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The map label for this gene is tcp [H]

Identifier: 238023603

GI number: 238023603

Start: 110914

End: 112539

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g01060

Alternate gene names: 238023603

Gene position: 112539-110914 (Counterclockwise)

Preceding gene: 238023604

Following gene: 238023598

Centisome position: 3.98

GC content: 67.96

Gene sequence:

>1626_bases
ATGAACCACCTGCATCAGACAGTCCGTTTCAAAATCGTGGCGGCGATGACCGCCTGCGTGCTCGTCATCGCGTTCATTGG
CGTGTACGGCTCGCTGACCATCGCGCGGCTCGAGCATATCGTCCGCAGCGAATACAGCAACACCGTCAAGCCGATCCGCG
CGCTCAGCCAGGTGCGCGCGTCCATCCTCGAGGTGCAACGTTACATCCGCAGCATGCAGGCGAGCCACGACGCCGAGCGC
AACGCGCACTCGCGCGAGCTCATCGCGCAGTCGCTCGACAAGATCGACAAGGCCTGGCCGGTGTACTACCCGTCCGGCGT
CTCCTCGGACGCGGAGCGCGCGATCGCCGATCGGATCAACACGGCGCTGCCGCAGTTTCGCGACTCGAGCGCACAAATCG
TGGCGGCGCTCGCGGCCGGTAACAACGACATGGTGAACCAACTCGCCGACGCGCAGCGCGCCGTGGCGGACCCGACGCTC
GACGCGATCGCCACCGACATCGACATGAACGACAAGCAGGCCGCGCAGTACGCGGCAGACGGAGCGGCCAGCGCGCAGAA
GGCGCGCTACACCGCCGTCGCGCTGATGGTCCTCGGCGTGGCGCTGGCTGTCGGCGCGTCGCTCTATCTGCTGCGCATCA
TCATGCGGCCGCTGAACGCGGCGATCGGCGTGGCCAATACGATCGCCGACGGGCAGCTCGAAGTGGCAATCGACACCTCG
CATCGCGGCGAATTCGGCCAGCTGATGCAAGCGCTGCAGATCATGGACACGCAGCTCGCGCAGACGGTGCATCGCATCCA
GGGCAGCACCGGCTCGGTATCGCTCGCGGCCAAGGAGATCGCGACCGGCAATCTCGATCTGTCGTCGCGCACCGAGCAGC
AGGCCGCCTCGCTCGAGGAAACCGCCACGAGCATGACGCAGCTGACCGAGACGGTGAAGCAGAACGCCGACAATGCGCGG
CAGGCCAACGGCCTCGCCACCCAGGCATCGAGCCTCGCCGAGGACAACAACCAGGCGATGCGCGAGATGGTCGACACCAT
CATGCGGATCAGCGGCAGCTCGGGGAAGATTTCCGAGATCACCGGCACCATCGAGGGCATCGCGTTCCAGACCAACATCC
TGGCGCTGAACGCGGCCGTGGAAGCCGCGCGCGCGGGCGAACAGGGCCGCGGCTTCGCGGTGGTGGCGAGCGAGGTGCGC
ACGCTGGCGCAGCGCTCGGCGGCGGCGGCCAAGGAGATCAAGGAACTGATTGCCTCGTCGGTCGTGCTGATCGAGGGCGG
CGCGGGGCAGGCCAACGACGTCAGCAACAAGATGAGCCACGTGCGCGAAGCGATCCGCCGCGTGTCGGACATCGTCGCGG
AAATCTCGGCCGCCTCCGACGAACAGTCGCGCGGCATCGAGCAGATCAACCAAGCCGTCTCGCAGATGGATACCGTCACG
CAGCAGAACGCGGCGCTGGTGGAGCAGTCCGCGGCGGCGGCGCAATCGCTGGACGAGCAGTCGTCGCTGCTGGCGCAGGC
GGTGGCCGTGTTCCGCCTGACGGGCCACACCGGCACGCGCCACGCGTCGGCCGCGCGGCACCCCGTGGCGGCCGCGCCGT
TCGCGGCAGGACCGGCTGGCCTTTGA

Upstream 100 bases:

>100_bases
GTCCGTATTCTGCGGCCGCGAACAGCCCTGCATGGCCGACGCCCTTGCGACGCGCCGCAATCCGCCCGCCTCCGCGCGGG
CTTCCCCGGAGAGTTCCATC

Downstream 100 bases:

>100_bases
TGGTTGCAATGGGTCGCGCGGCGGCGGTTGGTGGCTGCCGCGGCTGCCGTAACAGGCCGCTTCGAAAAACCCGCTCGGCA
CGCCCGCGGACGTGCCAACA

Product: putative methyl-accepting chemotaxis transducer transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNHLHQTVRFKIVAAMTACVLVIAFIGVYGSLTIARLEHIVRSEYSNTVKPIRALSQVRASILEVQRYIRSMQASHDAER
NAHSRELIAQSLDKIDKAWPVYYPSGVSSDAERAIADRINTALPQFRDSSAQIVAALAAGNNDMVNQLADAQRAVADPTL
DAIATDIDMNDKQAAQYAADGAASAQKARYTAVALMVLGVALAVGASLYLLRIIMRPLNAAIGVANTIADGQLEVAIDTS
HRGEFGQLMQALQIMDTQLAQTVHRIQGSTGSVSLAAKEIATGNLDLSSRTEQQAASLEETATSMTQLTETVKQNADNAR
QANGLATQASSLAEDNNQAMREMVDTIMRISGSSGKISEITGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVR
TLAQRSAAAAKEIKELIASSVVLIEGGAGQANDVSNKMSHVREAIRRVSDIVAEISAASDEQSRGIEQINQAVSQMDTVT
QQNAALVEQSAAAAQSLDEQSSLLAQAVAVFRLTGHTGTRHASAARHPVAAAPFAAGPAGL

Sequences:

>Translated_541_residues
MNHLHQTVRFKIVAAMTACVLVIAFIGVYGSLTIARLEHIVRSEYSNTVKPIRALSQVRASILEVQRYIRSMQASHDAER
NAHSRELIAQSLDKIDKAWPVYYPSGVSSDAERAIADRINTALPQFRDSSAQIVAALAAGNNDMVNQLADAQRAVADPTL
DAIATDIDMNDKQAAQYAADGAASAQKARYTAVALMVLGVALAVGASLYLLRIIMRPLNAAIGVANTIADGQLEVAIDTS
HRGEFGQLMQALQIMDTQLAQTVHRIQGSTGSVSLAAKEIATGNLDLSSRTEQQAASLEETATSMTQLTETVKQNADNAR
QANGLATQASSLAEDNNQAMREMVDTIMRISGSSGKISEITGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVR
TLAQRSAAAAKEIKELIASSVVLIEGGAGQANDVSNKMSHVREAIRRVSDIVAEISAASDEQSRGIEQINQAVSQMDTVT
QQNAALVEQSAAAAQSLDEQSSLLAQAVAVFRLTGHTGTRHASAARHPVAAAPFAAGPAGL
>Mature_541_residues
MNHLHQTVRFKIVAAMTACVLVIAFIGVYGSLTIARLEHIVRSEYSNTVKPIRALSQVRASILEVQRYIRSMQASHDAER
NAHSRELIAQSLDKIDKAWPVYYPSGVSSDAERAIADRINTALPQFRDSSAQIVAALAAGNNDMVNQLADAQRAVADPTL
DAIATDIDMNDKQAAQYAADGAASAQKARYTAVALMVLGVALAVGASLYLLRIIMRPLNAAIGVANTIADGQLEVAIDTS
HRGEFGQLMQALQIMDTQLAQTVHRIQGSTGSVSLAAKEIATGNLDLSSRTEQQAASLEETATSMTQLTETVKQNADNAR
QANGLATQASSLAEDNNQAMREMVDTIMRISGSSGKISEITGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVR
TLAQRSAAAAKEIKELIASSVVLIEGGAGQANDVSNKMSHVREAIRRVSDIVAEISAASDEQSRGIEQINQAVSQMDTVT
QQNAALVEQSAAAAQSLDEQSSLLAQAVAVFRLTGHTGTRHASAARHPVAAAPFAAGPAGL

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=466, Percent_Identity=43.5622317596566, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI2367378, Length=522, Percent_Identity=41.5708812260536, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1788194, Length=385, Percent_Identity=47.7922077922078, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788195, Length=324, Percent_Identity=52.1604938271605, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1789453, Length=322, Percent_Identity=34.7826086956522, Blast_Score=171, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57070; Mature: 57070

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLHQTVRFKIVAAMTACVLVIAFIGVYGSLTIARLEHIVRSEYSNTVKPIRALSQVRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILEVQRYIRSMQASHDAERNAHSRELIAQSLDKIDKAWPVYYPSGVSSDAERAIADRIN
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
TALPQFRDSSAQIVAALAAGNNDMVNQLADAQRAVADPTLDAIATDIDMNDKQAAQYAAD
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHC
GAASAQKARYTAVALMVLGVALAVGASLYLLRIIMRPLNAAIGVANTIADGQLEVAIDTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
HRGEFGQLMQALQIMDTQLAQTVHRIQGSTGSVSLAAKEIATGNLDLSSRTEQQAASLEE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHHH
TATSMTQLTETVKQNADNARQANGLATQASSLAEDNNQAMREMVDTIMRISGSSGKISEI
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHH
TGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAAAAKEIKELIASS
HHHHHHHEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VVLIEGGAGQANDVSNKMSHVREAIRRVSDIVAEISAASDEQSRGIEQINQAVSQMDTVT
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHH
QQNAALVEQSAAAAQSLDEQSSLLAQAVAVFRLTGHTGTRHASAARHPVAAAPFAAGPAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCC
L
C
>Mature Secondary Structure
MNHLHQTVRFKIVAAMTACVLVIAFIGVYGSLTIARLEHIVRSEYSNTVKPIRALSQVRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILEVQRYIRSMQASHDAERNAHSRELIAQSLDKIDKAWPVYYPSGVSSDAERAIADRIN
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
TALPQFRDSSAQIVAALAAGNNDMVNQLADAQRAVADPTLDAIATDIDMNDKQAAQYAAD
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHC
GAASAQKARYTAVALMVLGVALAVGASLYLLRIIMRPLNAAIGVANTIADGQLEVAIDTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
HRGEFGQLMQALQIMDTQLAQTVHRIQGSTGSVSLAAKEIATGNLDLSSRTEQQAASLEE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHHH
TATSMTQLTETVKQNADNARQANGLATQASSLAEDNNQAMREMVDTIMRISGSSGKISEI
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHH
TGTIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAAAAKEIKELIASS
HHHHHHHEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VVLIEGGAGQANDVSNKMSHVREAIRRVSDIVAEISAASDEQSRGIEQINQAVSQMDTVT
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHH
QQNAALVEQSAAAAQSLDEQSSLLAQAVAVFRLTGHTGTRHASAARHPVAAAPFAAGPAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]