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The map label for this gene is lldR [H]

Identifier: 238023624

GI number: 238023624

Start: 144816

End: 145547

Strand: Direct

Name: lldR [H]

Synonym: bglu_2g01310

Alternate gene names: 238023624

Gene position: 144816-145547 (Clockwise)

Preceding gene: 238023623

Following gene: 238023625

Centisome position: 5.12

GC content: 63.52

Gene sequence:

>732_bases
ATGTTGATCGACAGCCGGCACCTCAAACCCGGCGACCGCGTACCAGCCGAACGCGATCTTGCCGCAGACCTGGGCGTGTC
CCGTTCAAGCCTGCGAGAAGCCATTCACCAATTGATCAGCCGCGGCCGCCTTGTCAGCCGCCACGGTCAAGGGACTTTCG
TGGCGGCGCCGGACGCCGCCGAGCCCTTGCGCGCGGCTTTGCTTCCCATCGCGCCGCTTGCTCGAAGCGAGACGGGTTAT
TGGGCGGACGTGATGGAGATCCGCAGGTCGCTTGAAGGCGAGGCTGCTTTCTTCGCCGCGCTGCGCGCCAACGCCGACGA
CAAAATGCTGCTGACAGCCGCCTATCGCGCCGCGGCCAATGCTCCGAGCGGCGACCCGGTGATCCACGCCAAAGCGGACG
CGGCATTTCATATGTCGATCGCCCGGGCCTCACACAACGTCGTACTCCATCAGGTCATGTCCGGCTTGCTGGGGCTGCTG
GAGGTCAGCATCTCCGAAAGCCTGCGCAAGCTCTACGGCCTTCCCGGAATCATCGAGCTTCTCGACGGCCAACATCAGCA
GATCTTCGAGTCCATTTTGGGCGGCCGCGTGGACGAGGCCCGTCGTGCCGCCGCCGCGCATCTGAGCTATGTAGAAAGCC
GTCTGCGGCTCATCGATGATATTTCGGCACGTGAGCGTCGCGCTTCGCGAGCTTTTCGACACATTTCCAAAGAGCAAGGA
GAGCGGGCGTGA

Upstream 100 bases:

>100_bases
GACTTCCGTTGTTCTGATGCCCAAGGTTAACAGCTTGCCGAGGAAGTAAACAGCCCCTCTCGGGAGTTTTTGAACTGGCC
TCTTAGCGGAAAAGATAGAG

Downstream 100 bases:

>100_bases
TTATTTCTTCCACACTCGATTATCGCGAGGCAGCCCGGCGTCGCTTGCCCCGGTTTCTATTCGACTATATCGATGGCGGC
GCCTATGCCGAAGACACGCT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MLIDSRHLKPGDRVPAERDLAADLGVSRSSLREAIHQLISRGRLVSRHGQGTFVAAPDAAEPLRAALLPIAPLARSETGY
WADVMEIRRSLEGEAAFFAALRANADDKMLLTAAYRAAANAPSGDPVIHAKADAAFHMSIARASHNVVLHQVMSGLLGLL
EVSISESLRKLYGLPGIIELLDGQHQQIFESILGGRVDEARRAAAAHLSYVESRLRLIDDISARERRASRAFRHISKEQG
ERA

Sequences:

>Translated_243_residues
MLIDSRHLKPGDRVPAERDLAADLGVSRSSLREAIHQLISRGRLVSRHGQGTFVAAPDAAEPLRAALLPIAPLARSETGY
WADVMEIRRSLEGEAAFFAALRANADDKMLLTAAYRAAANAPSGDPVIHAKADAAFHMSIARASHNVVLHQVMSGLLGLL
EVSISESLRKLYGLPGIIELLDGQHQQIFESILGGRVDEARRAAAAHLSYVESRLRLIDDISARERRASRAFRHISKEQG
ERA
>Mature_243_residues
MLIDSRHLKPGDRVPAERDLAADLGVSRSSLREAIHQLISRGRLVSRHGQGTFVAAPDAAEPLRAALLPIAPLARSETGY
WADVMEIRRSLEGEAAFFAALRANADDKMLLTAAYRAAANAPSGDPVIHAKADAAFHMSIARASHNVVLHQVMSGLLGLL
EVSISESLRKLYGLPGIIELLDGQHQQIFESILGGRVDEARRAAAAHLSYVESRLRLIDDISARERRASRAFRHISKEQG
ERA

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=229, Percent_Identity=39.3013100436681, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1786303, Length=212, Percent_Identity=35.8490566037736, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789353, Length=216, Percent_Identity=32.4074074074074, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790780, Length=237, Percent_Identity=27.0042194092827, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26473; Mature: 26473

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSRHLKPGDRVPAERDLAADLGVSRSSLREAIHQLISRGRLVSRHGQGTFVAAPDAA
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEHCCCCCCEEECCCCH
EPLRAALLPIAPLARSETGYWADVMEIRRSLEGEAAFFAALRANADDKMLLTAAYRAAAN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
APSGDPVIHAKADAAFHMSIARASHNVVLHQVMSGLLGLLEVSISESLRKLYGLPGIIEL
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LDGQHQQIFESILGGRVDEARRAAAAHLSYVESRLRLIDDISARERRASRAFRHISKEQG
HCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ERA
CCC
>Mature Secondary Structure
MLIDSRHLKPGDRVPAERDLAADLGVSRSSLREAIHQLISRGRLVSRHGQGTFVAAPDAA
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEHCCCCCCEEECCCCH
EPLRAALLPIAPLARSETGYWADVMEIRRSLEGEAAFFAALRANADDKMLLTAAYRAAAN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
APSGDPVIHAKADAAFHMSIARASHNVVLHQVMSGLLGLLEVSISESLRKLYGLPGIIEL
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LDGQHQQIFESILGGRVDEARRAAAAHLSYVESRLRLIDDISARERRASRAFRHISKEQG
HCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ERA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]