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The map label for this gene is trpB [H]

Identifier: 238024259

GI number: 238024259

Start: 1020931

End: 1022124

Strand: Direct

Name: trpB [H]

Synonym: bglu_2g08420

Alternate gene names: 238024259

Gene position: 1020931-1022124 (Clockwise)

Preceding gene: 238024258

Following gene: 238024260

Centisome position: 36.11

GC content: 68.43

Gene sequence:

>1194_bases
ATGTACAACTTTCCTGATGAGCACGGCCATTTCGGCCCCTATGGCGGCGTGTTCGTCGCCGAAACGCTGATCCACGCGCT
CGACGAACTGCGCGGCGCCTACGAGCGTTTTCGCGACGATCCCGAATTCGTCGCCGAATACCAGCGCGAGCTGAAGCACT
TCGTCGGCCGCCCTTCGCCGATCTATCACGCGCAGCGCTGGAGCGAGATGCTCGGCGGCGCGCAGCTCTACCTGAAGCGC
GAGGACCTGAACCACACCGGCGCCCACAAGATCAACAACGTGATCGGCCAGGCGCTGCTCGCGCGCCGGATGGGCAAGCG
GCGCGTGATCGCCGAGACGGGCGCCGGCCAGCACGGCGTGGCCACGGCCACCATCTGCGCGCGCTTCGGCATGGAGTGCG
TGGTCTACATGGGTGCCGAGGACGTGCGCCGTCAGGCGGCCAACGTCTACCGCATGAAGCTGCTCGGCGCGACCGTGGTG
CCGGTGGAGTCGGGTTCGCGCACGCTGAAGGACGCGCTCAACGAGGCGATGCGCGACTGGGTCACCCACATCGAGTCGAC
CTTCTACATCATCGGCACGGTGGCCGGCCCGCACCCCTATCCGATGCTGGTGCGCGACTTCCAGCGCGTGATCGGCGACG
AGTGCAAGGTGCAGATGCCCGAGCTGGCGGGGCGCCAGCCCGACGCGGTGATCGCCTGCGTCGGCGGCGGCTCGAACGCG
ATGGGGATCTTCTATCCGTACATCGACGACACCGACGTGCAGCTGATCGGCGTCGAGGCGGCCGGCGACGGCCTCGACAC
GGGGCGCCACGCGGCCTCGCTGACGGGCGGCAGCCCCGGCGTGCTGCACGGCAACCGCACCTATCTGCTGCAGGATGCCG
ACGGCCAGATCATCGAGACGCATTCGGTCTCGGCGGGCCTCGACTATCCGGGCGTCGGCCCCGAACACGCCTGGCTCAAG
GACAGCGGCCGCGCGCAGTACGTGCCGATCACCGACGAGGAGGCGCTGAAGGCGTTCCACGAGTGCTGCCGGATCGAGGG
CATCATCCCGGCCCTCGAGTCGAGCCATGCGATCGCCTACGGCGCGAAGCTCGCCCCGAGCCTGCCGAAGGACAAGATCC
TGCTCGTCAACCTGTCGGGCCGCGGCGACAAGGACATGCATACCGTCGCCGAGCGCGGCGGCATCACGCTCTGA

Upstream 100 bases:

>100_bases
TGACGGCGTTCGTGAGCGCGGTGCGCGACGCGGACGCCCGGTGAGCCACAAGCCGGCGCGACCCCCCTCCGGGCCGCGCC
GTCCAATCGAGAGTCACGGC

Downstream 100 bases:

>100_bases
CGCCCGGATGCGCGACCTGATCGAAGAGTCCGCCGGCGCTGCGGCGCGCGAGACCGGCGCGGCTCCGGACGCGGCGCGCG
CGCGCGCGCTGCCCGGCGAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MYNFPDEHGHFGPYGGVFVAETLIHALDELRGAYERFRDDPEFVAEYQRELKHFVGRPSPIYHAQRWSEMLGGAQLYLKR
EDLNHTGAHKINNVIGQALLARRMGKRRVIAETGAGQHGVATATICARFGMECVVYMGAEDVRRQAANVYRMKLLGATVV
PVESGSRTLKDALNEAMRDWVTHIESTFYIIGTVAGPHPYPMLVRDFQRVIGDECKVQMPELAGRQPDAVIACVGGGSNA
MGIFYPYIDDTDVQLIGVEAAGDGLDTGRHAASLTGGSPGVLHGNRTYLLQDADGQIIETHSVSAGLDYPGVGPEHAWLK
DSGRAQYVPITDEEALKAFHECCRIEGIIPALESSHAIAYGAKLAPSLPKDKILLVNLSGRGDKDMHTVAERGGITL

Sequences:

>Translated_397_residues
MYNFPDEHGHFGPYGGVFVAETLIHALDELRGAYERFRDDPEFVAEYQRELKHFVGRPSPIYHAQRWSEMLGGAQLYLKR
EDLNHTGAHKINNVIGQALLARRMGKRRVIAETGAGQHGVATATICARFGMECVVYMGAEDVRRQAANVYRMKLLGATVV
PVESGSRTLKDALNEAMRDWVTHIESTFYIIGTVAGPHPYPMLVRDFQRVIGDECKVQMPELAGRQPDAVIACVGGGSNA
MGIFYPYIDDTDVQLIGVEAAGDGLDTGRHAASLTGGSPGVLHGNRTYLLQDADGQIIETHSVSAGLDYPGVGPEHAWLK
DSGRAQYVPITDEEALKAFHECCRIEGIIPALESSHAIAYGAKLAPSLPKDKILLVNLSGRGDKDMHTVAERGGITL
>Mature_397_residues
MYNFPDEHGHFGPYGGVFVAETLIHALDELRGAYERFRDDPEFVAEYQRELKHFVGRPSPIYHAQRWSEMLGGAQLYLKR
EDLNHTGAHKINNVIGQALLARRMGKRRVIAETGAGQHGVATATICARFGMECVVYMGAEDVRRQAANVYRMKLLGATVV
PVESGSRTLKDALNEAMRDWVTHIESTFYIIGTVAGPHPYPMLVRDFQRVIGDECKVQMPELAGRQPDAVIACVGGGSNA
MGIFYPYIDDTDVQLIGVEAAGDGLDTGRHAASLTGGSPGVLHGNRTYLLQDADGQIIETHSVSAGLDYPGVGPEHAWLK
DSGRAQYVPITDEEALKAFHECCRIEGIIPALESSHAIAYGAKLAPSLPKDKILLVNLSGRGDKDMHTVAERGGITL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=56.1679790026247, Blast_Score=436, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=392, Percent_Identity=56.6326530612245, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43291; Mature: 43291

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNFPDEHGHFGPYGGVFVAETLIHALDELRGAYERFRDDPEFVAEYQRELKHFVGRPSP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
IYHAQRWSEMLGGAQLYLKREDLNHTGAHKINNVIGQALLARRMGKRRVIAETGAGQHGV
HHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCH
ATATICARFGMECVVYMGAEDVRRQAANVYRMKLLGATVVPVESGSRTLKDALNEAMRDW
HHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHH
VTHIESTFYIIGTVAGPHPYPMLVRDFQRVIGDECKVQMPELAGRQPDAVIACVGGGSNA
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEECHHHCCCCCCEEEEEECCCCCC
MGIFYPYIDDTDVQLIGVEAAGDGLDTGRHAASLTGGSPGVLHGNRTYLLQDADGQIIET
EEEEEECCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCEEECCEEEEEECCCCCEEEE
HSVSAGLDYPGVGPEHAWLKDSGRAQYVPITDEEALKAFHECCRIEGIIPALESSHAIAY
CCCCCCCCCCCCCCCCCEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHCCCCEEEE
GAKLAPSLPKDKILLVNLSGRGDKDMHTVAERGGITL
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MYNFPDEHGHFGPYGGVFVAETLIHALDELRGAYERFRDDPEFVAEYQRELKHFVGRPSP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
IYHAQRWSEMLGGAQLYLKREDLNHTGAHKINNVIGQALLARRMGKRRVIAETGAGQHGV
HHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCH
ATATICARFGMECVVYMGAEDVRRQAANVYRMKLLGATVVPVESGSRTLKDALNEAMRDW
HHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHH
VTHIESTFYIIGTVAGPHPYPMLVRDFQRVIGDECKVQMPELAGRQPDAVIACVGGGSNA
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEECHHHCCCCCCEEEEEECCCCCC
MGIFYPYIDDTDVQLIGVEAAGDGLDTGRHAASLTGGSPGVLHGNRTYLLQDADGQIIET
EEEEEECCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCEEECCEEEEEECCCCCEEEE
HSVSAGLDYPGVGPEHAWLKDSGRAQYVPITDEEALKAFHECCRIEGIIPALESSHAIAY
CCCCCCCCCCCCCCCCCEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHCCCCEEEE
GAKLAPSLPKDKILLVNLSGRGDKDMHTVAERGGITL
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]