGGCTATGCGCTG
GTGCCGCTGCAGCGGCTCGCCGAGGTGCCCGCGGCGAGCCTGCTGCTGGTCGGCCCGGTCAGGCCCGACGCGCGCCGCGG
GCTCGACGACAACGCGATCTGGCAGGCGCTGCCGGCGGTGCGCGAGCGGCGCGTCGCGACGCTGCCGGTGATCGCGCCTT
ACGGAGGACTGGTATCGATGCAACGCTTCGCCGGGGCGATCGAGGCGGCGCTGACGGCGATCGACGCGGGAGGGGGCGGT
GTTGCGTAA

Upstream 100 bases:

>100_bases
TCTACGGCGTGCCGATGGGCGTGATGACCGACCCGGTCGGCGGCCACCGCATCGGTTATCCGCGATGAGCCGGCCGCGTT
CCGTTCGGCGCGCGCGCGCC

Downstream 100 bases:

>100_bases
TCCCATGGCCTTGCCCCGTCACGCCGCGCCGCGCGAGTTCCGCTGGTGGCTGGTGGGCGCGCTGCTGGCCGTCTCGCTGC
TGCTCGCGGCGCTCGGCATC

Product: Fe3 -hydroxamate ABC transporter periplasmic component

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein D; Ferrichrome-binding periplasmic protein; Iron(III)-hydroxamate-binding protein fhuD [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPRPDPQRRRWLARGGAFGLLGALAWCAPLRAAAPAAAAPARFPTRVVSMNWELTETLLALGVVPVGVSLPDWYRSSIVE
PPLPPGVADIGLLYQPNFEVLLALRPDLLVITPGHLPALRTLQRVAPTITLSQYMTSAQPYRDLCGETVTLGARLGRTAR
AQQLVAEAARTTEAVRARLAARPALLRHPLIVAELVDDRHLRVYGRGSLFDEMLARLGAANAAHPRDGGAAWPTQAGYAL
VPLQRLAEVPAASLLLVGPVRPDARRGLDDNAIWQALPAVRERRVATLPVIAPYGGLVSMQRFAGAIEAALTAIDAGGGG
VA

Sequences:

>Translated_322_residues
MPRPDPQRRRWLARGGAFGLLGALAWCAPLRAAAPAAAAPARFPTRVVSMNWELTETLLALGVVPVGVSLPDWYRSSIVE
PPLPPGVADIGLLYQPNFEVLLALRPDLLVITPGHLPALRTLQRVAPTITLSQYMTSAQPYRDLCGETVTLGARLGRTAR
AQQLVAEAARTTEAVRARLAARPALLRHPLIVAELVDDRHLRVYGRGSLFDEMLARLGAANAAHPRDGGAAWPTQAGYAL
VPLQRLAEVPAASLLLVGPVRPDARRGLDDNAIWQALPAVRERRVATLPVIAPYGGLVSMQRFAGAIEAALTAIDAGGGG
VA
>Mature_321_residues
PRPDPQRRRWLARGGAFGLLGALAWCAPLRAAAPAAAAPARFPTRVVSMNWELTETLLALGVVPVGVSLPDWYRSSIVEP
PLPPGVADIGLLYQPNFEVLLALRPDLLVITPGHLPALRTLQRVAPTITLSQYMTSAQPYRDLCGETVTLGARLGRTARA
QQLVAEAARTTEAVRARLAARPALLRHPLIVAELVDDRHLRVYGRGSLFDEMLARLGAANAAHPRDGGAAWPTQAGYALV
PLQRLAEVPAASLLLVGPVRPDARRGLDDNAIWQALPAVRERRVATLPVIAPYGGLVSMQRFAGAIEAALTAIDAGGGGV
A

Specific function: Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of all iron(3+)-hydroxamate siderophores such as ferrich

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786346, Length=292, Percent_Identity=31.1643835616438, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008091
- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 34283; Mature: 34152

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPDPQRRRWLARGGAFGLLGALAWCAPLRAAAPAAAAPARFPTRVVSMNWELTETLLA
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHH
LGVVPVGVSLPDWYRSSIVEPPLPPGVADIGLLYQPNFEVLLALRPDLLVITPGHLPALR
HHHHHCCCCCCHHHHHCCCCCCCCCCHHHCCEEECCCCEEEEEECCCEEEECCCCCHHHH
TLQRVAPTITLSQYMTSAQPYRDLCGETVTLGARLGRTARAQQLVAEAARTTEAVRARLA
HHHHHHCHHHHHHHHHCCCHHHHHCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ARPALLRHPLIVAELVDDRHLRVYGRGSLFDEMLARLGAANAAHPRDGGAAWPTQAGYAL
HCHHHHHCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
VPLQRLAEVPAASLLLVGPVRPDARRGLDDNAIWQALPAVRERRVATLPVIAPYGGLVSM
HHHHHHHHCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHCCCEECCEECCCCHHHHH
QRFAGAIEAALTAIDAGGGGVA
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRPDPQRRRWLARGGAFGLLGALAWCAPLRAAAPAAAAPARFPTRVVSMNWELTETLLA
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHH
LGVVPVGVSLPDWYRSSIVEPPLPPGVADIGLLYQPNFEVLLALRPDLLVITPGHLPALR
HHHHHCCCCCCHHHHHCCCCCCCCCCHHHCCEEECCCCEEEEEECCCEEEECCCCCHHHH
TLQRVAPTITLSQYMTSAQPYRDLCGETVTLGARLGRTARAQQLVAEAARTTEAVRARLA
HHHHHHCHHHHHHHHHCCCHHHHHCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ARPALLRHPLIVAELVDDRHLRVYGRGSLFDEMLARLGAANAAHPRDGGAAWPTQAGYAL
HCHHHHHCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
VPLQRLAEVPAASLLLVGPVRPDARRGLDDNAIWQALPAVRERRVATLPVIAPYGGLVSM
HHHHHHHHCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHCCCEECCEECCCCHHHHH
QRFAGAIEAALTAIDAGGGGVA
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301821; 2823072; 8202364; 9278503; 7651325; 10742172 [H]