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The map label for this gene is bioH [H]

Identifier: 238023759

GI number: 238023759

Start: 338845

End: 339537

Strand: Reverse

Name: bioH [H]

Synonym: bglu_2g02910

Alternate gene names: 238023759

Gene position: 339537-338845 (Counterclockwise)

Preceding gene: 238023760

Following gene: 238023758

Centisome position: 12.01

GC content: 73.74

Gene sequence:

>693_bases
GTGACCCCGATCGTCCTGATCCCCGGCCTGCTCTGCACGGCCGAAGTCTTCGCCCCCCAGCTTCCCGTGCTCTGGCCGCA
CGGCCCGGTCACGATCGCCTCGACGCTCGGCGGCGACACCATCGGGGAGCTGGCCGCCGCGCTCCTCGCCGACGCGCCGC
CGCGTTTCGCGCTCGCCGGCTACTCGATGGGCGGCTACATCGCGCAGGAGATCCTGCGCCAGGCGCCCGCGCGCGTGACG
CGGCTCGCGCTGCTGAGCACCTCGGCCCGTGCGGACCTGCCGATCCAGATCGAGATGCGCCGCGCGCTAGTCGATGCGGC
CTGCCACGGCGATTTCGACACCGTGCTCGCGAGCCTGTCGATGACCAACGCGCATCCGTCGCGCCGCCGCGACCCGGTGC
TGGCCGCCACCAAGCGGCGCATGGCCGCCGCGATCGGCCGCGCCGGCCTGGCGCGCCAGAGCGAGGCCTTGATCAGCCGC
GTCGATTCGCGCGCGGACCTCGCGGCGATCGCCGTTCCCACGCTCGTGCTGACGGGCGACAGCGATGCCATCGCGCCGCC
CGCCCACGCGCGCGAGATGGCCGACGCGATTCCCGGCGCCAAGCTCGTGATCGTGCCCGAGTGCGGCCACAACGCGACGC
TCGAATGCCCCGAGGCCGTCAATGCCGCGCTGCTTGCGTGGCTCACGGCCTGA

Upstream 100 bases:

>100_bases
GCAGCGGCGCGTCGTGCGTCGGCCGGATGCGGGCGCCGCCCCGGCCGCGCGATAATCGCGTCTGCCCTCGTCAGCCCCCT
TTCGCTCCCGGAGTTCCCGC

Downstream 100 bases:

>100_bases
TCCGTCAGGCCGCGACATGTCCGGCGTCTTGCCCGCGGCGCGGCGCCGAGATCGCAGGGGCGCGAGGCGCGGTGCCGGCG
CATCACGGCCGCGCCGGCCC

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTPIVLIPGLLCTAEVFAPQLPVLWPHGPVTIASTLGGDTIGELAAALLADAPPRFALAGYSMGGYIAQEILRQAPARVT
RLALLSTSARADLPIQIEMRRALVDAACHGDFDTVLASLSMTNAHPSRRRDPVLAATKRRMAAAIGRAGLARQSEALISR
VDSRADLAAIAVPTLVLTGDSDAIAPPAHAREMADAIPGAKLVIVPECGHNATLECPEAVNAALLAWLTA

Sequences:

>Translated_230_residues
MTPIVLIPGLLCTAEVFAPQLPVLWPHGPVTIASTLGGDTIGELAAALLADAPPRFALAGYSMGGYIAQEILRQAPARVT
RLALLSTSARADLPIQIEMRRALVDAACHGDFDTVLASLSMTNAHPSRRRDPVLAATKRRMAAAIGRAGLARQSEALISR
VDSRADLAAIAVPTLVLTGDSDAIAPPAHAREMADAIPGAKLVIVPECGHNATLECPEAVNAALLAWLTA
>Mature_229_residues
TPIVLIPGLLCTAEVFAPQLPVLWPHGPVTIASTLGGDTIGELAAALLADAPPRFALAGYSMGGYIAQEILRQAPARVTR
LALLSTSARADLPIQIEMRRALVDAACHGDFDTVLASLSMTNAHPSRRRDPVLAATKRRMAAAIGRAGLARQSEALISRV
DSRADLAAIAVPTLVLTGDSDAIAPPAHAREMADAIPGAKLVIVPECGHNATLECPEAVNAALLAWLTA

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 23925; Mature: 23794

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIVLIPGLLCTAEVFAPQLPVLWPHGPVTIASTLGGDTIGELAAALLADAPPRFALAG
CCCEEEECHHHHHHHHHCCCCCEECCCCCEEEEHHCCCCHHHHHHHHHHHCCCCCEEEEC
YSMGGYIAQEILRQAPARVTRLALLSTSARADLPIQIEMRRALVDAACHGDFDTVLASLS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHH
MTNAHPSRRRDPVLAATKRRMAAAIGRAGLARQSEALISRVDSRADLAAIAVPTLVLTGD
HCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHEECCEEEEECC
SDAIAPPAHAREMADAIPGAKLVIVPECGHNATLECPEAVNAALLAWLTA
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPIVLIPGLLCTAEVFAPQLPVLWPHGPVTIASTLGGDTIGELAAALLADAPPRFALAG
CCEEEECHHHHHHHHHCCCCCEECCCCCEEEEHHCCCCHHHHHHHHHHHCCCCCEEEEC
YSMGGYIAQEILRQAPARVTRLALLSTSARADLPIQIEMRRALVDAACHGDFDTVLASLS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHH
MTNAHPSRRRDPVLAATKRRMAAAIGRAGLARQSEALISRVDSRADLAAIAVPTLVLTGD
HCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHEECCEEEEECC
SDAIAPPAHAREMADAIPGAKLVIVPECGHNATLECPEAVNAALLAWLTA
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]