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The map label for this gene is aldH [H]

Identifier: 238023833

GI number: 238023833

Start: 440085

End: 441662

Strand: Direct

Name: aldH [H]

Synonym: bglu_2g03710

Alternate gene names: 238023833

Gene position: 440085-441662 (Clockwise)

Preceding gene: 238023820

Following gene: 238023835

Centisome position: 15.57

GC content: 72.88

Gene sequence:

>1578_bases
ATGCAATTGACAGGTGAGATGCTGATCGGCGCCGAAGCGGTGAAGGGCACGGCCGGCACGATGCATGCGTTCGACCCCAC
GCGTGGCGAAACCATTGCCGAGCCGGCGTTCGGCACCGGCAGCGAGGCCGAGGTCGAGCGCGCCTGCGCGCTCGCGCAGC
AGGCGTTCGACGCTTACCGCGCCGAGCCGCTCGAGCGCCGCGCGGCGTTCCTGGAGGCGATCGCCGAGGAGATCCTCGAA
CTCGGCGACGCGCTGATCGAGCGCGCGCAGGCCGAGACGGGCCTGCCCGCCGCGCGCCTGCAGGGCGAGCGCGGCCGTAC
GGTCGGCCAGCTGCGGATGTTCGCGCGGGTGGTGCGCGACGGTTATTTCCTGCGCGCCTCGGTGGACCCGGCGATGCCGG
AGCGCACCCCGCTGCCGCGCGCCGACCTGCGCCTGCAGAAGCTGCCGCTCGGCCCGGTGGCCGTGTTCGGCGCCAGCAAC
TTCCCGCTCGCGTTCTCGGTGGCGGGCGGCGATACCGCTTCGGCGCTGGCGGCCGGCTGCCCGGTGATCGTCAAGGCGCA
CGAAGCCCACCTCGGCACCTCCGAGCTGGTCGGCCGCGCGATCCAGCGCGCCGTGGCGCGCAGCAACATGCCGGCCGGCG
TGTTCTCGCTGCTGATGGGCCCGGGCCGCGTGATCGGCGCCGCGCTCGTCAAGCATCCGGCGATCAAGGCGGTCGGCTTC
ACCGGCTCGCGCCAGGGCGGCCTCGCGCTCGTCAACCTCGCGAACGCGCGCCCCGAGCCGATTCCCGTCTACGCGGAAAT
GAGCAGCATCAACCCGTTCGTGATGTTCCCGGCCGCGCTCGCGGCCCGCGGCGAGAAGATCGCGCAGGGCTTCATCGATT
CGCTGACGATGGGCGTGGGCCAGTTCTGCACCAACCCCGGCCTCGTGATCGCCGTGGACGGCGCCGAGCTCGATGCGTTC
TCGCGGGCCGCGGCCGCCGCGCTCGCCGGCAAGCCGGCCGGCACCATGCTCACGCGCGGCATCGCCGACGCGTATCGCGC
CGGCCGCGCGAAGCTGCAGGAAGCCCCCGGCGTGCGCCAGCTCGGCGCAGGCGGCGCGGGCGAGGGCGGCTGCGCGCTGT
CCGGCGCGCTGTTCGACGTGGACGCGCAGACCTTCCTGCGCGAGCATGCGCTGCGCGACGAGGTGTTCGGCCCGGCCTCG
CTGATCGTGCGCTGCCGCGATTTCGACGAAGTCGCGGCCGTGCTCGAATCGCTCGAAGGCCAGCTCACGGCCACGCTGCA
GATCGACGACGCCGATCTGGCAGCGGCCCGCAAGCTGCTGCCGATCCTCGAACGCAAGGCCGGCCGCCTGCTCGTGAACG
GCTTCCCTACCGGCGTCGAGGTGTGCGACGCGATGGTCCACGGCGGCCCGTTCCCGGCCACCTCGAACGCGATGACCACC
TCGGTCGGCGCGACCGCGATCGAGCGCTTCCTGCGTCCGGTCTGCTACCAGGACTTCCCGGAATCGTTGCTGCCGGAAAG
CCTGCGCGAGTCGAACCCGCTCGGCCTCGCGCGCCTGCGCAACGGCCGGCCCGAGTAA

Upstream 100 bases:

>100_bases
CCGGCCGCATGCCGGGGCGCGTGATTCTTCTAGTCAGTCATCGTATCTGCTGGGCTACAATGCGCGATACGAATCTTTTT
TCGACTGACGGAGCATAGCG

Downstream 100 bases:

>100_bases
GCCGGTCGGGACCGGCGCGGCGACGCTCTCCGAGGCGTGCGCCGTGCCGGTCCGGCTTTTTGGCCGGCTTCGAGGCGGCG
GCGTCGAAGCCGGTGCTTTT

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MQLTGEMLIGAEAVKGTAGTMHAFDPTRGETIAEPAFGTGSEAEVERACALAQQAFDAYRAEPLERRAAFLEAIAEEILE
LGDALIERAQAETGLPAARLQGERGRTVGQLRMFARVVRDGYFLRASVDPAMPERTPLPRADLRLQKLPLGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVIVKAHEAHLGTSELVGRAIQRAVARSNMPAGVFSLLMGPGRVIGAALVKHPAIKAVGF
TGSRQGGLALVNLANARPEPIPVYAEMSSINPFVMFPAALAARGEKIAQGFIDSLTMGVGQFCTNPGLVIAVDGAELDAF
SRAAAAALAGKPAGTMLTRGIADAYRAGRAKLQEAPGVRQLGAGGAGEGGCALSGALFDVDAQTFLREHALRDEVFGPAS
LIVRCRDFDEVAAVLESLEGQLTATLQIDDADLAAARKLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAMTT
SVGATAIERFLRPVCYQDFPESLLPESLRESNPLGLARLRNGRPE

Sequences:

>Translated_525_residues
MQLTGEMLIGAEAVKGTAGTMHAFDPTRGETIAEPAFGTGSEAEVERACALAQQAFDAYRAEPLERRAAFLEAIAEEILE
LGDALIERAQAETGLPAARLQGERGRTVGQLRMFARVVRDGYFLRASVDPAMPERTPLPRADLRLQKLPLGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVIVKAHEAHLGTSELVGRAIQRAVARSNMPAGVFSLLMGPGRVIGAALVKHPAIKAVGF
TGSRQGGLALVNLANARPEPIPVYAEMSSINPFVMFPAALAARGEKIAQGFIDSLTMGVGQFCTNPGLVIAVDGAELDAF
SRAAAAALAGKPAGTMLTRGIADAYRAGRAKLQEAPGVRQLGAGGAGEGGCALSGALFDVDAQTFLREHALRDEVFGPAS
LIVRCRDFDEVAAVLESLEGQLTATLQIDDADLAAARKLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAMTT
SVGATAIERFLRPVCYQDFPESLLPESLRESNPLGLARLRNGRPE
>Mature_525_residues
MQLTGEMLIGAEAVKGTAGTMHAFDPTRGETIAEPAFGTGSEAEVERACALAQQAFDAYRAEPLERRAAFLEAIAEEILE
LGDALIERAQAETGLPAARLQGERGRTVGQLRMFARVVRDGYFLRASVDPAMPERTPLPRADLRLQKLPLGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVIVKAHEAHLGTSELVGRAIQRAVARSNMPAGVFSLLMGPGRVIGAALVKHPAIKAVGF
TGSRQGGLALVNLANARPEPIPVYAEMSSINPFVMFPAALAARGEKIAQGFIDSLTMGVGQFCTNPGLVIAVDGAELDAF
SRAAAAALAGKPAGTMLTRGIADAYRAGRAKLQEAPGVRQLGAGGAGEGGCALSGALFDVDAQTFLREHALRDEVFGPAS
LIVRCRDFDEVAAVLESLEGQLTATLQIDDADLAAARKLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAMTT
SVGATAIERFLRPVCYQDFPESLLPESLRESNPLGLARLRNGRPE

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=361, Percent_Identity=24.9307479224377, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI12007648, Length=421, Percent_Identity=23.0403800475059, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI25952152, Length=267, Percent_Identity=26.2172284644195, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87081896, Length=453, Percent_Identity=27.5938189845475, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788042, Length=324, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789015, Length=441, Percent_Identity=26.0770975056689, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786504, Length=473, Percent_Identity=26.4270613107822, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=429, Percent_Identity=26.3403263403263, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324950, Length=453, Percent_Identity=22.9580573951435, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323822, Length=430, Percent_Identity=25.8139534883721, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319478, Length=277, Percent_Identity=24.9097472924188, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=476, Percent_Identity=24.3697478991597, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362580, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472918, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472926, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472936, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356737, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54867; Mature: 54867

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTGEMLIGAEAVKGTAGTMHAFDPTRGETIAEPAFGTGSEAEVERACALAQQAFDAYR
CCCCCCHHCCHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AEPLERRAAFLEAIAEEILELGDALIERAQAETGLPAARLQGERGRTVGQLRMFARVVRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHC
GYFLRASVDPAMPERTPLPRADLRLQKLPLGPVAVFGASNFPLAFSVAGGDTASALAAGC
CEEEEEECCCCCCCCCCCCHHCCEEECCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCC
PVIVKAHEAHLGTSELVGRAIQRAVARSNMPAGVFSLLMGPGRVIGAALVKHPAIKAVGF
CEEEEECHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEECC
TGSRQGGLALVNLANARPEPIPVYAEMSSINPFVMFPAALAARGEKIAQGFIDSLTMGVG
CCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
QFCTNPGLVIAVDGAELDAFSRAAAAALAGKPAGTMLTRGIADAYRAGRAKLQEAPGVRQ
HHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
LGAGGAGEGGCALSGALFDVDAQTFLREHALRDEVFGPASLIVRCRDFDEVAAVLESLEG
HCCCCCCCCCCEECCCEEECCHHHHHHHHHHHHHCCCCHHHHEEECCHHHHHHHHHHCCC
QLTATLQIDDADLAAARKLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAMTT
CEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHH
SVGATAIERFLRPVCYQDFPESLLPESLRESNPLGLARLRNGRPE
HHHHHHHHHHHHHHHHHCCCHHHCHHHHHCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MQLTGEMLIGAEAVKGTAGTMHAFDPTRGETIAEPAFGTGSEAEVERACALAQQAFDAYR
CCCCCCHHCCHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AEPLERRAAFLEAIAEEILELGDALIERAQAETGLPAARLQGERGRTVGQLRMFARVVRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHC
GYFLRASVDPAMPERTPLPRADLRLQKLPLGPVAVFGASNFPLAFSVAGGDTASALAAGC
CEEEEEECCCCCCCCCCCCHHCCEEECCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCC
PVIVKAHEAHLGTSELVGRAIQRAVARSNMPAGVFSLLMGPGRVIGAALVKHPAIKAVGF
CEEEEECHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEECC
TGSRQGGLALVNLANARPEPIPVYAEMSSINPFVMFPAALAARGEKIAQGFIDSLTMGVG
CCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
QFCTNPGLVIAVDGAELDAFSRAAAAALAGKPAGTMLTRGIADAYRAGRAKLQEAPGVRQ
HHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
LGAGGAGEGGCALSGALFDVDAQTFLREHALRDEVFGPASLIVRCRDFDEVAAVLESLEG
HCCCCCCCCCCEECCCEEECCHHHHHHHHHHHHHCCCCHHHHEEECCHHHHHHHHHHCCC
QLTATLQIDDADLAAARKLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAMTT
CEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHH
SVGATAIERFLRPVCYQDFPESLLPESLRESNPLGLARLRNGRPE
HHHHHHHHHHHHHHHHHCCCHHHCHHHHHCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]