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The map label for this gene is adh [H]

Identifier: 238024174

GI number: 238024174

Start: 909602

End: 910630

Strand: Reverse

Name: adh [H]

Synonym: bglu_2g07530

Alternate gene names: 238024174

Gene position: 910630-909602 (Counterclockwise)

Preceding gene: 238024175

Following gene: 238024173

Centisome position: 32.21

GC content: 68.12

Gene sequence:

>1029_bases
ATGAAAGCACTCGTTTATCACGGACCAGGCAGCAAGTCGCTTGACGATTGCCCGAAGCCTGAGTTGATCAAGCCCACCGA
TGCGCTGGTGCGCATCACCCGCACCACGATCTGCGGCACCGATCTGCATATCCTCAAGGGCGACGTGCCGAGCTGCGAGC
CCGGCCGCATCCTCGGCCACGAAGGCGTGGGCGTGATCGACGCGGTGGGCACGGCGGTGGAAACGCTCAAGCCCGGCGAC
CACGTACTGATATCGTGCATCACGCGCTGCGGGCGCTGCGACTATTGCCGGCGGGGCATGTATTCGCATTGCAGCACCGG
CGGCTGGATTCTCGGCAACCGGATCGACGGCACCCAGGCCGAGTTCACGCGGATCCCGCACGCCGAGACGAGCCTGATGC
CGATCCCGCCGGGCGTGGACGAGGACGCGCTCGTGATGCTGTCCGACATCCTGCCCACCGGCTATGAATGCGGCGTGCTC
AACGGCAAGGTGCAGCCTGGCAGCACGGTCGCGATCGTCGGCGCCGGCCCGATCGGGCTGGCCGCGCTGCTGACGGCGCA
GTTCTACGCGCCGGCGCGGATCCTGGTGATCGATCCCGACCGCAAGCGGCTCGAGGCGGCGCGCCACTTCGGCGCCACCG
ACTGCATCGCCGACGACGCCGCGCGCACCGTGATGGCGCTGACCGATGGCCTCGGGGTGGACTGCGCGATCGAGGCGGTG
GGCATCCCCGCCACCTTCGAGCTGTGCACCTCCATCGTCGCGCCGGGCGGCGTGGTGGCCAACGTCGGCGTGCACGGCGT
CAAGGTGGACCTGCACCTGGAGCAGCTCTGGGATCGCAACATCTCGATCACGACGCGGCTCGTCGATACCAGCAGCGCGC
CGATGCTGCTCAAGAGCGTGCTCGCCGGCAAGCTCGATCCGGCGCGGCTGATCACGCATCGCTTCCCGCTCGGCGAGATC
GAACGCGCCTACGACGCGTTCGCCCGAGCGCGCGAGACGCAGGCGCTGAAGATCATCATCGAGGCTTAG

Upstream 100 bases:

>100_bases
CGCCGCCCGGCAACGCGCAACCGTGGCGGCGAGGCACTGCGGCCGCGCCTCGCCCGGCGGCCGTGGGTTGCCAGGCAAAG
CGCAGATCGAGGAGTACGCG

Downstream 100 bases:

>100_bases
TAGCCAACGAAGGCGCGGGCGGCACGCGCGCTTTTGCTTTACCATTCACCACACATGAACGGCATCGCCGCGCACGCTCG
CGGTGAAAGCCGTCGCCCGG

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKALVYHGPGSKSLDDCPKPELIKPTDALVRITRTTICGTDLHILKGDVPSCEPGRILGHEGVGVIDAVGTAVETLKPGD
HVLISCITRCGRCDYCRRGMYSHCSTGGWILGNRIDGTQAEFTRIPHAETSLMPIPPGVDEDALVMLSDILPTGYECGVL
NGKVQPGSTVAIVGAGPIGLAALLTAQFYAPARILVIDPDRKRLEAARHFGATDCIADDAARTVMALTDGLGVDCAIEAV
GIPATFELCTSIVAPGGVVANVGVHGVKVDLHLEQLWDRNISITTRLVDTSSAPMLLKSVLAGKLDPARLITHRFPLGEI
ERAYDAFARARETQALKIIIEA

Sequences:

>Translated_342_residues
MKALVYHGPGSKSLDDCPKPELIKPTDALVRITRTTICGTDLHILKGDVPSCEPGRILGHEGVGVIDAVGTAVETLKPGD
HVLISCITRCGRCDYCRRGMYSHCSTGGWILGNRIDGTQAEFTRIPHAETSLMPIPPGVDEDALVMLSDILPTGYECGVL
NGKVQPGSTVAIVGAGPIGLAALLTAQFYAPARILVIDPDRKRLEAARHFGATDCIADDAARTVMALTDGLGVDCAIEAV
GIPATFELCTSIVAPGGVVANVGVHGVKVDLHLEQLWDRNISITTRLVDTSSAPMLLKSVLAGKLDPARLITHRFPLGEI
ERAYDAFARARETQALKIIIEA
>Mature_342_residues
MKALVYHGPGSKSLDDCPKPELIKPTDALVRITRTTICGTDLHILKGDVPSCEPGRILGHEGVGVIDAVGTAVETLKPGD
HVLISCITRCGRCDYCRRGMYSHCSTGGWILGNRIDGTQAEFTRIPHAETSLMPIPPGVDEDALVMLSDILPTGYECGVL
NGKVQPGSTVAIVGAGPIGLAALLTAQFYAPARILVIDPDRKRLEAARHFGATDCIADDAARTVMALTDGLGVDCAIEAV
GIPATFELCTSIVAPGGVVANVGVHGVKVDLHLEQLWDRNISITTRLVDTSSAPMLLKSVLAGKLDPARLITHRFPLGEI
ERAYDAFARARETQALKIIIEA

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=348, Percent_Identity=28.448275862069, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4501929, Length=348, Percent_Identity=28.1609195402299, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI34577061, Length=344, Percent_Identity=27.906976744186, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI71565154, Length=342, Percent_Identity=27.1929824561404, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI262073058, Length=346, Percent_Identity=28.3236994219653, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI71743840, Length=346, Percent_Identity=28.3236994219653, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI156523966, Length=335, Percent_Identity=26.5671641791045, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4501939, Length=335, Percent_Identity=26.5671641791045, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4501933, Length=348, Percent_Identity=27.2988505747126, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI71565152, Length=353, Percent_Identity=24.0793201133144, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1786825, Length=388, Percent_Identity=31.4432989690722, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1786552, Length=347, Percent_Identity=30.2593659942363, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787863, Length=336, Percent_Identity=25.8928571428571, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788073, Length=311, Percent_Identity=27.6527331189711, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790045, Length=339, Percent_Identity=28.3185840707965, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082125, Length=352, Percent_Identity=28.6931818181818, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788075, Length=363, Percent_Identity=28.099173553719, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788407, Length=338, Percent_Identity=27.2189349112426, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI226510992, Length=307, Percent_Identity=27.0358306188925, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790718, Length=322, Percent_Identity=26.7080745341615, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081918, Length=272, Percent_Identity=31.6176470588235, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=350, Percent_Identity=27.1428571428571, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71997431, Length=344, Percent_Identity=27.0348837209302, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562876, Length=348, Percent_Identity=26.1494252873563, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17565904, Length=346, Percent_Identity=28.0346820809249, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562878, Length=348, Percent_Identity=26.1494252873563, Blast_Score=98, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320033, Length=343, Percent_Identity=27.9883381924198, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319258, Length=300, Percent_Identity=25.6666666666667, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319955, Length=357, Percent_Identity=27.4509803921569, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322619, Length=357, Percent_Identity=27.4509803921569, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323099, Length=359, Percent_Identity=24.2339832869081, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319257, Length=299, Percent_Identity=26.7558528428094, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=273, Percent_Identity=29.6703296703297, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323729, Length=272, Percent_Identity=28.6764705882353, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=274, Percent_Identity=28.8321167883212, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=209, Percent_Identity=30.622009569378, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=30.4597701149425, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17737895, Length=348, Percent_Identity=28.1609195402299, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17737897, Length=349, Percent_Identity=31.2320916905444, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI221457811, Length=330, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45551930, Length=330, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45550770, Length=330, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36298; Mature: 36298

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVYHGPGSKSLDDCPKPELIKPTDALVRITRTTICGTDLHILKGDVPSCEPGRILGH
CCEEEEECCCCCCCCCCCCCCCCCCHHHHEEEEHHEECCCCEEEEECCCCCCCCCCEECC
EGVGVIDAVGTAVETLKPGDHVLISCITRCGRCDYCRRGMYSHCSTGGWILGNRIDGTQA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCHHHCCCCCEEEECCCCCCHH
EFTRIPHAETSLMPIPPGVDEDALVMLSDILPTGYECGVLNGKVQPGSTVAIVGAGPIGL
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECEECCCCCCCCEEEEEECCHHHH
AALLTAQFYAPARILVIDPDRKRLEAARHFGATDCIADDAARTVMALTDGLGVDCAIEAV
HHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GIPATFELCTSIVAPGGVVANVGVHGVKVDLHLEQLWDRNISITTRLVDTSSAPMLLKSV
CCCHHHHHHHHHHCCCCEEEECCCEEEEEEEEHHHHHCCCCEEEEEEECCCCCHHHHHHH
LAGKLDPARLITHRFPLGEIERAYDAFARARETQALKIIIEA
HHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MKALVYHGPGSKSLDDCPKPELIKPTDALVRITRTTICGTDLHILKGDVPSCEPGRILGH
CCEEEEECCCCCCCCCCCCCCCCCCHHHHEEEEHHEECCCCEEEEECCCCCCCCCCEECC
EGVGVIDAVGTAVETLKPGDHVLISCITRCGRCDYCRRGMYSHCSTGGWILGNRIDGTQA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCHHHCCCCCEEEECCCCCCHH
EFTRIPHAETSLMPIPPGVDEDALVMLSDILPTGYECGVLNGKVQPGSTVAIVGAGPIGL
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECEECCCCCCCCEEEEEECCHHHH
AALLTAQFYAPARILVIDPDRKRLEAARHFGATDCIADDAARTVMALTDGLGVDCAIEAV
HHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GIPATFELCTSIVAPGGVVANVGVHGVKVDLHLEQLWDRNISITTRLVDTSSAPMLLKSV
CCCHHHHHHHHHHCCCCEEEECCCEEEEEEEEHHHHHCCCCEEEEEEECCCCCHHHHHHH
LAGKLDPARLITHRFPLGEIERAYDAFARARETQALKIIIEA
HHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2846513 [H]