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The map label for this gene is tcp [H]

Identifier: 238023909

GI number: 238023909

Start: 545582

End: 547165

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g04510

Alternate gene names: 238023909

Gene position: 547165-545582 (Counterclockwise)

Preceding gene: 238023911

Following gene: 238023908

Centisome position: 19.35

GC content: 64.84

Gene sequence:

>1584_bases
ATGAAAAACATGACCGTAGGCCAGAAGCTCACTGGCGCGTTCGGAATCGTCATACTGATTTCGCTGATCGGCAGCGCGAT
CTCCATCGTCAATTTCCTGCGCCTGAACGACGCCAACGGATGGAACATTCATAGCTATCGCGTGCTGCGAGCGAACGACG
AGATGTTGGCCAACATGGTCAACATGGAGACGGGAGTACGCGGCTACGTGATTTCCGGGGACGACAAATTTCTCGATCCC
TATGTGGCCGGCCAAGGCCAGTTCACCAAATCGTACGAGCTCATCCACGGCCTCACCTCGGACAACGCCGCCCAGCAACA
GCGCCTGGAGGAGCTGCTGCAGCTGCGCAACAAGGTGGGCAGCGTCGCCGAGAAGCTGATCGCGCTGAGGCGCGACGTCA
ACGCGGGAACCCAGCCGCTGAGCGCGCTCACGGATGAATTCAAGCTCGGCAAGGACAAGCAGTTCATGGATCGCTACCGT
GCGGTGTCTGCCGATGTCGGCAATGCCGAACAGGCCCTGCTCGACCAGCGCTCCGGCCAGGTCGCCACGATGACCAACGC
CACCATGTTCACCTTGACGGCCGCCGGCCTGGTCACGATCACCCTCGCGATCGTGTTGGGCATCGTCATTACGCGCGGCA
TCCTGCGGGCGCTGGGCGGCGAGCCCGCCGCGGCCGCGAGCGTGGCCAGCCGCATCGCGCAGGGCGACCTCTCGGTGGCG
GCGCCGGTTCGCGACAAGGATCAGAGCAGCCTGATGGCGTCGCTGGAGGGCATGCGGCAGCAACTGAGGGGCATCGTCGC
GGGCATCCAGTCGTCCGCCGAGTCGATCAAGTCGGCCGCGGGTGAAATCGCCCAAGGCAATCTGGACCTGTCGCAACGCA
CCGAAGAGCAAGCCGCCTCGCTGGAGGAAACCGCCGCGAGCATGGAGCAGTTGACCTCGACCGTCCGGCAGAACACCGAT
AGCGCGAAGCAGGCCAACATGCTCGCCACCAATGCGTGCGACGTGGCGGTGCGCGGCGGTAACGTCGTGGACCAGGTCGT
CGAATCGATGAAGTCGATCTCGGAAAGCTCCGGCAAGGTATCGCAAATCATCACGGTGATCGAGGGCATTGCCTTCCAGA
CCAACATCCTGGCACTCAACGCCGCGGTGGAAGCCGCGCGCGCGGGCGAACAGGGCCGAGGGTTCGCCGTCGTGGCAGGC
GAGGTGCGCACGCTCGCCCAGCGCAGTGCCAGCGCCGCCAAGGAAATCAAGGATCTCATCGAAAGCTCGGTCGATCACGT
GGCAACCGGCGGCGAGCAGGTCAATCGGGCGGGCACCACCATGTCCGAGATCGTCAAGTCGGTGCGCCAGGTGACCGACA
TCATGGGCGAGATCGCCTCGGCATCCGACGAGCAGGGCACGGGCATCGAACAGGTCAACACCGCGGTCAGCCAGATGGAC
GCGGTGACCCAGCAAAACGCGGCGCTGGTGGAACAGGCCTCGGCCGCGGCGCAGGCCATGGCCGAACAGGCCGCCACGCT
TCGCGACGCGGTGGCCTTCTTCCGGATCGGCACGGCCGACGGCAGAGGCGCGGCCTGGCACTAA

Upstream 100 bases:

>100_bases
AGCCGACCATTTTTCCTGCGGCATAGTGCGCGCAAAACTTCAGTAACCAAAACAGTTGCCGACATTACCGATACAGACCA
CCACAATCGGGGAGAAAACC

Downstream 100 bases:

>100_bases
GCCGGCGCCACCGGGTGGCAAAAGCCGCCCGCTGGCGCGACCCGGCGCGGCGGCCCGAGCGGCCGCAGCCAAGCGGCACC
GCGAAGGTCGCCGCGCCCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MKNMTVGQKLTGAFGIVILISLIGSAISIVNFLRLNDANGWNIHSYRVLRANDEMLANMVNMETGVRGYVISGDDKFLDP
YVAGQGQFTKSYELIHGLTSDNAAQQQRLEELLQLRNKVGSVAEKLIALRRDVNAGTQPLSALTDEFKLGKDKQFMDRYR
AVSADVGNAEQALLDQRSGQVATMTNATMFTLTAAGLVTITLAIVLGIVITRGILRALGGEPAAAASVASRIAQGDLSVA
APVRDKDQSSLMASLEGMRQQLRGIVAGIQSSAESIKSAAGEIAQGNLDLSQRTEEQAASLEETAASMEQLTSTVRQNTD
SAKQANMLATNACDVAVRGGNVVDQVVESMKSISESSGKVSQIITVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSASAAKEIKDLIESSVDHVATGGEQVNRAGTTMSEIVKSVRQVTDIMGEIASASDEQGTGIEQVNTAVSQMD
AVTQQNAALVEQASAAAQAMAEQAATLRDAVAFFRIGTADGRGAAWH

Sequences:

>Translated_527_residues
MKNMTVGQKLTGAFGIVILISLIGSAISIVNFLRLNDANGWNIHSYRVLRANDEMLANMVNMETGVRGYVISGDDKFLDP
YVAGQGQFTKSYELIHGLTSDNAAQQQRLEELLQLRNKVGSVAEKLIALRRDVNAGTQPLSALTDEFKLGKDKQFMDRYR
AVSADVGNAEQALLDQRSGQVATMTNATMFTLTAAGLVTITLAIVLGIVITRGILRALGGEPAAAASVASRIAQGDLSVA
APVRDKDQSSLMASLEGMRQQLRGIVAGIQSSAESIKSAAGEIAQGNLDLSQRTEEQAASLEETAASMEQLTSTVRQNTD
SAKQANMLATNACDVAVRGGNVVDQVVESMKSISESSGKVSQIITVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSASAAKEIKDLIESSVDHVATGGEQVNRAGTTMSEIVKSVRQVTDIMGEIASASDEQGTGIEQVNTAVSQMD
AVTQQNAALVEQASAAAQAMAEQAATLRDAVAFFRIGTADGRGAAWH
>Mature_527_residues
MKNMTVGQKLTGAFGIVILISLIGSAISIVNFLRLNDANGWNIHSYRVLRANDEMLANMVNMETGVRGYVISGDDKFLDP
YVAGQGQFTKSYELIHGLTSDNAAQQQRLEELLQLRNKVGSVAEKLIALRRDVNAGTQPLSALTDEFKLGKDKQFMDRYR
AVSADVGNAEQALLDQRSGQVATMTNATMFTLTAAGLVTITLAIVLGIVITRGILRALGGEPAAAASVASRIAQGDLSVA
APVRDKDQSSLMASLEGMRQQLRGIVAGIQSSAESIKSAAGEIAQGNLDLSQRTEEQAASLEETAASMEQLTSTVRQNTD
SAKQANMLATNACDVAVRGGNVVDQVVESMKSISESSGKVSQIITVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSASAAKEIKDLIESSVDHVATGGEQVNRAGTTMSEIVKSVRQVTDIMGEIASASDEQGTGIEQVNTAVSQMD
AVTQQNAALVEQASAAAQAMAEQAATLRDAVAFFRIGTADGRGAAWH

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=326, Percent_Identity=54.601226993865, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI2367378, Length=398, Percent_Identity=50.7537688442211, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1787690, Length=370, Percent_Identity=49.4594594594595, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1788195, Length=267, Percent_Identity=62.1722846441948, Blast_Score=284, Evalue=8e-78,
Organism=Escherichia coli, GI1789453, Length=254, Percent_Identity=40.9448818897638, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55489; Mature: 55489

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMTVGQKLTGAFGIVILISLIGSAISIVNFLRLNDANGWNIHSYRVLRANDEMLANMV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHH
NMETGVRGYVISGDDKFLDPYVAGQGQFTKSYELIHGLTSDNAAQQQRLEELLQLRNKVG
HHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SVAEKLIALRRDVNAGTQPLSALTDEFKLGKDKQFMDRYRAVSADVGNAEQALLDQRSGQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
VATMTNATMFTLTAAGLVTITLAIVLGIVITRGILRALGGEPAAAASVASRIAQGDLSVA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
APVRDKDQSSLMASLEGMRQQLRGIVAGIQSSAESIKSAAGEIAQGNLDLSQRTEEQAAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LEETAASMEQLTSTVRQNTDSAKQANMLATNACDVAVRGGNVVDQVVESMKSISESSGKV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCHH
SQIITVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSASAAKEIKDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ESSVDHVATGGEQVNRAGTTMSEIVKSVRQVTDIMGEIASASDEQGTGIEQVNTAVSQMD
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AVTQQNAALVEQASAAAQAMAEQAATLRDAVAFFRIGTADGRGAAWH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
>Mature Secondary Structure
MKNMTVGQKLTGAFGIVILISLIGSAISIVNFLRLNDANGWNIHSYRVLRANDEMLANMV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHH
NMETGVRGYVISGDDKFLDPYVAGQGQFTKSYELIHGLTSDNAAQQQRLEELLQLRNKVG
HHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SVAEKLIALRRDVNAGTQPLSALTDEFKLGKDKQFMDRYRAVSADVGNAEQALLDQRSGQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
VATMTNATMFTLTAAGLVTITLAIVLGIVITRGILRALGGEPAAAASVASRIAQGDLSVA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
APVRDKDQSSLMASLEGMRQQLRGIVAGIQSSAESIKSAAGEIAQGNLDLSQRTEEQAAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LEETAASMEQLTSTVRQNTDSAKQANMLATNACDVAVRGGNVVDQVVESMKSISESSGKV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCHH
SQIITVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSASAAKEIKDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ESSVDHVATGGEQVNRAGTTMSEIVKSVRQVTDIMGEIASASDEQGTGIEQVNTAVSQMD
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AVTQQNAALVEQASAAAQAMAEQAATLRDAVAFFRIGTADGRGAAWH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]