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The map label for this gene is rspB [H]

Identifier: 238023671

GI number: 238023671

Start: 220176

End: 221210

Strand: Direct

Name: rspB [H]

Synonym: bglu_2g01920

Alternate gene names: 238023671

Gene position: 220176-221210 (Clockwise)

Preceding gene: 238023670

Following gene: 238023675

Centisome position: 7.79

GC content: 70.53

Gene sequence:

>1035_bases
ATGCTGAGCGTCGTGGTCGATCGTCCGAACAGCCTGAGCGTGCGCGAAATGCCGCTGCCCCAGCCCGCTGCGGGCGAGGT
GCGCGTGCGGGTGCGTTACGCGGGCGTTTGCGGCTCGGACCTGCACATCTATCGCGGGCACAACCCGTTCGTTTCATATC
CGCGCATCATCGGCCACGAGTTCGTGGGCCGCGTCGAGGCGCTAGGCGAAGGCGTGGACGCCACGCGCCTAGGCGAGCTG
GTGGCCGTCGATCCCGTGATCAGCTGTGGCCGGTGCCAGGCCTGCCGGATCGGCCGCCGCAACGTGTGCCGCAAGCTGGT
GGTGCTCGGCGTGCATCGCGACGGCGGTTTCAGCGAGTATGTCTGCGTGCCCGCTGCCAATGCCTACCGGATTCCCGAGG
GCATCGCCGACAGCTGCGCGGCCGTCGTCGAGCCGTTCGCGGTGGCCGCCAACGCGACCGCACGCACCGGCGTGCTGCCC
GGCGACGTGGCGCTCGTCTATGGTGCCGGCACCGTCGGGCTGACGATCCTGCAGGTGCTCAAGCGCGTGTACGGCGTGCG
CGCCTTCATCACCGACCGCCTCGACGAGCGGCTCGCGCTGGCGCGCCGCTGCGGCGCGGCCGAAGACGAAACCATCAACG
CCGGCGAGGAAGCGATCGGCGAGGCGCTGGAAAAGCGCGGCGTGGAGGGCGGCCCGACGCTGATCTTCGACGCGGTCGGC
CATCCGTCGATCCTCGAGGAGGCGGTGCGGCTCGCGGCGCCGGCGGGCCGCATCGGGCTGCTCGGCTTCTCGTCCACGCC
GTCGTCGGTCGCGCAGCAGGAGCTGACCAAGAAGGAGCTGACGCTGGCCGCCTCGCGCCTGAACTGCGCGATGTTCCCGA
CCGTGATCGGCTGGCTCGAGCGCGCGCTCGTGACGCCTGAGTCGATCGTCACGCACAAGGTGGATTTCCGCGAGGTGGGG
CGCGCGCTGGAGCTGGCCGAACAGAGCCCGAAGAACGCCTGCAAGGTGCTGCTCGACTTCGCGCCGCAGGGCTGA

Upstream 100 bases:

>100_bases
TATCTGCCGGTCGCGCGGCTGCGCGACGGCGCAATGTGGAACTGGTGAGCGCCGCCGCGCGCGCCCCATCTCCAACGCCT
TCAACACCGAGGAACCTGAC

Downstream 100 bases:

>100_bases
GCGGCGCGGTTCCGCCGTTGTGCGGCGGTGGGCGGCACTGGCGCCGCACTCACTACCCGATCAGATGCACCACCACCTCG
CGCCGGTGCGCGGCGCGGCG

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLSVVVDRPNSLSVREMPLPQPAAGEVRVRVRYAGVCGSDLHIYRGHNPFVSYPRIIGHEFVGRVEALGEGVDATRLGEL
VAVDPVISCGRCQACRIGRRNVCRKLVVLGVHRDGGFSEYVCVPAANAYRIPEGIADSCAAVVEPFAVAANATARTGVLP
GDVALVYGAGTVGLTILQVLKRVYGVRAFITDRLDERLALARRCGAAEDETINAGEEAIGEALEKRGVEGGPTLIFDAVG
HPSILEEAVRLAAPAGRIGLLGFSSTPSSVAQQELTKKELTLAASRLNCAMFPTVIGWLERALVTPESIVTHKVDFREVG
RALELAEQSPKNACKVLLDFAPQG

Sequences:

>Translated_344_residues
MLSVVVDRPNSLSVREMPLPQPAAGEVRVRVRYAGVCGSDLHIYRGHNPFVSYPRIIGHEFVGRVEALGEGVDATRLGEL
VAVDPVISCGRCQACRIGRRNVCRKLVVLGVHRDGGFSEYVCVPAANAYRIPEGIADSCAAVVEPFAVAANATARTGVLP
GDVALVYGAGTVGLTILQVLKRVYGVRAFITDRLDERLALARRCGAAEDETINAGEEAIGEALEKRGVEGGPTLIFDAVG
HPSILEEAVRLAAPAGRIGLLGFSSTPSSVAQQELTKKELTLAASRLNCAMFPTVIGWLERALVTPESIVTHKVDFREVG
RALELAEQSPKNACKVLLDFAPQG
>Mature_344_residues
MLSVVVDRPNSLSVREMPLPQPAAGEVRVRVRYAGVCGSDLHIYRGHNPFVSYPRIIGHEFVGRVEALGEGVDATRLGEL
VAVDPVISCGRCQACRIGRRNVCRKLVVLGVHRDGGFSEYVCVPAANAYRIPEGIADSCAAVVEPFAVAANATARTGVLP
GDVALVYGAGTVGLTILQVLKRVYGVRAFITDRLDERLALARRCGAAEDETINAGEEAIGEALEKRGVEGGPTLIFDAVG
HPSILEEAVRLAAPAGRIGLLGFSSTPSSVAQQELTKKELTLAASRLNCAMFPTVIGWLERALVTPESIVTHKVDFREVG
RALELAEQSPKNACKVLLDFAPQG

Specific function: Not known; probable catabolic enzyme [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=351, Percent_Identity=28.4900284900285, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI71565154, Length=347, Percent_Identity=25.6484149855908, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI262073058, Length=356, Percent_Identity=24.7191011235955, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI156523966, Length=365, Percent_Identity=25.2054794520548, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI71743840, Length=356, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501939, Length=354, Percent_Identity=25.1412429378531, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4501933, Length=261, Percent_Identity=27.2030651340996, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4501929, Length=264, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI34577061, Length=261, Percent_Identity=27.2030651340996, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787863, Length=342, Percent_Identity=55.8479532163743, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI226510992, Length=334, Percent_Identity=31.7365269461078, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1790045, Length=337, Percent_Identity=29.3768545994065, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788073, Length=339, Percent_Identity=27.1386430678466, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788407, Length=334, Percent_Identity=29.6407185628743, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790718, Length=348, Percent_Identity=26.4367816091954, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786825, Length=392, Percent_Identity=27.5510204081633, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082125, Length=356, Percent_Identity=25.561797752809, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788075, Length=345, Percent_Identity=24.3478260869565, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081918, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786552, Length=354, Percent_Identity=25.4237288135593, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786518, Length=122, Percent_Identity=34.4262295081967, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082401, Length=113, Percent_Identity=34.5132743362832, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=341, Percent_Identity=29.0322580645161, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17562878, Length=217, Percent_Identity=34.5622119815668, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71988145, Length=162, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=288, Percent_Identity=26.7361111111111, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562584, Length=216, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25146526, Length=350, Percent_Identity=23.1428571428571, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71997431, Length=352, Percent_Identity=23.0113636363636, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565904, Length=248, Percent_Identity=25, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=353, Percent_Identity=24.3626062322946, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323099, Length=351, Percent_Identity=24.2165242165242, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319955, Length=353, Percent_Identity=24.0793201133144, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320033, Length=364, Percent_Identity=25.5494505494505, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=267, Percent_Identity=27.3408239700375, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319258, Length=220, Percent_Identity=31.3636363636364, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319257, Length=256, Percent_Identity=28.125, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324486, Length=267, Percent_Identity=26.5917602996255, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=271, Percent_Identity=26.5682656826568, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=133, Percent_Identity=31.5789473684211, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323980, Length=132, Percent_Identity=32.5757575757576, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17137530, Length=353, Percent_Identity=26.628895184136, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17737897, Length=361, Percent_Identity=26.0387811634349, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI45550770, Length=329, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45551930, Length=329, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221457811, Length=332, Percent_Identity=25, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737895, Length=367, Percent_Identity=22.3433242506812, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 36629; Mature: 36629

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVVVDRPNSLSVREMPLPQPAAGEVRVRVRYAGVCGSDLHIYRGHNPFVSYPRIIGHE
CEEEEEECCCCCCEECCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
FVGRVEALGEGVDATRLGELVAVDPVISCGRCQACRIGRRNVCRKLVVLGVHRDGGFSEY
HHHHHHHHCCCCCHHHHCCEEEECCHHCCCCCHHHHCCHHHHHHHHHHEEECCCCCCCCE
VCVPAANAYRIPEGIADSCAAVVEPFAVAANATARTGVLPGDVALVYGAGTVGLTILQVL
EEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHH
KRVYGVRAFITDRLDERLALARRCGAAEDETINAGEEAIGEALEKRGVEGGPTLIFDAVG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCC
HPSILEEAVRLAAPAGRIGLLGFSSTPSSVAQQELTKKELTLAASRLNCAMFPTVIGWLE
CHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RALVTPESIVTHKVDFREVGRALELAEQSPKNACKVLLDFAPQG
HHHCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLSVVVDRPNSLSVREMPLPQPAAGEVRVRVRYAGVCGSDLHIYRGHNPFVSYPRIIGHE
CEEEEEECCCCCCEECCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
FVGRVEALGEGVDATRLGELVAVDPVISCGRCQACRIGRRNVCRKLVVLGVHRDGGFSEY
HHHHHHHHCCCCCHHHHCCEEEECCHHCCCCCHHHHCCHHHHHHHHHHEEECCCCCCCCE
VCVPAANAYRIPEGIADSCAAVVEPFAVAANATARTGVLPGDVALVYGAGTVGLTILQVL
EEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHH
KRVYGVRAFITDRLDERLALARRCGAAEDETINAGEEAIGEALEKRGVEGGPTLIFDAVG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCC
HPSILEEAVRLAAPAGRIGLLGFSSTPSSVAQQELTKKELTLAASRLNCAMFPTVIGWLE
CHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RALVTPESIVTHKVDFREVGRALELAEQSPKNACKVLLDFAPQG
HHHCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7545940; 9097039; 9278503 [H]