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The map label for this gene is atoC [H]

Identifier: 238023537

GI number: 238023537

Start: 42706

End: 44088

Strand: Direct

Name: atoC [H]

Synonym: bglu_2g00380

Alternate gene names: 238023537

Gene position: 42706-44088 (Clockwise)

Preceding gene: 238023533

Following gene: 238023541

Centisome position: 1.51

GC content: 69.49

Gene sequence:

>1383_bases
ATGCCACGCATTTTGATCGTCGATGACGATAGCGACACGCGCGAGATGCTGGTCGCGCTGGCGCAGCAGCGGCAACTGAC
CTGCGATACCGCCGCCTCGCTGGCCGAGGCCCGCTCGCGCATGCTGACCCAGACCTACGAGCTGGTGCTCTGCGACCTGG
TGCTGCCCGACGGCAACGGCATCGAGCTGTTCGAGGACTTCACGCAGCGCGGCAAACGCGGCGAGCTGGTGTTCGCCACC
GGCCACGCCACCCTCGACACCGCGATCGACGCGTTGCGGCAGGGCGCGAGCGACTATCTCGTCAAGCCGTTCAACATGCA
GCGGCTGGACGGCATCTTCGCGCGCGTCGCGCAGATGGAGGTCCACGAGGAGGAGATCGGCGCGATGCGCGACGAACTCG
AGCGCGCCGGCCGCTTCGGCCGCCTGCTCGGCCACTCGCCGCCGATGCGCACGATGTACGACGCGCTCGCGCGGGTGGCC
ACCACCGACGCCTCGGTGCTGCTGACGGGCGAATCGGGCACCGGCAAGGAAGTGGCCGCGCAGACGCTGCACGAGCTGAG
CTTCCGGCGGCGCGGGCCGTTCGTGGCGATCAACTGCGGCGCGATCCCGGCCAACCTGGTCGAAAGCGAGATGTTCGGCC
ACGACCGCGGCAGCTTCACGGGCGCGGACCGCCAGCACAAGGGCTTCTTCGAGCGCGCCGACGGCGGCACGCTGTTCCTC
GACGAGATCACCGAGATGCCGGTCGAGCTGCAGGTCAAGCTGCTGCGCGTGCTCGAGACGGGGCAGGTCACGCGGCTCGG
CTCGGTGCGCGAGACCTCGATCGACGTGCGCATCATCGCCGCCACCAATCGCGACCCGGAGGCCGCGATCGCGGCCGGCA
CGCTGCGCGCGGATCTCTATCACCGCATCAACGTGTTTCCGATTCCGATGCCGCCGCTGCGCGAACGCGGCACGGACATC
GTGCTGCTGGCCGATGCGTTCCTCGCGCGGCTCAACGAGCACAGCGGCCGCGCGATGCGCTTTAGCGACGCCGCGAAGGC
CGCCCTGATGCGCTACGACTGGCCCGGCAACGTGCGCGAGCTGCGCAACTTCGTGCAGCGCGCGAGCATCTTCGCCGACG
GCGACGCGATCGACACGCTGCCGCCGCCGATCATGGACGAGGTGTCAGGCATGGCCAGCACCGGCGCCAATGCCGTGACG
GTGCCGCTCGACATGCCGCTCGAGGAAGTCGACCGCCGGCTGATCCTCGGCACCCTCGAGCAGTGCGGCGGCGTGAAGGC
GCACGCGGCCGAGATTCTCGACATCAGCCTGAAGACGGTCTACAACCGCATCGGTGCGCCGGGCGAGAAGGCCGCGGGCG
ACAAGCCGCGCGACGAGAAATGA

Upstream 100 bases:

>100_bases
GCGCCGCACCCCGCATCGATGACTCCGTCCAACTCTCTCATCTTCGCCGCCGCCGATGTGGCATCAGGGGCGCGCGATGC
AATCGTTCAAAGGAGTTCGC

Downstream 100 bases:

>100_bases
GCGGGCCGCGCGGCGCACGCGGCCGGTGCCGGCCGCGCCGTCGCGCCGGCTTCGGTGCCGGCTTTCAGCGCGACACGGCG
ATCGCCGCGTTGACGGGCAC

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MPRILIVDDDSDTREMLVALAQQRQLTCDTAASLAEARSRMLTQTYELVLCDLVLPDGNGIELFEDFTQRGKRGELVFAT
GHATLDTAIDALRQGASDYLVKPFNMQRLDGIFARVAQMEVHEEEIGAMRDELERAGRFGRLLGHSPPMRTMYDALARVA
TTDASVLLTGESGTGKEVAAQTLHELSFRRRGPFVAINCGAIPANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFL
DEITEMPVELQVKLLRVLETGQVTRLGSVRETSIDVRIIAATNRDPEAAIAAGTLRADLYHRINVFPIPMPPLRERGTDI
VLLADAFLARLNEHSGRAMRFSDAAKAALMRYDWPGNVRELRNFVQRASIFADGDAIDTLPPPIMDEVSGMASTGANAVT
VPLDMPLEEVDRRLILGTLEQCGGVKAHAAEILDISLKTVYNRIGAPGEKAAGDKPRDEK

Sequences:

>Translated_460_residues
MPRILIVDDDSDTREMLVALAQQRQLTCDTAASLAEARSRMLTQTYELVLCDLVLPDGNGIELFEDFTQRGKRGELVFAT
GHATLDTAIDALRQGASDYLVKPFNMQRLDGIFARVAQMEVHEEEIGAMRDELERAGRFGRLLGHSPPMRTMYDALARVA
TTDASVLLTGESGTGKEVAAQTLHELSFRRRGPFVAINCGAIPANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFL
DEITEMPVELQVKLLRVLETGQVTRLGSVRETSIDVRIIAATNRDPEAAIAAGTLRADLYHRINVFPIPMPPLRERGTDI
VLLADAFLARLNEHSGRAMRFSDAAKAALMRYDWPGNVRELRNFVQRASIFADGDAIDTLPPPIMDEVSGMASTGANAVT
VPLDMPLEEVDRRLILGTLEQCGGVKAHAAEILDISLKTVYNRIGAPGEKAAGDKPRDEK
>Mature_459_residues
PRILIVDDDSDTREMLVALAQQRQLTCDTAASLAEARSRMLTQTYELVLCDLVLPDGNGIELFEDFTQRGKRGELVFATG
HATLDTAIDALRQGASDYLVKPFNMQRLDGIFARVAQMEVHEEEIGAMRDELERAGRFGRLLGHSPPMRTMYDALARVAT
TDASVLLTGESGTGKEVAAQTLHELSFRRRGPFVAINCGAIPANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFLD
EITEMPVELQVKLLRVLETGQVTRLGSVRETSIDVRIIAATNRDPEAAIAAGTLRADLYHRINVFPIPMPPLRERGTDIV
LLADAFLARLNEHSGRAMRFSDAAKAALMRYDWPGNVRELRNFVQRASIFADGDAIDTLPPPIMDEVSGMASTGANAVTV
PLDMPLEEVDRRLILGTLEQCGGVKAHAAEILDISLKTVYNRIGAPGEKAAGDKPRDEK

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=450, Percent_Identity=38, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=39.5089285714286, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI1790299, Length=375, Percent_Identity=40.8, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI87082117, Length=315, Percent_Identity=42.8571428571429, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788905, Length=395, Percent_Identity=38.9873417721519, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789087, Length=318, Percent_Identity=43.0817610062893, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI87082152, Length=234, Percent_Identity=48.2905982905983, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=344, Percent_Identity=38.953488372093, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789233, Length=315, Percent_Identity=40, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=306, Percent_Identity=39.8692810457516, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787583, Length=270, Percent_Identity=38.1481481481481, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1789828, Length=309, Percent_Identity=31.7152103559871, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87081858, Length=321, Percent_Identity=29.9065420560748, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786838, Length=117, Percent_Identity=31.6239316239316, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790552, Length=107, Percent_Identity=34.5794392523364, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50455; Mature: 50324

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRILIVDDDSDTREMLVALAQQRQLTCDTAASLAEARSRMLTQTYELVLCDLVLPDGNG
CCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
IELFEDFTQRGKRGELVFATGHATLDTAIDALRQGASDYLVKPFNMQRLDGIFARVAQME
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHHHHH
VHEEEIGAMRDELERAGRFGRLLGHSPPMRTMYDALARVATTDASVLLTGESGTGKEVAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
QTLHELSFRRRGPFVAINCGAIPANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFL
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCEEEH
DEITEMPVELQVKLLRVLETGQVTRLGSVRETSIDVRIIAATNRDPEAAIAAGTLRADLY
HHHHCCCHHHHHHHHHHHHCCCEEECCCCEECCEEEEEEEECCCCCCHHHHHHHHHHHHH
HRINVFPIPMPPLRERGTDIVLLADAFLARLNEHSGRAMRFSDAAKAALMRYDWPGNVRE
HHCEEEECCCCCHHHCCCCEEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCHHH
LRNFVQRASIFADGDAIDTLPPPIMDEVSGMASTGANAVTVPLDMPLEEVDRRLILGTLE
HHHHHHHHHHEECCCCCCCCCCCHHHHHCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
QCGGVKAHAAEILDISLKTVYNRIGAPGEKAAGDKPRDEK
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRILIVDDDSDTREMLVALAQQRQLTCDTAASLAEARSRMLTQTYELVLCDLVLPDGNG
CEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
IELFEDFTQRGKRGELVFATGHATLDTAIDALRQGASDYLVKPFNMQRLDGIFARVAQME
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHHHHH
VHEEEIGAMRDELERAGRFGRLLGHSPPMRTMYDALARVATTDASVLLTGESGTGKEVAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
QTLHELSFRRRGPFVAINCGAIPANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFL
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCEEEH
DEITEMPVELQVKLLRVLETGQVTRLGSVRETSIDVRIIAATNRDPEAAIAAGTLRADLY
HHHHCCCHHHHHHHHHHHHCCCEEECCCCEECCEEEEEEEECCCCCCHHHHHHHHHHHHH
HRINVFPIPMPPLRERGTDIVLLADAFLARLNEHSGRAMRFSDAAKAALMRYDWPGNVRE
HHCEEEECCCCCHHHCCCCEEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCHHH
LRNFVQRASIFADGDAIDTLPPPIMDEVSGMASTGANAVTVPLDMPLEEVDRRLILGTLE
HHHHHHHHHHEECCCCCCCCCCCHHHHHCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
QCGGVKAHAAEILDISLKTVYNRIGAPGEKAAGDKPRDEK
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]