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The map label for this gene is gntR [H]

Identifier: 238023753

GI number: 238023753

Start: 331776

End: 332453

Strand: Reverse

Name: gntR [H]

Synonym: bglu_2g02850

Alternate gene names: 238023753

Gene position: 332453-331776 (Counterclockwise)

Preceding gene: 238023754

Following gene: 238023751

Centisome position: 11.76

GC content: 67.85

Gene sequence:

>678_bases
ATGCAAAGCAAGCGGCCCGGACTGGGGCATATGACACGGGCGGAGGCGGCGGCTGAGGAACTGAGGCGCAGGATTCTCGC
CGGAGAGATCGCCGAAGGCACGCCGCTCAAGCAGGACGCGCTCGCCGCCGAGTTCGGCATCAGCCGCATCCCGCTGCGCG
AGGCGCTCGTCCAGCTCGAAAGCGAAGGCCTCGTCAGGATCCTGCCGCACAAGGGCGCGATCGTCGCGGAGTTCTCGATC
GACGAGATCACCGAGCTGTTCGAGCTGCGCGCGCTGCTCGAACCCATGCTGCTGCGCAAGTCGGTGCCCCATCTGGACGC
CGATGATTTCGCCGCGATCCAGCAGGTGCTCGATGCGTTCAGCGACGAGTTGCACGCCAACGCGCCGGCGCACTGGGGCG
AGCTGAACACGCAGCTGCACCAGTTGCTGCTGGCGCGCGCGAACCAGCCCAGGACGGCCGGCATCGTTCATTCGCTGCTG
CAGCAAACCGATCGCCACACGCGCGTGCAGCTGTCGCTGACCGCGCAAAGCGCGGACCGCGCCGAACGCGAGCATGCCGA
GCTGGTCGAGCGATGCAGGCAGCGCGATGCGGAGGGCGCGGCGGCCTTGCTGAAGGCGCACATCGAGCATGTCGGCGACG
AACTGAAGCGTTTCCTCGAAGCACGGCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GATCGCGGCGGGGCCTGCGGCCGCCTGCGCTACCATCGTGGAAAATATGCGGGCCCCCACCCGGGCGCCCGTATCGTGAC
CGACCTTCGATGAATCGACA

Downstream 100 bases:

>100_bases
CCGGCGCAGGCCGGCGCGCGAGGCATGCCGCGCCTCGCCACCCGCGCGGCCTCACCTTCGGGCCGCGCCGCTCCGCCTCT
CCCAGCTCACCTCCAGCGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MQSKRPGLGHMTRAEAAAEELRRRILAGEIAEGTPLKQDALAAEFGISRIPLREALVQLESEGLVRILPHKGAIVAEFSI
DEITELFELRALLEPMLLRKSVPHLDADDFAAIQQVLDAFSDELHANAPAHWGELNTQLHQLLLARANQPRTAGIVHSLL
QQTDRHTRVQLSLTAQSADRAEREHAELVERCRQRDAEGAAALLKAHIEHVGDELKRFLEARRGA

Sequences:

>Translated_225_residues
MQSKRPGLGHMTRAEAAAEELRRRILAGEIAEGTPLKQDALAAEFGISRIPLREALVQLESEGLVRILPHKGAIVAEFSI
DEITELFELRALLEPMLLRKSVPHLDADDFAAIQQVLDAFSDELHANAPAHWGELNTQLHQLLLARANQPRTAGIVHSLL
QQTDRHTRVQLSLTAQSADRAEREHAELVERCRQRDAEGAAALLKAHIEHVGDELKRFLEARRGA
>Mature_225_residues
MQSKRPGLGHMTRAEAAAEELRRRILAGEIAEGTPLKQDALAAEFGISRIPLREALVQLESEGLVRILPHKGAIVAEFSI
DEITELFELRALLEPMLLRKSVPHLDADDFAAIQQVLDAFSDELHANAPAHWGELNTQLHQLLLARANQPRTAGIVHSLL
QQTDRHTRVQLSLTAQSADRAEREHAELVERCRQRDAEGAAALLKAHIEHVGDELKRFLEARRGA

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787821, Length=198, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25013; Mature: 25013

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKRPGLGHMTRAEAAAEELRRRILAGEIAEGTPLKQDALAAEFGISRIPLREALVQLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
SEGLVRILPHKGAIVAEFSIDEITELFELRALLEPMLLRKSVPHLDADDFAAIQQVLDAF
CCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SDELHANAPAHWGELNTQLHQLLLARANQPRTAGIVHSLLQQTDRHTRVQLSLTAQSADR
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHEEEEEEEHHHHHH
AEREHAELVERCRQRDAEGAAALLKAHIEHVGDELKRFLEARRGA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSKRPGLGHMTRAEAAAEELRRRILAGEIAEGTPLKQDALAAEFGISRIPLREALVQLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
SEGLVRILPHKGAIVAEFSIDEITELFELRALLEPMLLRKSVPHLDADDFAAIQQVLDAF
CCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SDELHANAPAHWGELNTQLHQLLLARANQPRTAGIVHSLLQQTDRHTRVQLSLTAQSADR
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHEEEEEEEHHHHHH
AEREHAELVERCRQRDAEGAAALLKAHIEHVGDELKRFLEARRGA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377; 2419835; 8510140 [H]