Click here to switch to the map view.

The map label for this gene is trpF [H]

Identifier: 238024258

GI number: 238024258

Start: 1020185

End: 1020874

Strand: Direct

Name: trpF [H]

Synonym: bglu_2g08410

Alternate gene names: 238024258

Gene position: 1020185-1020874 (Clockwise)

Preceding gene: 238024257

Following gene: 238024259

Centisome position: 36.08

GC content: 69.86

Gene sequence:

>690_bases
ATGAGCGATACTCTGACTTCCCCCGGCGCCGCGCCGCGCCTTCGCACCCGCATCAAGCTGTGCGGGCTGTCCCGTCCCGC
CGACGTCGAGCACGCGGTCGCGCTCGGTGTCGACGCGGTCGGTTTCGTGTTCTACCCCAAGAGCCCGCGCGCGGTCACGC
CGCAGCAGGCGGCCGAGCTCGCGCGCCGGCTGCCGCCGTTCGTCTCGGCGGTCGGCCTGTTCGTCAACGCGAGCGCCGAC
GAGCTCGCGCGCGTGCTCGACGCGGTGCCGCTCACCACGCTGCAGTTCCACGGCGACGAGACGCCCGAGCACTGCCTGAC
GCTCGCGCGCGCGGCGCGCCTGCCCTGGCTGCGCGCGTTGCGCGTGGGCGACTCGACGCGGCGCGCCGATTTGGTAGAAT
CGGCACTTCACTATTCGACAGCCGCCGGCTGGTTGTTCGACACACACGTGCCGGACTACGGCGGCAGCGGCAAGGTCTTC
GATTGGTCACTTATTCCCGCAGAGCTCGTGCATCGGGCCGTTTTGAGTGGTGGCTTGAACGCTCGAAACGTCGGTGAGGC
GATTCGCCAGGTCCGCCCCTACGCGGTCGATGTCTCCAGTGGCATCGAGGTAGCGGGCGAGAAGGGCGTGAAGGATCACG
CCCGGATGACGGCGTTCGTGAGCGCGGTGCGCGACGCGGACGCCCGGTGA

Upstream 100 bases:

>100_bases
GGAGCACGGTCTGGGCCGACCTCGACGCGCCGCCGGCCCCGCCAGCGAACCCCTGATGCGGGCGGCCACGCCCGCGCCCC
GAGCCGATCCCTTGTTGACG

Downstream 100 bases:

>100_bases
GCCACAAGCCGGCGCGACCCCCCTCCGGGCCGCGCCGTCCAATCGAGAGTCACGGCATGTACAACTTTCCTGATGAGCAC
GGCCATTTCGGCCCCTATGG

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSDTLTSPGAAPRLRTRIKLCGLSRPADVEHAVALGVDAVGFVFYPKSPRAVTPQQAAELARRLPPFVSAVGLFVNASAD
ELARVLDAVPLTTLQFHGDETPEHCLTLARAARLPWLRALRVGDSTRRADLVESALHYSTAAGWLFDTHVPDYGGSGKVF
DWSLIPAELVHRAVLSGGLNARNVGEAIRQVRPYAVDVSSGIEVAGEKGVKDHARMTAFVSAVRDADAR

Sequences:

>Translated_229_residues
MSDTLTSPGAAPRLRTRIKLCGLSRPADVEHAVALGVDAVGFVFYPKSPRAVTPQQAAELARRLPPFVSAVGLFVNASAD
ELARVLDAVPLTTLQFHGDETPEHCLTLARAARLPWLRALRVGDSTRRADLVESALHYSTAAGWLFDTHVPDYGGSGKVF
DWSLIPAELVHRAVLSGGLNARNVGEAIRQVRPYAVDVSSGIEVAGEKGVKDHARMTAFVSAVRDADAR
>Mature_228_residues
SDTLTSPGAAPRLRTRIKLCGLSRPADVEHAVALGVDAVGFVFYPKSPRAVTPQQAAELARRLPPFVSAVGLFVNASADE
LARVLDAVPLTTLQFHGDETPEHCLTLARAARLPWLRALRVGDSTRRADLVESALHYSTAAGWLFDTHVPDYGGSGKVFD
WSLIPAELVHRAVLSGGLNARNVGEAIRQVRPYAVDVSSGIEVAGEKGVKDHARMTAFVSAVRDADAR

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=204, Percent_Identity=31.8627450980392, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24541; Mature: 24410

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTLTSPGAAPRLRTRIKLCGLSRPADVEHAVALGVDAVGFVFYPKSPRAVTPQQAAEL
CCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHH
ARRLPPFVSAVGLFVNASADELARVLDAVPLTTLQFHGDETPEHCLTLARAARLPWLRAL
HHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCHHHHHH
RVGDSTRRADLVESALHYSTAAGWLFDTHVPDYGGSGKVFDWSLIPAELVHRAVLSGGLN
HCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
ARNVGEAIRQVRPYAVDVSSGIEVAGEKGVKDHARMTAFVSAVRDADAR
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDTLTSPGAAPRLRTRIKLCGLSRPADVEHAVALGVDAVGFVFYPKSPRAVTPQQAAEL
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHH
ARRLPPFVSAVGLFVNASADELARVLDAVPLTTLQFHGDETPEHCLTLARAARLPWLRAL
HHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCHHHHHH
RVGDSTRRADLVESALHYSTAAGWLFDTHVPDYGGSGKVFDWSLIPAELVHRAVLSGGLN
HCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
ARNVGEAIRQVRPYAVDVSSGIEVAGEKGVKDHARMTAFVSAVRDADAR
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA