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The map label for this gene is ilvE [H]

Identifier: 238023791

GI number: 238023791

Start: 387684

End: 388784

Strand: Direct

Name: ilvE [H]

Synonym: bglu_2g03260

Alternate gene names: 238023791

Gene position: 387684-388784 (Clockwise)

Preceding gene: 238023790

Following gene: 238023799

Centisome position: 13.71

GC content: 68.94

Gene sequence:

>1101_bases
ATGAGCACCGGCAGCACCCCGACTTTCCCGATCGAGCGTCACCCGAATCCGACTTCCGCCGAGGCACGCGCGCGATTGCT
CGAGAATCCCGGCTTCGGCAAGATTTTCACCGACTACATGGTGACGATCCGCTACACGGAAGGCCAGGGCTGGCACGACG
CGAAGATCGAGCCGCGCCGCGCGCTCGAGCTCGATCCGGCAACGCTGGTGCTGCACTATGCGCAGGAAATCTTCGAGGGC
ATGAAGGCGTATCCGCTGCCCGGCGGCAAGGTTGCCCTGTTCCGGCCCGAACAGAACGCGCGCCGGTTCCGCAACTCGGC
GGCGCGCCTCGCGATGGCGCAACTGCCGGAGGAACTGTTCGTGGAAGCCGTGCGCCAGCTCGTGACGCTGGAGCGCGACT
GGATTCCGTCGGCGGAAGGCAGCGCGCTGTATCTGCGCCCGTTCATGATCGCCGACGAGGTGGTGCTCGGCGTGAAGCCG
TCGGCGCAGTACCTGTTCTGCGTGGTGGCGACGCCGGTGGGCGCCTACTTCAAGGGCGACGCGTCGAAAGGCGTGGCGAT
CTGGGTGTCGGACAGCTACACGCGTGCGGCGCCCGGCGGCACCGGCGACGCGAAGTGCGGCGGCAACTACGCGGCGAGCC
TCGCCGCTCAGGCCGAGGCGACGCGCGAGGGCTGCGATCAGGTGGTGTTCCTCGACGCCGTCGAGCGGCGCTGGATCGAG
GAGCTGGGCGGCATGAACGTGTTCTTCGTGTTCGACGACGGCTCGCTGCAGACGCCGCCCCTCACCGGCACGATCCTGCC
CGGCATCACGCGGGCCTCGCTGATCGAACTGGCGCGCGATCTCGGCTACACCGTGCGCGAGGAGCCTTACTCGATCGAGC
AGTGGGAAGCCGACGCAAAGAGCGGGCGGCTGGTGGAGGCGTTCGCCTGCGGCACCGCGGCCGTCGTCACGGCGATCGGG
CAGGTGAAGGGCCGCAAGCACAGCTTCGTGATCGGCGACGGCGGCGCCGGCCCGGTGGCGACGCGGCTCAAGAAGACGCT
GGTGGGCATCCAGACCGGGCGCGAGGCCGATACGCACGGCTGGGTCGACATCCTCGGCTGA

Upstream 100 bases:

>100_bases
GGAGATTTCCGGATGCGCGGAACGCTCAGGTCGATTACAGTGTCCGGTCAGCGCGGCGGCGGGACGTTCCCGCCGCCTCA
ATAAAACAGGAGCGGACCAC

Downstream 100 bases:

>100_bases
AGAAGCGCACGATGTGAGAATCAGCTGGAGCGCCATCGCGAGGAAGGTCGAGCGCGGCCAGCGGTTGCGCGTGCGGCTTG
CGCGATGGCCTGCCGTCGCG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSTGSTPTFPIERHPNPTSAEARARLLENPGFGKIFTDYMVTIRYTEGQGWHDAKIEPRRALELDPATLVLHYAQEIFEG
MKAYPLPGGKVALFRPEQNARRFRNSAARLAMAQLPEELFVEAVRQLVTLERDWIPSAEGSALYLRPFMIADEVVLGVKP
SAQYLFCVVATPVGAYFKGDASKGVAIWVSDSYTRAAPGGTGDAKCGGNYAASLAAQAEATREGCDQVVFLDAVERRWIE
ELGGMNVFFVFDDGSLQTPPLTGTILPGITRASLIELARDLGYTVREEPYSIEQWEADAKSGRLVEAFACGTAAVVTAIG
QVKGRKHSFVIGDGGAGPVATRLKKTLVGIQTGREADTHGWVDILG

Sequences:

>Translated_366_residues
MSTGSTPTFPIERHPNPTSAEARARLLENPGFGKIFTDYMVTIRYTEGQGWHDAKIEPRRALELDPATLVLHYAQEIFEG
MKAYPLPGGKVALFRPEQNARRFRNSAARLAMAQLPEELFVEAVRQLVTLERDWIPSAEGSALYLRPFMIADEVVLGVKP
SAQYLFCVVATPVGAYFKGDASKGVAIWVSDSYTRAAPGGTGDAKCGGNYAASLAAQAEATREGCDQVVFLDAVERRWIE
ELGGMNVFFVFDDGSLQTPPLTGTILPGITRASLIELARDLGYTVREEPYSIEQWEADAKSGRLVEAFACGTAAVVTAIG
QVKGRKHSFVIGDGGAGPVATRLKKTLVGIQTGREADTHGWVDILG
>Mature_365_residues
STGSTPTFPIERHPNPTSAEARARLLENPGFGKIFTDYMVTIRYTEGQGWHDAKIEPRRALELDPATLVLHYAQEIFEGM
KAYPLPGGKVALFRPEQNARRFRNSAARLAMAQLPEELFVEAVRQLVTLERDWIPSAEGSALYLRPFMIADEVVLGVKPS
AQYLFCVVATPVGAYFKGDASKGVAIWVSDSYTRAAPGGTGDAKCGGNYAASLAAQAEATREGCDQVVFLDAVERRWIEE
LGGMNVFFVFDDGSLQTPPLTGTILPGITRASLIELARDLGYTVREEPYSIEQWEADAKSGRLVEAFACGTAAVVTAIGQ
VKGRKHSFVIGDGGAGPVATRLKKTLVGIQTGREADTHGWVDILG

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010904, Length=356, Percent_Identity=37.6404494382022, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI38176287, Length=356, Percent_Identity=37.6404494382022, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI296010906, Length=356, Percent_Identity=37.6404494382022, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI50658084, Length=337, Percent_Identity=37.0919881305638, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI296010902, Length=356, Percent_Identity=33.7078651685393, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI296010900, Length=356, Percent_Identity=33.9887640449438, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI258614015, Length=293, Percent_Identity=36.518771331058, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI48994963, Length=320, Percent_Identity=36.875, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17568601, Length=297, Percent_Identity=38.7205387205387, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17565728, Length=337, Percent_Identity=35.6083086053413, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6322002, Length=356, Percent_Identity=37.6404494382022, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6322608, Length=346, Percent_Identity=37.2832369942197, Blast_Score=220, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24641779, Length=345, Percent_Identity=37.9710144927536, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 39669; Mature: 39538

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGSTPTFPIERHPNPTSAEARARLLENPGFGKIFTDYMVTIRYTEGQGWHDAKIEPRR
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCC
ALELDPATLVLHYAQEIFEGMKAYPLPGGKVALFRPEQNARRFRNSAARLAMAQLPEELF
CEECCHHHHHHHHHHHHHHCHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHH
VEAVRQLVTLERDWIPSAEGSALYLRPFMIADEVVLGVKPSAQYLFCVVATPVGAYFKGD
HHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCEEEECCCCCCEEEEEEECCCCCEEECC
ASKGVAIWVSDSYTRAAPGGTGDAKCGGNYAASLAAQAEATREGCDQVVFLDAVERRWIE
CCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
ELGGMNVFFVFDDGSLQTPPLTGTILPGITRASLIELARDLGYTVREEPYSIEQWEADAK
HHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
SGRLVEAFACGTAAVVTAIGQVKGRKHSFVIGDGGAGPVATRLKKTLVGIQTGREADTHG
CCCEEEEHHCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC
WVDILG
CEEECC
>Mature Secondary Structure 
STGSTPTFPIERHPNPTSAEARARLLENPGFGKIFTDYMVTIRYTEGQGWHDAKIEPRR
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCC
ALELDPATLVLHYAQEIFEGMKAYPLPGGKVALFRPEQNARRFRNSAARLAMAQLPEELF
CEECCHHHHHHHHHHHHHHCHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHH
VEAVRQLVTLERDWIPSAEGSALYLRPFMIADEVVLGVKPSAQYLFCVVATPVGAYFKGD
HHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCEEEECCCCCCEEEEEEECCCCCEEECC
ASKGVAIWVSDSYTRAAPGGTGDAKCGGNYAASLAAQAEATREGCDQVVFLDAVERRWIE
CCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
ELGGMNVFFVFDDGSLQTPPLTGTILPGITRASLIELARDLGYTVREEPYSIEQWEADAK
HHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
SGRLVEAFACGTAAVVTAIGQVKGRKHSFVIGDGGAGPVATRLKKTLVGIQTGREADTHG
CCCEEEEHHCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC
WVDILG
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]