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The map label for this gene is tcp [H]

Identifier: 238023604

GI number: 238023604

Start: 113022

End: 114572

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g01070

Alternate gene names: 238023604

Gene position: 114572-113022 (Counterclockwise)

Preceding gene: 238023605

Following gene: 238023603

Centisome position: 4.05

GC content: 66.73

Gene sequence:

>1551_bases
TTGCGCACTCAGTTCGTGCTGCTGATCCTCGGGTTCTCGTCCTGTTTCATCGCGTACAGCCTGTGCTCGCTCTTCGTGTT
GAAAGAGCTGCGCGTCAACGGCCCCTTGTATCAGAAGATCCAGCTGAGCAACGATCTGGTCTCCGATATCCTGCCGCCGC
CCGAATACGTGATCGAGTCGTACCTGCTGTGCTTCCAGCTGCTCGACGCGGACGCCGTGCAACAGCCGCGCTTGATCGAC
CGTCTCGCCTCGCTGAGAAAGGACTATGACGATCGCTATCGATTCTGGAGCGAGCAGCCGCTCAATCCGGACACGCGGCG
GGCGCTGATCGACGCATCTCACCCTCCCGCCGTCGCGTTCTACCGGATCGTCTTCGACGACTTCATTCCCGCGGTGCAGC
GCGAGGACAAGGTCGCGGCGCGCGACGCACTGGGCCGCATTTCCCAGCAGTACGATCTGCAGCGCAAGGCAATCGACAGC
CTGGTGCAACTGGCCACGCGCGACACCTCGGCGGTCGAGGCCGAGGCACGGCGGGGCACCCAGTCCAGCTTCTGGCTGCT
GGCCGGCGTATTCGGGCTCGCGCTGGCGGTGAGCATACTGATGACGCATTTCATGGCGAGACGGCTGCAGTCCCAGCTGG
GCGGCGAGCCCGCGCTCGCCACGCATGTGGCCAACCATATCGCCGCGGGCGACCTGACCGTCGACATCGGCTCGGCACCC
GCCGTCTCGCGGAGCCTGCTGGCGGCCATGCAGGCCATGCAGGCCATGCAGGCGAACCTGACGAGGATGGTGGCCGACGT
GCGCGCCGTCACCCAGAGCGTGGCGGCCGCGGCCGGCGAGATCGTCGGCGGCAACAGCGAGCTGTCGACGCGCTCCGGCC
AGCAGGCCGCCTCGCTCGAGGAAACCGCGGCCAGCGTGACGCAGCTGACCGAGACGGTCAAACAGAACGCCGACAACGCG
CGTCAAGCCAATGCGCTGGCCACCCAGGCCACGAACATGGCCGATGTCGGCGACACCGCCGTGCAGCGCATGGTCGGCTC
GATCGAAAAGATCAGCGGCAGCTCGAACAAGATTTCCGAGATCACCGGCGTCATCGAGAGCATCGCGTTCCAGACCAATA
TCCTCGCGCTGAACGCCGCGGTGGAAGCGGCACGGGCCGGCGAACAGGGACGCGGGTTCGCGGTGGTGGCCAGCGAGGTA
CGCAGCCTCGCGCAGCGCTCGGCGGCGGCCGCCAAGGAGATCAAGGCGCTGATCGAAGCCTCGGTCACGACGATCGAGGA
CGGCGCCCGGCAGGCGAACGACGTCGGCACGACGGTGGGCGAGGTCAGGCAGGCGATCAAGCGCGTCTCCGATCTGATCG
GCGAGATCGCGGCGGCCTCCGACGAGCAGAGCCGCGGCATCGAGCAGGTCAACCAGGCAGTCAACCAGATCGAGGACATC
ACGCGTCGCAACGCGGATCTGTTCGAGCAGGCCACCGGCTCGGCCCAGTCGCTCGAAAGGCAGGCGGTCCGGCTCACGAC
CGCCGTGTCGGCCTTCAAGCTGATGGCTTGA

Upstream 100 bases:

>100_bases
AAAATGAAGATTCGCGCTCGCCTTGGCCGCGGCCTCGGCATTTCCATGTAGTTTTCGTGAGGCGGAAAGATTGTCATCAA
TGAGTCATAAGACGTTTCGC

Downstream 100 bases:

>100_bases
GCATGGGCAGCGAGCCGCCAATCCCAAGGCTGAACTGATGCACGCGGTGCTGTCCGAATTGCTATTCAAGGTACTTGCCT
ATCTGGCTCCAGCGGAGATG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MRTQFVLLILGFSSCFIAYSLCSLFVLKELRVNGPLYQKIQLSNDLVSDILPPPEYVIESYLLCFQLLDADAVQQPRLID
RLASLRKDYDDRYRFWSEQPLNPDTRRALIDASHPPAVAFYRIVFDDFIPAVQREDKVAARDALGRISQQYDLQRKAIDS
LVQLATRDTSAVEAEARRGTQSSFWLLAGVFGLALAVSILMTHFMARRLQSQLGGEPALATHVANHIAAGDLTVDIGSAP
AVSRSLLAAMQAMQAMQANLTRMVADVRAVTQSVAAAAGEIVGGNSELSTRSGQQAASLEETAASVTQLTETVKQNADNA
RQANALATQATNMADVGDTAVQRMVGSIEKISGSSNKISEITGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEV
RSLAQRSAAAAKEIKALIEASVTTIEDGARQANDVGTTVGEVRQAIKRVSDLIGEIAAASDEQSRGIEQVNQAVNQIEDI
TRRNADLFEQATGSAQSLERQAVRLTTAVSAFKLMA

Sequences:

>Translated_516_residues
MRTQFVLLILGFSSCFIAYSLCSLFVLKELRVNGPLYQKIQLSNDLVSDILPPPEYVIESYLLCFQLLDADAVQQPRLID
RLASLRKDYDDRYRFWSEQPLNPDTRRALIDASHPPAVAFYRIVFDDFIPAVQREDKVAARDALGRISQQYDLQRKAIDS
LVQLATRDTSAVEAEARRGTQSSFWLLAGVFGLALAVSILMTHFMARRLQSQLGGEPALATHVANHIAAGDLTVDIGSAP
AVSRSLLAAMQAMQAMQANLTRMVADVRAVTQSVAAAAGEIVGGNSELSTRSGQQAASLEETAASVTQLTETVKQNADNA
RQANALATQATNMADVGDTAVQRMVGSIEKISGSSNKISEITGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEV
RSLAQRSAAAAKEIKALIEASVTTIEDGARQANDVGTTVGEVRQAIKRVSDLIGEIAAASDEQSRGIEQVNQAVNQIEDI
TRRNADLFEQATGSAQSLERQAVRLTTAVSAFKLMA
>Mature_516_residues
MRTQFVLLILGFSSCFIAYSLCSLFVLKELRVNGPLYQKIQLSNDLVSDILPPPEYVIESYLLCFQLLDADAVQQPRLID
RLASLRKDYDDRYRFWSEQPLNPDTRRALIDASHPPAVAFYRIVFDDFIPAVQREDKVAARDALGRISQQYDLQRKAIDS
LVQLATRDTSAVEAEARRGTQSSFWLLAGVFGLALAVSILMTHFMARRLQSQLGGEPALATHVANHIAAGDLTVDIGSAP
AVSRSLLAAMQAMQAMQANLTRMVADVRAVTQSVAAAAGEIVGGNSELSTRSGQQAASLEETAASVTQLTETVKQNADNA
RQANALATQATNMADVGDTAVQRMVGSIEKISGSSNKISEITGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEV
RSLAQRSAAAAKEIKALIEASVTTIEDGARQANDVGTTVGEVRQAIKRVSDLIGEIAAASDEQSRGIEQVNQAVNQIEDI
TRRNADLFEQATGSAQSLERQAVRLTTAVSAFKLMA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=342, Percent_Identity=49.1228070175439, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI2367378, Length=366, Percent_Identity=47.8142076502732, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788194, Length=288, Percent_Identity=51.7361111111111, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1788195, Length=266, Percent_Identity=56.015037593985, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1789453, Length=251, Percent_Identity=39.0438247011952, Blast_Score=173, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55497; Mature: 55497

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTQFVLLILGFSSCFIAYSLCSLFVLKELRVNGPLYQKIQLSNDLVSDILPPPEYVIES
CCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
YLLCFQLLDADAVQQPRLIDRLASLRKDYDDRYRFWSEQPLNPDTRRALIDASHPPAVAF
HHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHH
YRIVFDDFIPAVQREDKVAARDALGRISQQYDLQRKAIDSLVQLATRDTSAVEAEARRGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
QSSFWLLAGVFGLALAVSILMTHFMARRLQSQLGGEPALATHVANHIAAGDLTVDIGSAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCC
AVSRSLLAAMQAMQAMQANLTRMVADVRAVTQSVAAAAGEIVGGNSELSTRSGQQAASLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ETAASVTQLTETVKQNADNARQANALATQATNMADVGDTAVQRMVGSIEKISGSSNKISE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHCCCCCHHHH
ITGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSAAAAKEIKALIEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTTIEDGARQANDVGTTVGEVRQAIKRVSDLIGEIAAASDEQSRGIEQVNQAVNQIEDI
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHH
TRRNADLFEQATGSAQSLERQAVRLTTAVSAFKLMA
HHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTQFVLLILGFSSCFIAYSLCSLFVLKELRVNGPLYQKIQLSNDLVSDILPPPEYVIES
CCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
YLLCFQLLDADAVQQPRLIDRLASLRKDYDDRYRFWSEQPLNPDTRRALIDASHPPAVAF
HHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHH
YRIVFDDFIPAVQREDKVAARDALGRISQQYDLQRKAIDSLVQLATRDTSAVEAEARRGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
QSSFWLLAGVFGLALAVSILMTHFMARRLQSQLGGEPALATHVANHIAAGDLTVDIGSAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCC
AVSRSLLAAMQAMQAMQANLTRMVADVRAVTQSVAAAAGEIVGGNSELSTRSGQQAASLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ETAASVTQLTETVKQNADNARQANALATQATNMADVGDTAVQRMVGSIEKISGSSNKISE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHCCCCCHHHH
ITGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSAAAAKEIKALIEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTTIEDGARQANDVGTTVGEVRQAIKRVSDLIGEIAAASDEQSRGIEQVNQAVNQIEDI
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHH
TRRNADLFEQATGSAQSLERQAVRLTTAVSAFKLMA
HHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]