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The map label for this gene is pcaI [H]

Identifier: 238023560

GI number: 238023560

Start: 64892

End: 65593

Strand: Direct

Name: pcaI [H]

Synonym: bglu_2g00620

Alternate gene names: 238023560

Gene position: 64892-65593 (Clockwise)

Preceding gene: 238023559

Following gene: 238023561

Centisome position: 2.3

GC content: 67.38

Gene sequence:

>702_bases
ATGGTCAACAAGATTTTCGATTCCCTGCAGTCGGCGGTGGCCGACATCCATGACGGCGCGACCGTCATGATCGGCGGCTT
CGGCACGGCGGGCATGCCGTCCGAGCTGATCGACGCGCTGATCGCGCATGGCGCGCGCGATCTGACGATCGTCAACAACA
ACGCCGGCAACGGCGAAACCGGCCTGGCCGCGCTGCTGAAGGCCAGGCGCGTGCGCAAGATCATCTGCTCGTTCCCGCGC
CAGTCCGATTCGCAGGTGTTCGACGCGCTCTACCGCGGCGGCGAGATCGAGCTGGAGCTGGTGCCGCAAGGCAATCTCGC
CGAGCGCATCCGCGCGGCCGGCGCCGGCATCGGCGGGTTCTTCACGCGCACCGGCTACGGCACGAAGCTGGCCGAAGGCA
AGGAAACGCGCGAGATCGACGGCAAGCACTACGTGTTCGAGACGCCGATCCACGCCGATTTCGCGCTGGTGAAGGCGTTC
AAGGGCGACCGGTGGGGCAACCTGGTCTATCGCAAGACCGCGCGCAACTTCGGGCCGGTGATGGCGAGCGCGGCGAAGAC
CACGATCGTGCAGGTCTCGCAGGTTGTCGAGCTTGGCGGGCTCGATCCCGAACAGATCGTGACGCCCGGCATCTTCGTGC
AGCGCGTCGTCGAGGTGCCGCAGGCCGTCCATGCGGCCGAACTCGCCGCGCAGGCCGCCTGA

Upstream 100 bases:

>100_bases
CAAATGGGCTGCCCGGTGGCCCGATGCGGCGTGGCCCGAGTGAATCCGGCGCGCTGGCCGGCCGTCGCGCTGCGCGACGC
GGATTCCCTCAGGAAGAGTC

Downstream 100 bases:

>100_bases
ACCCGGAGAACCCACGATGAAACGACTGACCCGTGATGAGATGGCCCAGCGCGTGGCCCGCGACATTCCCGAAGGCGCCT
ACGTGAACCTCGGCATCGGC

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVNKIFDSLQSAVADIHDGATVMIGGFGTAGMPSELIDALIAHGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPR
QSDSQVFDALYRGGEIELELVPQGNLAERIRAAGAGIGGFFTRTGYGTKLAEGKETREIDGKHYVFETPIHADFALVKAF
KGDRWGNLVYRKTARNFGPVMASAAKTTIVQVSQVVELGGLDPEQIVTPGIFVQRVVEVPQAVHAAELAAQAA

Sequences:

>Translated_233_residues
MVNKIFDSLQSAVADIHDGATVMIGGFGTAGMPSELIDALIAHGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPR
QSDSQVFDALYRGGEIELELVPQGNLAERIRAAGAGIGGFFTRTGYGTKLAEGKETREIDGKHYVFETPIHADFALVKAF
KGDRWGNLVYRKTARNFGPVMASAAKTTIVQVSQVVELGGLDPEQIVTPGIFVQRVVEVPQAVHAAELAAQAA
>Mature_233_residues
MVNKIFDSLQSAVADIHDGATVMIGGFGTAGMPSELIDALIAHGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPR
QSDSQVFDALYRGGEIELELVPQGNLAERIRAAGAGIGGFFTRTGYGTKLAEGKETREIDGKHYVFETPIHADFALVKAF
KGDRWGNLVYRKTARNFGPVMASAAKTTIVQVSQVVELGGLDPEQIVTPGIFVQRVVEVPQAVHAAELAAQAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=233, Percent_Identity=44.6351931330472, Blast_Score=207, Evalue=6e-54,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=46.3519313304721, Blast_Score=194, Evalue=5e-50,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=43.4579439252336, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=43.0379746835443, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=44.1558441558442, Blast_Score=193, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=44.1558441558442, Blast_Score=193, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24817; Mature: 24817

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKIFDSLQSAVADIHDGATVMIGGFGTAGMPSELIDALIAHGARDLTIVNNNAGNGET
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKARRVRKIICSFPRQSDSQVFDALYRGGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCHH
FTRTGYGTKLAEGKETREIDGKHYVFETPIHADFALVKAFKGDRWGNLVYRKTARNFGPV
HHCCCCCCCCCCCCCHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
MASAAKTTIVQVSQVVELGGLDPEQIVTPGIFVQRVVEVPQAVHAAELAAQAA
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNKIFDSLQSAVADIHDGATVMIGGFGTAGMPSELIDALIAHGARDLTIVNNNAGNGET
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKARRVRKIICSFPRQSDSQVFDALYRGGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCHH
FTRTGYGTKLAEGKETREIDGKHYVFETPIHADFALVKAFKGDRWGNLVYRKTARNFGPV
HHCCCCCCCCCCCCCHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
MASAAKTTIVQVSQVVELGGLDPEQIVTPGIFVQRVVEVPQAVHAAELAAQAA
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]