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The map label for this gene is galM [H]

Identifier: 238023902

GI number: 238023902

Start: 534200

End: 535282

Strand: Reverse

Name: galM [H]

Synonym: bglu_2g04420

Alternate gene names: 238023902

Gene position: 535282-534200 (Counterclockwise)

Preceding gene: 238023903

Following gene: 238023901

Centisome position: 18.93

GC content: 68.14

Gene sequence:

>1083_bases
GTGTCGACCGAAAACCCGAACGCCGCGCAACGCGTGACCGCCAGCGACAGCAGTTCACTGAGCGACGGCAGGACCGTGCA
GACTTTCGTGCTGCGCAATGCGAAGGGCGCCAGCGTGCGAATCAGCGAACTGGGCGGGACGCTCTTGTCGTGGATCGCGC
CCGACCGGCACGGCAACCCGGGGGAGATCCTGCTCGGCCACGATACGCTCGACGATTATCTGAGCTCGCGCGCGTACCTG
GGGGCGCTGGTCGGGCGGTGGGCCAACCGGATCGAGTCGGCGCGCTTCCGGCTGGACGGGGTGGACTACCAGTTGCCCCC
GAACGAAGGCGACAACCTGCTTCACGGCGGGCAAGCCGGTTTTCACCAGCGGCTCTGGCATGCCCGGCCGGCCGGCGACT
CGTTGCTGATGCGGCTCGATTCGCCGGACGGCGAAGGCGGTTTCCCGGGCCAGTTGCAAGTCGAGGTGCGCTACCGGCTG
AGCGACGACGGCACGCTGGAAATCGACTATCTGGCGCAGGCCGACCGGCTGACGCCGGTGAACCTGACCAATCATGCGTA
TTTCAATCTGACGGGGCAGCCGGATCGGGACGTCCGCGACCATCGGCTGACGATCCATGCCGATTCGTATTTCGCGGTCG
ACGGCGCGCTGATTCCGCAGCAACGCGAGCCGGTCGAGCGCAGCCCCTTCGACTTCCGCCGCGCCGCGCCGATCGGCCCG
GGGCTGGACGTCGAGCACGCCCAGATCCGGCTGGCGGGCGGCTTCGACCATTGCTACGTGCTCCACGCCGCCGGCCCCTC
GGCGGGAACGCCCGCCGTGCGCGAAGTGGCGCGTCTCGAGGAGCCGGAAAGCGGACGCGTGCTGACCGTGTCGACGGATC
AGCCCGGCTTGCAGTTCTACAGCGGCAACTTCCTCGAAGGCGTGGCCGCACGCGGCGGAAAGGCGTATCGCCGGCATGCC
GGCTTGTGTCTCGAAACCGGCGGATTCCCGAACCAGATCAACATGGCGGACCGGGACGCGGTACTGGTGATGCCGGGACG
GCCGTATCGCCAGCTCACCCGATACCAGGTCAGTGCCGGCTAG

Upstream 100 bases:

>100_bases
ACCGCTCCGGGGCGGACCGGCGGACCGGCGAATCGACGCCAGCCGCGCAGCGAGCGGCCGGCGCATCGCGAATGAACGTT
CAACCTGAAGGAGACGAGCC

Downstream 100 bases:

>100_bases
CGGATCGCGGCAAGCGCGCGCCCGGCGGCCCGGCCCGCTGTTGCCATGCAAGCTGGCGAAATCGGGCCGTGCCGTGGCGC
GCCCATCCCGTGCCGCGAAA

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSTENPNAAQRVTASDSSSLSDGRTVQTFVLRNAKGASVRISELGGTLLSWIAPDRHGNPGEILLGHDTLDDYLSSRAYL
GALVGRWANRIESARFRLDGVDYQLPPNEGDNLLHGGQAGFHQRLWHARPAGDSLLMRLDSPDGEGGFPGQLQVEVRYRL
SDDGTLEIDYLAQADRLTPVNLTNHAYFNLTGQPDRDVRDHRLTIHADSYFAVDGALIPQQREPVERSPFDFRRAAPIGP
GLDVEHAQIRLAGGFDHCYVLHAAGPSAGTPAVREVARLEEPESGRVLTVSTDQPGLQFYSGNFLEGVAARGGKAYRRHA
GLCLETGGFPNQINMADRDAVLVMPGRPYRQLTRYQVSAG

Sequences:

>Translated_360_residues
MSTENPNAAQRVTASDSSSLSDGRTVQTFVLRNAKGASVRISELGGTLLSWIAPDRHGNPGEILLGHDTLDDYLSSRAYL
GALVGRWANRIESARFRLDGVDYQLPPNEGDNLLHGGQAGFHQRLWHARPAGDSLLMRLDSPDGEGGFPGQLQVEVRYRL
SDDGTLEIDYLAQADRLTPVNLTNHAYFNLTGQPDRDVRDHRLTIHADSYFAVDGALIPQQREPVERSPFDFRRAAPIGP
GLDVEHAQIRLAGGFDHCYVLHAAGPSAGTPAVREVARLEEPESGRVLTVSTDQPGLQFYSGNFLEGVAARGGKAYRRHA
GLCLETGGFPNQINMADRDAVLVMPGRPYRQLTRYQVSAG
>Mature_359_residues
STENPNAAQRVTASDSSSLSDGRTVQTFVLRNAKGASVRISELGGTLLSWIAPDRHGNPGEILLGHDTLDDYLSSRAYLG
ALVGRWANRIESARFRLDGVDYQLPPNEGDNLLHGGQAGFHQRLWHARPAGDSLLMRLDSPDGEGGFPGQLQVEVRYRLS
DDGTLEIDYLAQADRLTPVNLTNHAYFNLTGQPDRDVRDHRLTIHADSYFAVDGALIPQQREPVERSPFDFRRAAPIGPG
LDVEHAQIRLAGGFDHCYVLHAAGPSAGTPAVREVARLEEPESGRVLTVSTDQPGLQFYSGNFLEGVAARGGKAYRRHAG
LCLETGGFPNQINMADRDAVLVMPGRPYRQLTRYQVSAG

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=341, Percent_Identity=41.0557184750733, Blast_Score=245, Evalue=4e-65,
Organism=Escherichia coli, GI1786971, Length=342, Percent_Identity=39.766081871345, Blast_Score=216, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17557428, Length=331, Percent_Identity=29.9093655589124, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI115533334, Length=331, Percent_Identity=29.9093655589124, Blast_Score=138, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319493, Length=374, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6322004, Length=359, Percent_Identity=29.8050139275766, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324399, Length=343, Percent_Identity=28.2798833819242, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24659048, Length=345, Percent_Identity=34.7826086956522, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24583720, Length=347, Percent_Identity=34.0057636887608, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24668278, Length=337, Percent_Identity=32.0474777448071, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24668282, Length=346, Percent_Identity=32.0809248554913, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24641876, Length=350, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR013458
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 39317; Mature: 39186

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS00545 ALDOSE_1_EPIMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTENPNAAQRVTASDSSSLSDGRTVQTFVLRNAKGASVRISELGGTLLSWIAPDRHGNP
CCCCCCCHHHEEECCCCCCCCCCCEEEEEEEECCCCCEEEHHHHCCHHHHHHCCCCCCCC
GEILLGHDTLDDYLSSRAYLGALVGRWANRIESARFRLDGVDYQLPPNEGDNLLHGGQAG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCCCCCCCCEECCCCC
FHQRLWHARPAGDSLLMRLDSPDGEGGFPGQLQVEVRYRLSDDGTLEIDYLAQADRLTPV
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEECCCCEEEEEEECCCCCCCEE
NLTNHAYFNLTGQPDRDVRDHRLTIHADSYFAVDGALIPQQREPVERSPFDFRRAAPIGP
EECCEEEEEECCCCCCCCCCCEEEEEECCEEEECCEECCCCCCCCCCCCCCHHHCCCCCC
GLDVEHAQIRLAGGFDHCYVLHAAGPSAGTPAVREVARLEEPESGRVLTVSTDQPGLQFY
CCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCEEE
SGNFLEGVAARGGKAYRRHAGLCLETGGFPNQINMADRDAVLVMPGRPYRQLTRYQVSAG
CCCHHHHHHHCCCHHHHHHCCEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHEEEECCC
>Mature Secondary Structure 
STENPNAAQRVTASDSSSLSDGRTVQTFVLRNAKGASVRISELGGTLLSWIAPDRHGNP
CCCCCCHHHEEECCCCCCCCCCCEEEEEEEECCCCCEEEHHHHCCHHHHHHCCCCCCCC
GEILLGHDTLDDYLSSRAYLGALVGRWANRIESARFRLDGVDYQLPPNEGDNLLHGGQAG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCCCCCCCCEECCCCC
FHQRLWHARPAGDSLLMRLDSPDGEGGFPGQLQVEVRYRLSDDGTLEIDYLAQADRLTPV
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEECCCCEEEEEEECCCCCCCEE
NLTNHAYFNLTGQPDRDVRDHRLTIHADSYFAVDGALIPQQREPVERSPFDFRRAAPIGP
EECCEEEEEECCCCCCCCCCCEEEEEECCEEEECCEECCCCCCCCCCCCCCHHHCCCCCC
GLDVEHAQIRLAGGFDHCYVLHAAGPSAGTPAVREVARLEEPESGRVLTVSTDQPGLQFY
CCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCEEE
SGNFLEGVAARGGKAYRRHAGLCLETGGFPNQINMADRDAVLVMPGRPYRQLTRYQVSAG
CCCHHHHHHHCCCHHHHHHCCEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7966338; 8905232; 9278503 [H]