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The map label for this gene is crt [H]

Identifier: 238024069

GI number: 238024069

Start: 756361

End: 757155

Strand: Direct

Name: crt [H]

Synonym: bglu_2g06300

Alternate gene names: 238024069

Gene position: 756361-757155 (Clockwise)

Preceding gene: 238024068

Following gene: 238024070

Centisome position: 26.75

GC content: 74.97

Gene sequence:

>795_bases
ATGATCGAACTGAGCGAACACGACGACGGCGCGATCGCGCTCGTCACCCTGTCCCGGCCGCCCGCCAACGCGTTCCATGC
CGACGGCCTCGCCGCGCTCGAACGCACCGTGGCGCAGCTCGACGCCGCGCCGCGCGTGCGCGCGCTGGTGGTGACCGGCG
CCGGGCCGAAATTCTTCAGCGGCGGTGCCGATCTCGACACCTTCGCGAGCGGCGACCGTGCCGTGGCGCGCGAGATGGCG
GCGCGCTTCGGCGCCGCGTTCGCCAAGCTGCGCGCCGCGCGCTGCGTGACGATCGCCGCGATCAACGGCTATGCGATGGG
CGGCGGGCTCGAATGCGCGCTGGCCTGCGACATGCGGATCGCCGAGCGGCATGCGCAGATGGCGCTGCCCGAGCCGTCGG
TGGGCCTGCTGCCGTGCGGGCTCGGCACCCAGACACTGCCGGCGCTGGTCGGCGAGGGCTGGGCCAAGCGCATCGTGCTG
GCGGGCGAGCGCGTGGACGCCGAGACCGCGCTGCGCATCGGCCTCGTCGAGGAGGTGGTGGACACCGGCGGCGCGCGCGA
GGCGGCGCTCGCGCTGGCGCGCCGCGTGGCCGGGCTCGCGCCGCACGCGGTGGAATCGAGCAAGCGGCTGATCGCGCTCG
CGCGCAACGGCGTGCCGTTCGAGGCGGCGGTGGCGATCGAGCGCGAGCGCTTCGTGGATCTGTTCGAGACCGGCGAGCCG
CGCGAGGGCGTGGCCGCGTTTTTTGGCAAGCGGCGCCCGGACTGGCGCGCCGGCGGCCAGGGAGAGACGCGATGA

Upstream 100 bases:

>100_bases
CGCAGCAGCTCTACCAGGCGCTCAGCAGCCGCGGCGACGGCAAGCTCGATTTCTCGGCGGTGATCCGCCTTTATCAGCAA
CCCGCGAACGAGGAGCCGCG

Downstream 100 bases:

>100_bases
GCACGCTGCCCGAGGCGTCGGGCGACGCCGCCGTGCCGCCGGCCGGCCAGGCCGGCGCGGCCGCCTCGCAAGCCGGGGCG
CCGTCCGGCCCCGAGGTGAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MIELSEHDDGAIALVTLSRPPANAFHADGLAALERTVAQLDAAPRVRALVVTGAGPKFFSGGADLDTFASGDRAVAREMA
ARFGAAFAKLRAARCVTIAAINGYAMGGGLECALACDMRIAERHAQMALPEPSVGLLPCGLGTQTLPALVGEGWAKRIVL
AGERVDAETALRIGLVEEVVDTGGAREAALALARRVAGLAPHAVESSKRLIALARNGVPFEAAVAIERERFVDLFETGEP
REGVAAFFGKRRPDWRAGGQGETR

Sequences:

>Translated_264_residues
MIELSEHDDGAIALVTLSRPPANAFHADGLAALERTVAQLDAAPRVRALVVTGAGPKFFSGGADLDTFASGDRAVAREMA
ARFGAAFAKLRAARCVTIAAINGYAMGGGLECALACDMRIAERHAQMALPEPSVGLLPCGLGTQTLPALVGEGWAKRIVL
AGERVDAETALRIGLVEEVVDTGGAREAALALARRVAGLAPHAVESSKRLIALARNGVPFEAAVAIERERFVDLFETGEP
REGVAAFFGKRRPDWRAGGQGETR
>Mature_264_residues
MIELSEHDDGAIALVTLSRPPANAFHADGLAALERTVAQLDAAPRVRALVVTGAGPKFFSGGADLDTFASGDRAVAREMA
ARFGAAFAKLRAARCVTIAAINGYAMGGGLECALACDMRIAERHAQMALPEPSVGLLPCGLGTQTLPALVGEGWAKRIVL
AGERVDAETALRIGLVEEVVDTGGAREAALALARRVAGLAPHAVESSKRLIALARNGVPFEAAVAIERERFVDLFETGEP
REGVAAFFGKRRPDWRAGGQGETR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=255, Percent_Identity=32.156862745098, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI68989263, Length=276, Percent_Identity=30.7971014492754, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI213417737, Length=234, Percent_Identity=27.3504273504274, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157694516, Length=234, Percent_Identity=27.3504273504274, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI261878539, Length=181, Percent_Identity=32.5966850828729, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI20127408, Length=180, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542718, Length=245, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157694520, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI62530384, Length=211, Percent_Identity=26.0663507109005, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=260, Percent_Identity=36.5384615384615, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI221142681, Length=252, Percent_Identity=33.7301587301587, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788682, Length=189, Percent_Identity=35.978835978836, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790281, Length=198, Percent_Identity=32.3232323232323, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=26.5384615384615, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787660, Length=255, Percent_Identity=30.1960784313725, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=32.6612903225806, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=29.9595141700405, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=28.8135593220339, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=175, Percent_Identity=32.5714285714286, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144276, Length=175, Percent_Identity=33.1428571428571, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508953, Length=175, Percent_Identity=33.1428571428571, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508951, Length=175, Percent_Identity=33.1428571428571, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=220, Percent_Identity=29.5454545454545, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=255, Percent_Identity=24.7058823529412, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=263, Percent_Identity=23.1939163498099, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=29.045643153527, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=29.045643153527, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=29.5019157088123, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583165, Length=204, Percent_Identity=24.5098039215686, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357171, Length=255, Percent_Identity=28.6274509803922, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921018, Length=184, Percent_Identity=25.5434782608696, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650670, Length=191, Percent_Identity=31.9371727748691, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583077, Length=180, Percent_Identity=32.7777777777778, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583079, Length=180, Percent_Identity=32.7777777777778, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19921000, Length=180, Percent_Identity=32.7777777777778, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19922422, Length=263, Percent_Identity=20.9125475285171, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27620; Mature: 27620

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELSEHDDGAIALVTLSRPPANAFHADGLAALERTVAQLDAAPRVRALVVTGAGPKFFS
CCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHCC
GGADLDTFASGDRAVAREMAARFGAAFAKLRAARCVTIAAINGYAMGGGLECALACDMRI
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEECCCCEEEEEHHHHH
AERHAQMALPEPSVGLLPCGLGTQTLPALVGEGWAKRIVLAGERVDAETALRIGLVEEVV
HHHHHHHCCCCCCCCEEECCCCHHHHHHHHCCHHHHEEEEECCCCCHHHHHHHHHHHHHH
DTGGAREAALALARRVAGLAPHAVESSKRLIALARNGVPFEAAVAIERERFVDLFETGEP
HCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCHHHEEHHHHHHHHHHHCCCC
REGVAAFFGKRRPDWRAGGQGETR
HHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIELSEHDDGAIALVTLSRPPANAFHADGLAALERTVAQLDAAPRVRALVVTGAGPKFFS
CCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHCC
GGADLDTFASGDRAVAREMAARFGAAFAKLRAARCVTIAAINGYAMGGGLECALACDMRI
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEECCCCEEEEEHHHHH
AERHAQMALPEPSVGLLPCGLGTQTLPALVGEGWAKRIVLAGERVDAETALRIGLVEEVV
HHHHHHHCCCCCCCCEEECCCCHHHHHHHHCCHHHHEEEEECCCCCHHHHHHHHHHHHHH
DTGGAREAALALARRVAGLAPHAVESSKRLIALARNGVPFEAAVAIERERFVDLFETGEP
HCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCHHHEEHHHHHHHHHHHCCCC
REGVAAFFGKRRPDWRAGGQGETR
HHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]