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The map label for this gene is pcaR [H]

Identifier: 238023798

GI number: 238023798

Start: 394002

End: 394790

Strand: Reverse

Name: pcaR [H]

Synonym: bglu_2g03340

Alternate gene names: 238023798

Gene position: 394790-394002 (Counterclockwise)

Preceding gene: 238023801

Following gene: 238023797

Centisome position: 13.96

GC content: 69.71

Gene sequence:

>789_bases
ATGAGCACCGACGACCTGCCGGCCAAGCCCGGCGATTCCTATGTCCAGTCGTTCGCGCGCGGCCTCGCCGTGATCCGAGC
GTTCGACGCCGAGCGCCCCGAGCAGACGCTGACCGAGGTCGCCGCCGCCACCGGCCTCACGCGCGCCGGGGCGCGGCGCA
TCCTGCTGACGCTGCAGACGCTCGGTTACGTGGAGGCCGAAGGACGGCTGTTCCGGCTCACGCCGAAGATCCTCGACCTC
GGCTTCGCGTACCTGACCTCGATGCCGTTCTGGAACCTCGCCGAGCCGGTGATGGAGCAGCTTTCCGCGCGCATACACGA
AAGCTGTTCGGCGGCCGTGCTCGACCGCACCGAGATCGTCTACGTGCTGCGCGTGCCGACCCACAAGATCATGACCATCA
ACCTGTCGATCGGCAGCCGGCTGCCCGCCTACTGCACGTCGATGGGGCGCGTGCTGCTGTCCTCGCTCGACGATGCCGCG
CTCGACGCGCTGCTCGCGCAGAGCCCGATCGCGGCGCACACGCCGCGCACGCTGACCGATCCGGCCGCGCTGAAGGCCGA
GATCGCGGCCGTGCGGCGGCAGGGCTGGGCGATCGTCGACCAGGAGCTCGAGGGCGGGCTGATCTCGCTGTCGGCGCCGA
TCCGCAACCGCCGCGGCAAGGTGATCGCGGCGATGAACATCAGCGGCAACGCACAGCGGCACACCGCCGAGCAGATGGTA
AAGGAATTCCTCGAGCCGCTGCTGGAAGCCTCGCAGATGGTGTCGGCACTGGTGGCGCGGCGCGGCTAG

Upstream 100 bases:

>100_bases
GGCATGTCAAGCTTGCGGGCGGCGCCGTGCGTGCCGCCTCGGTTGGCGCGACCCGACCCCATGCGCTACTCTCTACCGTT
GCACTACCTTGCCCCGACTC

Downstream 100 bases:

>100_bases
GGCGCCCCCGGCCGCGCGTTTCGGCGGGGCGTCGGCCGCGTTCGGCACGCCCGGCCGCCCGCCGTCCGTTTCGCTGGCCC
GCCTTCCCTTGCGCCGCTGG

Product: IclR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSTDDLPAKPGDSYVQSFARGLAVIRAFDAERPEQTLTEVAAATGLTRAGARRILLTLQTLGYVEAEGRLFRLTPKILDL
GFAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDDAA
LDALLAQSPIAAHTPRTLTDPAALKAEIAAVRRQGWAIVDQELEGGLISLSAPIRNRRGKVIAAMNISGNAQRHTAEQMV
KEFLEPLLEASQMVSALVARRG

Sequences:

>Translated_262_residues
MSTDDLPAKPGDSYVQSFARGLAVIRAFDAERPEQTLTEVAAATGLTRAGARRILLTLQTLGYVEAEGRLFRLTPKILDL
GFAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDDAA
LDALLAQSPIAAHTPRTLTDPAALKAEIAAVRRQGWAIVDQELEGGLISLSAPIRNRRGKVIAAMNISGNAQRHTAEQMV
KEFLEPLLEASQMVSALVARRG
>Mature_261_residues
STDDLPAKPGDSYVQSFARGLAVIRAFDAERPEQTLTEVAAATGLTRAGARRILLTLQTLGYVEAEGRLFRLTPKILDLG
FAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDDAAL
DALLAQSPIAAHTPRTLTDPAALKAEIAAVRRQGWAIVDQELEGGLISLSAPIRNRRGKVIAAMNISGNAQRHTAEQMVK
EFLEPLLEASQMVSALVARRG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=258, Percent_Identity=31.3953488372093, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786468, Length=217, Percent_Identity=31.7972350230415, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082359, Length=250, Percent_Identity=28.8, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=24.0174672489083, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789999, Length=246, Percent_Identity=27.2357723577236, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790752, Length=200, Percent_Identity=23.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788581, Length=159, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28448; Mature: 28317

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDDLPAKPGDSYVQSFARGLAVIRAFDAERPEQTLTEVAAATGLTRAGARRILLTLQT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LGYVEAEGRLFRLTPKILDLGFAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIV
HCEEECCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
YVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDDAALDALLAQSPIAAHTPRTLTD
EEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCC
PAALKAEIAAVRRQGWAIVDQELEGGLISLSAPIRNRRGKVIAAMNISGNAQRHTAEQMV
HHHHHHHHHHHHHCCCEEEEHHCCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHH
KEFLEPLLEASQMVSALVARRG
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STDDLPAKPGDSYVQSFARGLAVIRAFDAERPEQTLTEVAAATGLTRAGARRILLTLQT
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LGYVEAEGRLFRLTPKILDLGFAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIV
HCEEECCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
YVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDDAALDALLAQSPIAAHTPRTLTD
EEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCC
PAALKAEIAAVRRQGWAIVDQELEGGLISLSAPIRNRRGKVIAAMNISGNAQRHTAEQMV
HHHHHHHHHHHHHCCCEEEEHHCCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHH
KEFLEPLLEASQMVSALVARRG
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]