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The map label for this gene is ygbM [C]

Identifier: 238023937

GI number: 238023937

Start: 582930

End: 583706

Strand: Reverse

Name: ygbM [C]

Synonym: bglu_2g04860

Alternate gene names: 238023937

Gene position: 583706-582930 (Counterclockwise)

Preceding gene: 238023938

Following gene: 238023936

Centisome position: 20.65

GC content: 71.04

Gene sequence:

>777_bases
ATGCCACGCTTTGCCGCCAATCTTTCGATGATGTACCAGGAGCACCCGTTCCTCGAGCGCTTCGCCGCCGCGGCGCGCGA
CGGCTTCCGGGCGGTCGAGTACCTGTTCCCCTATGCGTTCCCGGCCGCCGAGCTGAAGGCGCGGCTCGACGGCGCCGGGC
TCGTGCAGGCGCTGTTCAACGCCCCGCCCGGCGACTGGGCGGCCGGCGAACGCGGCATCGCCGCGCTGCCGGGCCGCGAG
GACGAATTCCGCCGCGCCGTGGAGACCGCGCTCGACTACGCGCGCGTGATCGGCAACGACAAGCTGCACGTGATGGCCGG
CCTGGTGGCGGCCGATGCCGACCGCGCGCGCCACCGCGACGTCTACCTGCGCAATCTCGCCTATGCGGCGCAGGCCGCGC
GGGGCGCCGGGCTGCAGGTGCTGATCGAGCCGATCAACCCGCGCGACATGCCCGGCTACTTCCTGAACCGCCAGGACGAC
GCGCAGGCGATCTGCCGCGAGGTGGGCGCGCCGAACCTGCGCGTGCAGTTCGATTGCTATCACTGCCAGATCGTCGAGGG
CGACCTCGCGAAGAAGCTCGAACGCGACTTCGCCGGCATCGGCCACATCCAGGTGGCAGGCGTGCCCGAGCGGCACGAGC
CGGACCTCGGCGAACTGAATTATCCGTACCTGTTCGCCCTGCTCGACCGGCTCGGCTACGACGGCTGGATCGGCTGCGAA
TACCGGCCGAAGGCCGGCACCTCCGACGGCCTCGGCTGGCTGCGCCCGTACCGGTGA

Upstream 100 bases:

>100_bases
AGCCGATCACGCGCGCCCGGCAGCCCTGATGCGTTTTTTCCGCCGCGCGCCGGGCCAGCCCGTGCGCGGCGCCGCTCCTC
CTTCTGATGGAACCGCCGCC

Downstream 100 bases:

>100_bases
GCCGTCGCGCCCTCGCTTCGCGCCGCGTCGCGCGCCTCTGAACCGACCCACGCACAACGCCCATGAAAGTCCTGATCACC
GGCGGCGCCGGCTTCCTCGG

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPRFAANLSMMYQEHPFLERFAAAARDGFRAVEYLFPYAFPAAELKARLDGAGLVQALFNAPPGDWAAGERGIAALPGRE
DEFRRAVETALDYARVIGNDKLHVMAGLVAADADRARHRDVYLRNLAYAAQAARGAGLQVLIEPINPRDMPGYFLNRQDD
AQAICREVGAPNLRVQFDCYHCQIVEGDLAKKLERDFAGIGHIQVAGVPERHEPDLGELNYPYLFALLDRLGYDGWIGCE
YRPKAGTSDGLGWLRPYR

Sequences:

>Translated_258_residues
MPRFAANLSMMYQEHPFLERFAAAARDGFRAVEYLFPYAFPAAELKARLDGAGLVQALFNAPPGDWAAGERGIAALPGRE
DEFRRAVETALDYARVIGNDKLHVMAGLVAADADRARHRDVYLRNLAYAAQAARGAGLQVLIEPINPRDMPGYFLNRQDD
AQAICREVGAPNLRVQFDCYHCQIVEGDLAKKLERDFAGIGHIQVAGVPERHEPDLGELNYPYLFALLDRLGYDGWIGCE
YRPKAGTSDGLGWLRPYR
>Mature_257_residues
PRFAANLSMMYQEHPFLERFAAAARDGFRAVEYLFPYAFPAAELKARLDGAGLVQALFNAPPGDWAAGERGIAALPGRED
EFRRAVETALDYARVIGNDKLHVMAGLVAADADRARHRDVYLRNLAYAAQAARGAGLQVLIEPINPRDMPGYFLNRQDDA
QAICREVGAPNLRVQFDCYHCQIVEGDLAKKLERDFAGIGHIQVAGVPERHEPDLGELNYPYLFALLDRLGYDGWIGCEY
RPKAGTSDGLGWLRPYR

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=262, Percent_Identity=45.4198473282443, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=44.4444444444444, Blast_Score=178, Evalue=5e-45,
Organism=Escherichia coli, GI1789095, Length=259, Percent_Identity=49.4208494208494, Blast_Score=257, Evalue=5e-70,
Organism=Escherichia coli, GI1786718, Length=258, Percent_Identity=45.7364341085271, Blast_Score=242, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17552022, Length=240, Percent_Identity=38.75, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI17530883, Length=256, Percent_Identity=38.671875, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 28725; Mature: 28594

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSMMYQEHPFLERFAAAARDGFRAVEYLFPYAFPAAELKARLDGAGLVQALFN
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHC
APPGDWAAGERGIAALPGREDEFRRAVETALDYARVIGNDKLHVMAGLVAADADRARHRD
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VYLRNLAYAAQAARGAGLQVLIEPINPRDMPGYFLNRQDDAQAICREVGAPNLRVQFDCY
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEE
HCQIVEGDLAKKLERDFAGIGHIQVAGVPERHEPDLGELNYPYLFALLDRLGYDGWIGCE
EEEEECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCE
YRPKAGTSDGLGWLRPYR
ECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRFAANLSMMYQEHPFLERFAAAARDGFRAVEYLFPYAFPAAELKARLDGAGLVQALFN
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHC
APPGDWAAGERGIAALPGREDEFRRAVETALDYARVIGNDKLHVMAGLVAADADRARHRD
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VYLRNLAYAAQAARGAGLQVLIEPINPRDMPGYFLNRQDDAQAICREVGAPNLRVQFDCY
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEE
HCQIVEGDLAKKLERDFAGIGHIQVAGVPERHEPDLGELNYPYLFALLDRLGYDGWIGCE
EEEEECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCE
YRPKAGTSDGLGWLRPYR
ECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]