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The map label for this gene is tcp [H]

Identifier: 238023607

GI number: 238023607

Start: 120571

End: 122214

Strand: Direct

Name: tcp [H]

Synonym: bglu_2g01120

Alternate gene names: 238023607

Gene position: 120571-122214 (Clockwise)

Preceding gene: 238023602

Following gene: 238023609

Centisome position: 4.26

GC content: 67.21

Gene sequence:

>1644_bases
ATGGAAAAAATGAAAGTTTCGACCCGCCTCGCCCTGGGTTTCGGGCTTGTGTTGTTTCTGCTCCTGCTGATTTCGGCAGG
TGCCTATCACGCCGAGCGTACGCTCGCAGCGAGCCTGTACGAAATCACCTCGCTGAACAACGTGGAGGCAAGACTGGCGA
ACCGCATGAAATCCACCGTGCGAGACCGCGCCATCGCCGTTCGCAACGTGGCGCTGTCGACCGATCCGGCCGAGCGCGAC
CGGCAGAGCGCACGCATCGACAAGCAGGAACAGGCTTATGCCGATGCGTACGCGAAGCTGGCCTCGGTCTTTGCCCGGGA
GCCATCGATTTCAGACCGCGAGCGGGATCTACTCGCCAAGCTGAAGGATGACGAGGCGGCCACGAAGCCCCTATGGGCCA
AGGCGGTCGCCCTGGGCAGGGCCAACGATAATGCCGGCATGATCCGGGTCTTGACGGGCGAGGCCCGTCGGCCATCAAAC
ACCTGGATTGCGCGACTCGATGAACTCGCCGATATCGAGGATGCCCAAAACGACCAGGCGGCCCAGGCGGCCCAGGCGAG
CTCGGAGCGCATGCAGGCGGCGACATGGACGTTCGTCGCGCTGGCATTGGCCGTCGGCTCGCTCGCCGCCTTTTTCATCA
CGCGCGGCATCCTGAGGCAATTGGGCGGCGAGCCGGCCGCGGCGCAGGAGGTGGCGCGCCGCATCGCGGCCGGCGATCTG
ACCGTGAGCCTGCAGATCGAGGAGGGCGATACGCACAGCCTGATGGCATCGCTCGAGTCGATGCGGGGGCGACTGGGTGA
AATGGTGGCGGACATCAAGGCATCGGCCGAATCGATCGCGGTTGCCGCTGGCGAAATCGCGCAAGGCAACGTCGACCTCT
CGCAGCGCACCGAGGAGCAGGCGGCCTCGCTGGAGGAAACCGCGGCGAGCATGGAGCAGTTGACCTCGGCGGTCCGGCAG
AACACCGACAACGCCCGCAAGGGCAGCTCGCTGGCCGCGAATGCGTCGGCTACGGCCACCGCCGGCGGTGATGTCGTGAA
CAGGGTGGTGTCGACGATGGAGGACATTTCCTCGAGTTCGCTGCGCGTGGCCGAGATCATCGCGGTGATCGAAGGCATCG
CGTTCCAGACCAATATCCTGGCGCTCAACGCGGCGGTGGAGGCGGCGCGAGCCGGCGAGCAGGGGCGGGGCTTCGCGGTG
GTGGCGGGCGAGGTGCGCACGCTGGCGCAGCGCAGCGCGACGGCGGCCAAGGAGATCAAGGATCTGATCAGCGCGTCGGT
GGAGCATGTGGGCACGGGCTCGCGACTGGTGCGGGAGGCGGGCTCGACGATGACCGACGTGGTGCGCTCGGTGCAGCAGG
TGACCGACATCATCGAGGAAGTGGCCTCGGCATCGACGGAGCAGGGCAGGGGGATCGAGCAGGTGAACGTGGCGGTCAGT
CAAATGGACGAGGTCACGCAGCAAAACGCGGCGCTGGTGGAGCAGGCCTCGGCCTCGGCGCAAGCGCTGGCCGATCAGGC
AGGGGTGCTGCGCCAGGCGGTTGCGGTGTTTCGGATCGAGGCCGCCAAGCCGAGCCGGCAGGCGCCGGCCGCCCCGGCAC
CGAGCGCGATGCCGCGATTGAGCCGCGGCGGGCTGGCAGCGTAA

Upstream 100 bases:

>100_bases
TTTGAAAAATATACACGCGTATAAATTTTCTAAATTTTCCAGTTTTCAGGACGTAATCAAGGGTGACTCGTTGGCTCCCC
CACCAGACTGAAGACAGAAA

Downstream 100 bases:

>100_bases
CGGTGCCGGCCGGCCGCCGCCGGAATGCGTAACAGGATCACCGGAGGCGTCCCCGCATCCGAATCGCCCGATATCCGCCG
CATGGTCGATGCGGCGCGGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MEKMKVSTRLALGFGLVLFLLLLISAGAYHAERTLAASLYEITSLNNVEARLANRMKSTVRDRAIAVRNVALSTDPAERD
RQSARIDKQEQAYADAYAKLASVFAREPSISDRERDLLAKLKDDEAATKPLWAKAVALGRANDNAGMIRVLTGEARRPSN
TWIARLDELADIEDAQNDQAAQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQAASLEETAASMEQLTSAVRQ
NTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSSLRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSATAAKEIKDLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGRGIEQVNVAVS
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRLSRGGLAA

Sequences:

>Translated_547_residues
MEKMKVSTRLALGFGLVLFLLLLISAGAYHAERTLAASLYEITSLNNVEARLANRMKSTVRDRAIAVRNVALSTDPAERD
RQSARIDKQEQAYADAYAKLASVFAREPSISDRERDLLAKLKDDEAATKPLWAKAVALGRANDNAGMIRVLTGEARRPSN
TWIARLDELADIEDAQNDQAAQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQAASLEETAASMEQLTSAVRQ
NTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSSLRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSATAAKEIKDLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGRGIEQVNVAVS
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRLSRGGLAA
>Mature_547_residues
MEKMKVSTRLALGFGLVLFLLLLISAGAYHAERTLAASLYEITSLNNVEARLANRMKSTVRDRAIAVRNVALSTDPAERD
RQSARIDKQEQAYADAYAKLASVFAREPSISDRERDLLAKLKDDEAATKPLWAKAVALGRANDNAGMIRVLTGEARRPSN
TWIARLDELADIEDAQNDQAAQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQAASLEETAASMEQLTSAVRQ
NTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSSLRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSATAAKEIKDLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGRGIEQVNVAVS
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRLSRGGLAA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=380, Percent_Identity=53.1578947368421, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788195, Length=319, Percent_Identity=58.307210031348, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788194, Length=367, Percent_Identity=50.408719346049, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1787690, Length=382, Percent_Identity=49.4764397905759, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1789453, Length=260, Percent_Identity=41.9230769230769, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57556; Mature: 57556

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS00368 RIBORED_SMALL ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKMKVSTRLALGFGLVLFLLLLISAGAYHAERTLAASLYEITSLNNVEARLANRMKSTV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RDRAIAVRNVALSTDPAERDRQSARIDKQEQAYADAYAKLASVFAREPSISDRERDLLAK
HHHHHHHHHHEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LKDDEAATKPLWAKAVALGRANDNAGMIRVLTGEARRPSNTWIARLDELADIEDAQNDQA
HCCCHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHH
AQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCE
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AASLEETAASMEQLTSAVRQNTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGRGIEQVNVAVS
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SRGGLAA
CCCCCCC
>Mature Secondary Structure
MEKMKVSTRLALGFGLVLFLLLLISAGAYHAERTLAASLYEITSLNNVEARLANRMKSTV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RDRAIAVRNVALSTDPAERDRQSARIDKQEQAYADAYAKLASVFAREPSISDRERDLLAK
HHHHHHHHHHEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LKDDEAATKPLWAKAVALGRANDNAGMIRVLTGEARRPSNTWIARLDELADIEDAQNDQA
HCCCHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHH
AQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCE
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AASLEETAASMEQLTSAVRQNTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGRGIEQVNVAVS
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SRGGLAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]