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The map label for this gene is aroE [H]

Identifier: 238024365

GI number: 238024365

Start: 1176986

End: 1177819

Strand: Direct

Name: aroE [H]

Synonym: bglu_2g09580

Alternate gene names: 238024365

Gene position: 1176986-1177819 (Clockwise)

Preceding gene: 238024364

Following gene: 238024366

Centisome position: 41.63

GC content: 71.1

Gene sequence:

>834_bases
ATGCGCGATACCTATGCCGTGATCGGCAACCCCATTGGCCATACCAAATCGCCGATGATTCATCGGATGTTCGCCGATGC
GACCCGGCAGGCGATGGACTACACGGCGATCGAGGGCCCGCGTGAACCCGCCGGCGCGTTCGCGGCCACGGTGCGCGAGT
TCATCGCGGCGGGCGGCAAGGGCATGAACATCACCGCGCCGTTCAAGCTGGCCGCGTTCGAGCTGGCCGACGCGCGCAGC
GAGCGGGCGAGCCTGGCGGGCGCGGCGAACGCATTCAAGTTCGACGGCGGCCGGATTCTGGCCGAGAACTTCGACGGCAT
CGGCCTGCTGCGCGACATCGAGGTGAATCTGCACGCGCCGCTCGCGGGCCGGCGCGTGCTGCTGCTCGGTGCCGGCGGCG
CGGCGCGCGGCGCGCTGCTGCCGTTTCTCGGCGCGGGCCCCGCGGAACTGGTGATTGCCAACCGTCATGTCGAGAAGGCG
CAGGCGCTGGTTTCGCAGGGCGCCGCGCTCGGGCCGGCGCGCGCCTGCGCTTACGCCGAGCTGGAGCGGATGGGGCGCTT
CGAGCTGGTCGTCAACGCGACCTCCGCCAGCCTCACGGGAGATTTGCCGCCGGTGCCGCCCGGCGTCTTCAGCCCGCACG
GCACCGCCTATGAACTGGCCTATGGCAAGCGTCTGACGCCGTTCCTGCGGCTGGCCCGCAATGCCGGCGTCGCCGGTATC
GCGGACGGCGTCGGCATGCTGGTCGAGCAGGCCGCCGAAGCCTTCGCTTGGTGGCGCGGCGTGCGCCCGGACACGCAGGC
GGTGATCGACCAGCTGGCCGTGCCGCTCGATTAG

Upstream 100 bases:

>100_bases
GGCCAGCACAACGCCGAAATCGCGCGAGCGCTGGGTTTCACGGCGGCCGAGATCGAGGCGATGCAGGCCGATGGCGTGCT
GTACGACAAGTGAGGCGACG

Downstream 100 bases:

>100_bases
CGCCGCGCTGCCTCCGGTTCCGGTCCGGGCCACGGTCGCGCCGGAGCCCGGCGCCGCGGCGCAGGCCGTCACGCGCCGGG
CTTCGCCTGGCCGTGCCGGC

Product: Shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRDTYAVIGNPIGHTKSPMIHRMFADATRQAMDYTAIEGPREPAGAFAATVREFIAAGGKGMNITAPFKLAAFELADARS
ERASLAGAANAFKFDGGRILAENFDGIGLLRDIEVNLHAPLAGRRVLLLGAGGAARGALLPFLGAGPAELVIANRHVEKA
QALVSQGAALGPARACAYAELERMGRFELVVNATSASLTGDLPPVPPGVFSPHGTAYELAYGKRLTPFLRLARNAGVAGI
ADGVGMLVEQAAEAFAWWRGVRPDTQAVIDQLAVPLD

Sequences:

>Translated_277_residues
MRDTYAVIGNPIGHTKSPMIHRMFADATRQAMDYTAIEGPREPAGAFAATVREFIAAGGKGMNITAPFKLAAFELADARS
ERASLAGAANAFKFDGGRILAENFDGIGLLRDIEVNLHAPLAGRRVLLLGAGGAARGALLPFLGAGPAELVIANRHVEKA
QALVSQGAALGPARACAYAELERMGRFELVVNATSASLTGDLPPVPPGVFSPHGTAYELAYGKRLTPFLRLARNAGVAGI
ADGVGMLVEQAAEAFAWWRGVRPDTQAVIDQLAVPLD
>Mature_277_residues
MRDTYAVIGNPIGHTKSPMIHRMFADATRQAMDYTAIEGPREPAGAFAATVREFIAAGGKGMNITAPFKLAAFELADARS
ERASLAGAANAFKFDGGRILAENFDGIGLLRDIEVNLHAPLAGRRVLLLGAGGAARGALLPFLGAGPAELVIANRHVEKA
QALVSQGAALGPARACAYAELERMGRFELVVNATSASLTGDLPPVPPGVFSPHGTAYELAYGKRLTPFLRLARNAGVAGI
ADGVGMLVEQAAEAFAWWRGVRPDTQAVIDQLAVPLD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=275, Percent_Identity=45.0909090909091, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1787983, Length=281, Percent_Identity=27.4021352313167, Blast_Score=74, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320332, Length=296, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28996; Mature: 28996

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDTYAVIGNPIGHTKSPMIHRMFADATRQAMDYTAIEGPREPAGAFAATVREFIAAGGK
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
GMNITAPFKLAAFELADARSERASLAGAANAFKFDGGRILAENFDGIGLLRDIEVNLHAP
CCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCEEEEEEEEEEEECC
LAGRRVLLLGAGGAARGALLPFLGAGPAELVIANRHVEKAQALVSQGAALGPARACAYAE
CCCCEEEEEECCCCCCCCHHHHCCCCCHHEEEECCHHHHHHHHHHCCCCCCHHHHHHHHH
LERMGRFELVVNATSASLTGDLPPVPPGVFSPHGTAYELAYGKRLTPFLRLARNAGVAGI
HHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCHH
ADGVGMLVEQAAEAFAWWRGVRPDTQAVIDQLAVPLD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRDTYAVIGNPIGHTKSPMIHRMFADATRQAMDYTAIEGPREPAGAFAATVREFIAAGGK
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
GMNITAPFKLAAFELADARSERASLAGAANAFKFDGGRILAENFDGIGLLRDIEVNLHAP
CCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCEEEEEEEEEEEECC
LAGRRVLLLGAGGAARGALLPFLGAGPAELVIANRHVEKAQALVSQGAALGPARACAYAE
CCCCEEEEEECCCCCCCCHHHHCCCCCHHEEEECCHHHHHHHHHHCCCCCCHHHHHHHHH
LERMGRFELVVNATSASLTGDLPPVPPGVFSPHGTAYELAYGKRLTPFLRLARNAGVAGI
HHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCHH
ADGVGMLVEQAAEAFAWWRGVRPDTQAVIDQLAVPLD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]