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The map label for this gene is lldD [H]

Identifier: 238023625

GI number: 238023625

Start: 145544

End: 146707

Strand: Direct

Name: lldD [H]

Synonym: bglu_2g01320

Alternate gene names: 238023625

Gene position: 145544-146707 (Clockwise)

Preceding gene: 238023624

Following gene: 238023626

Centisome position: 5.15

GC content: 60.65

Gene sequence:

>1164_bases
GTGATTATTTCTTCCACACTCGATTATCGCGAGGCAGCCCGGCGTCGCTTGCCCCGGTTTCTATTCGACTATATCGATGG
CGGCGCCTATGCCGAAGACACGCTGCGGCGCAACTCGGAGGACCTGCGGGCGCTTGCCTTGCGCCAGAAAGTGCTCAAGG
AGGTTGGCGATGTCGATCTCTCCACGCGGATCTTCGGCCAACAACTGGCTCTGCCCGTGGCGCTCGGGCCGGTCGGTCTT
ACCGGAATGTATGCACGCCGCGGTGAGGTGCAAGCGGCACGGGCAGCCTCCGCCAAGGGCGTGCCCTTCACGCTGTCCAC
CGTTGGCGTTTGCTCGATCGAGGAGGTGCAGTCGCAGGTGGCACGACCGATCTGGTTCCAGCTATACGTGCTCAAGGATC
GCGGCTTCATGAAAAACGTGCTTGAGCGAGCTTGGGCAGTCGGAATACGTACCCTTGTATTCACCGTCGACATGCCTGTC
CCCGGCGCACGATACCGAGACAAGCATTCCGGCATGTCAGGCCCTCACGCCGCGATCCGCCGCTATTGGCAGTCGGTCTT
TCATCCGCACTGGGCCACGGCAGTCGGACTGCTGGGAATGCCTCACGATCTTGGAAACGTCTCGGCGTATCTGAAGCGTC
GAAGCAAGCTTGATGACTATGTCGGTTGGCTGGGTGCGAATTTCGATCCCACCATTGGCTGGCGCGATCTTCAGTGGATC
AGAGACTTCTGGAAGGGATCGATGATCCTGAAAGGCATTCTCGATCCGCTCGATGCGCGGGATGCGGTGAAGTTTGGTGC
GGACGGCATCGTCGTTTCAAATCACGGCGGCCGCCAGCTCGATGGCGTGCTATCGACGGCTAGGGCCCTGCCCACCATAG
CCGATGCGGTCAAAAAGGAAATCACCGTCCTGGTCGATTCCGGAGTCCGCTCCGGCCTCGACGTGGTGCGCATGTTGGCG
CTGGGCGCCGACACTGTTCTGCTCGGACGGGCCTATATATACGCGCTTGCCAGCGCCGGAGAGCGCGGTGTCGCTCATCT
TCTCGATCTGATCCGCAACGAAATGCGGGTTGCAATGACCCTGACCGGCGCGCGCTCGATTGCCGACATAAGCCGCTCTA
ACCTGGTGTCTCCCGGACTCGAAACCATGGAGCTTGCAGCATGA

Upstream 100 bases:

>100_bases
ATGTAGAAAGCCGTCTGCGGCTCATCGATGATATTTCGGCACGTGAGCGTCGCGCTTCGCGAGCTTTTCGACACATTTCC
AAAGAGCAAGGAGAGCGGGC

Downstream 100 bases:

>100_bases
CGATGACCAATGCAGATCTGTTGACGCGCACACTTGCCAACGCAGGCGTTCAACGTATTTGGGGTGTGACCGGCGACAGC
CTGAACGGTCTGAACGACAG

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MIISSTLDYREAARRRLPRFLFDYIDGGAYAEDTLRRNSEDLRALALRQKVLKEVGDVDLSTRIFGQQLALPVALGPVGL
TGMYARRGEVQAARAASAKGVPFTLSTVGVCSIEEVQSQVARPIWFQLYVLKDRGFMKNVLERAWAVGIRTLVFTVDMPV
PGARYRDKHSGMSGPHAAIRRYWQSVFHPHWATAVGLLGMPHDLGNVSAYLKRRSKLDDYVGWLGANFDPTIGWRDLQWI
RDFWKGSMILKGILDPLDARDAVKFGADGIVVSNHGGRQLDGVLSTARALPTIADAVKKEITVLVDSGVRSGLDVVRMLA
LGADTVLLGRAYIYALASAGERGVAHLLDLIRNEMRVAMTLTGARSIADISRSNLVSPGLETMELAA

Sequences:

>Translated_387_residues
MIISSTLDYREAARRRLPRFLFDYIDGGAYAEDTLRRNSEDLRALALRQKVLKEVGDVDLSTRIFGQQLALPVALGPVGL
TGMYARRGEVQAARAASAKGVPFTLSTVGVCSIEEVQSQVARPIWFQLYVLKDRGFMKNVLERAWAVGIRTLVFTVDMPV
PGARYRDKHSGMSGPHAAIRRYWQSVFHPHWATAVGLLGMPHDLGNVSAYLKRRSKLDDYVGWLGANFDPTIGWRDLQWI
RDFWKGSMILKGILDPLDARDAVKFGADGIVVSNHGGRQLDGVLSTARALPTIADAVKKEITVLVDSGVRSGLDVVRMLA
LGADTVLLGRAYIYALASAGERGVAHLLDLIRNEMRVAMTLTGARSIADISRSNLVSPGLETMELAA
>Mature_387_residues
MIISSTLDYREAARRRLPRFLFDYIDGGAYAEDTLRRNSEDLRALALRQKVLKEVGDVDLSTRIFGQQLALPVALGPVGL
TGMYARRGEVQAARAASAKGVPFTLSTVGVCSIEEVQSQVARPIWFQLYVLKDRGFMKNVLERAWAVGIRTLVFTVDMPV
PGARYRDKHSGMSGPHAAIRRYWQSVFHPHWATAVGLLGMPHDLGNVSAYLKRRSKLDDYVGWLGANFDPTIGWRDLQWI
RDFWKGSMILKGILDPLDARDAVKFGADGIVVSNHGGRQLDGVLSTARALPTIADAVKKEITVLVDSGVRSGLDVVRMLA
LGADTVLLGRAYIYALASAGERGVAHLLDLIRNEMRVAMTLTGARSIADISRSNLVSPGLETMELAA

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=370, Percent_Identity=34.3243243243243, Blast_Score=221, Evalue=6e-58,
Organism=Homo sapiens, GI54234014, Length=380, Percent_Identity=36.0526315789474, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI7705393, Length=380, Percent_Identity=36.0526315789474, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1790033, Length=376, Percent_Identity=71.0106382978723, Blast_Score=565, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI193208036, Length=367, Percent_Identity=33.5149863760218, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI32566217, Length=283, Percent_Identity=31.8021201413428, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323587, Length=382, Percent_Identity=28.5340314136126, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363140, Length=377, Percent_Identity=35.0132625994695, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI78707190, Length=377, Percent_Identity=35.0132625994695, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI78707188, Length=377, Percent_Identity=35.0132625994695, Blast_Score=215, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42487; Mature: 42487

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISSTLDYREAARRRLPRFLFDYIDGGAYAEDTLRRNSEDLRALALRQKVLKEVGDVDL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
STRIFGQQLALPVALGPVGLTGMYARRGEVQAARAASAKGVPFTLSTVGVCSIEEVQSQV
HHHHHHHHHHHHHEECCCCCCHHHHHCCCHHHHHHCCCCCCCEEEHHCCCCCHHHHHHHH
ARPIWFQLYVLKDRGFMKNVLERAWAVGIRTLVFTVDMPVPGARYRDKHSGMSGPHAAIR
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHCCCCCCHHHHHH
RYWQSVFHPHWATAVGLLGMPHDLGNVSAYLKRRSKLDDYVGWLGANFDPTIGWRDLQWI
HHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RDFWKGSMILKGILDPLDARDAVKFGADGIVVSNHGGRQLDGVLSTARALPTIADAVKKE
HHHHCCHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ITVLVDSGVRSGLDVVRMLALGADTVLLGRAYIYALASAGERGVAHLLDLIRNEMRVAMT
HHHEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEE
LTGARSIADISRSNLVSPGLETMELAA
ECCCHHHHHHHHHCCCCCCCHHHHHCC
>Mature Secondary Structure
MIISSTLDYREAARRRLPRFLFDYIDGGAYAEDTLRRNSEDLRALALRQKVLKEVGDVDL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
STRIFGQQLALPVALGPVGLTGMYARRGEVQAARAASAKGVPFTLSTVGVCSIEEVQSQV
HHHHHHHHHHHHHEECCCCCCHHHHHCCCHHHHHHCCCCCCCEEEHHCCCCCHHHHHHHH
ARPIWFQLYVLKDRGFMKNVLERAWAVGIRTLVFTVDMPVPGARYRDKHSGMSGPHAAIR
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHCCCCCCHHHHHH
RYWQSVFHPHWATAVGLLGMPHDLGNVSAYLKRRSKLDDYVGWLGANFDPTIGWRDLQWI
HHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RDFWKGSMILKGILDPLDARDAVKFGADGIVVSNHGGRQLDGVLSTARALPTIADAVKKE
HHHHCCHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ITVLVDSGVRSGLDVVRMLALGADTVLLGRAYIYALASAGERGVAHLLDLIRNEMRVAMT
HHHEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEE
LTGARSIADISRSNLVSPGLETMELAA
ECCCHHHHHHHHHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA