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The map label for this gene is gudD [H]

Identifier: 238023518

GI number: 238023518

Start: 18735

End: 20084

Strand: Direct

Name: gudD [H]

Synonym: bglu_2g00180

Alternate gene names: 238023518

Gene position: 18735-20084 (Clockwise)

Preceding gene: 238023516

Following gene: 238023519

Centisome position: 0.66

GC content: 69.85

Gene sequence:

>1350_bases
ATGACCTCGAACTCCGTCCAGGCGAACGCCACCCCCGTCGTGAACGAGCTGCGCGTCGTGCCGGTGGCCGGCCGCGACAG
CATGCTGATGAACCTGAGCGGCGCGCATGGCCCGTTCTTCACGCGCAACATCGTGATCCTGCGCGACAGCAGCGGCCACA
CCGGCATCGGCGAAGTGCCGGGCGGCGAGGCGATTCGCAAGACCATCGACGACGCGCGCGAGATCGTGGTGGGCCAGTCG
ATCGGCAACCTGCAGGCGGTGCTGAACCGCGTGCGCTCGCAGTTCGCCGATCGCGACGCCGGCGGCCGCGGCCTGCAGAC
CTTCGACCTGCGCACCACGATCCATGCCGTCACCGCGCTCGAGGCGGCGCTGCTGGACCTGCTCGGCCAGCACCTGAACG
TGCCGGTCGCGGCGCTGCTCGGCGAAGGCCAGCAACGCGACGAGGTGGAGATGCTCGGCTACCTGTTCTACATCGGCGAC
CGCAACCGGACCGACCTGCCCTACGCGAGCGGTGCCGATGGCCGCGACGACTGGGAGCGGCTGCGCACCGAGGAGGCGAT
GACGCCGGAGGCGGTGGTGCGGCTGGCCGAGGCCGCGCAGGCGCGCTACGGCTTCAACGACTTCAAGCTCAAGGGCGGCG
TGCTGGCCGGCGACGCGGAGATCGAGGCGGCCCGTGCGCTGGCCGAGCGGTTCCCGAACGCGCGCGTGACGCTCGACCCG
AACGGTGCCTGGTCGCTGGCCGAGGCGGTGCGCCTGTGCCGCGACATGCATGGCGTGCTCGCCTACGCGGAAGACCCGTG
CGGTGCCGAGAACGGCTATTCGGGCCGCGAGGTGATGGCCGAGTTCCGCCGCGCCACCGGCCTGCCGACGGCCACCAACA
TGATCGCCACCGACTGGCGCCAGATGGGCCACGCGATCCAGCTGCAATCGGTGGACATTCCGCTTGCCGATCCGCACTTC
TGGACCATGCAGGGCTCGGTGCGCGTCGCGCAGATGTGCAACGACTGGGGCCTGACCTGGGGCTCGCACTCGAACAATCA
CTTCGACGTCTCGCTGGCGATGTTCACCCACGTGGCCGCGGCCGCGCCGGGCAGGATCACCGCGATCGACACCCACTGGA
TCTGGCAGGACGGCCAGTTCCTGACGCAGAACCCGCTGCAGATCGTCGGCGGCAAGGTGAAGGTGCCCGCCAAGCCGGGC
CTCGGCATCGAGCCCGACATGGATGCGCTGGAGCGCGCCCATGCGCTGTACGAGCAGCACGGCCTGGGCGCGCGCGACGA
CGGCATCGCCATGCAGTACCTGATCCCGAACTGGAAGTTCGACAACAAGCGTCCGTGCCTCGTGCGCTGA

Upstream 100 bases:

>100_bases
GGCCGCGTGGAACGCCCGCCCCGGCCGGGCGGCGCCCGCGTGGCGCTGCCGTTTTCCTTCACCCCGGCGCTGATCGCAGC
GCCTTTTCCAGGTAATGCAC

Downstream 100 bases:

>100_bases
TCAGCGCGCCGGCCGCCGCCGCCTCGAACTCCGCAAGCGGTCGAAACCGCCCCTCATCCAACCGACTCCGCATCCGGCAA
CGCCATGACCACGCCTCAGG

Product: Mandelate racemase/muconate lactonizing enzyme-like protein

Products: NA

Alternate protein names: GDH; GlucD [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTSNSVQANATPVVNELRVVPVAGRDSMLMNLSGAHGPFFTRNIVILRDSSGHTGIGEVPGGEAIRKTIDDAREIVVGQS
IGNLQAVLNRVRSQFADRDAGGRGLQTFDLRTTIHAVTALEAALLDLLGQHLNVPVAALLGEGQQRDEVEMLGYLFYIGD
RNRTDLPYASGADGRDDWERLRTEEAMTPEAVVRLAEAAQARYGFNDFKLKGGVLAGDAEIEAARALAERFPNARVTLDP
NGAWSLAEAVRLCRDMHGVLAYAEDPCGAENGYSGREVMAEFRRATGLPTATNMIATDWRQMGHAIQLQSVDIPLADPHF
WTMQGSVRVAQMCNDWGLTWGSHSNNHFDVSLAMFTHVAAAAPGRITAIDTHWIWQDGQFLTQNPLQIVGGKVKVPAKPG
LGIEPDMDALERAHALYEQHGLGARDDGIAMQYLIPNWKFDNKRPCLVR

Sequences:

>Translated_449_residues
MTSNSVQANATPVVNELRVVPVAGRDSMLMNLSGAHGPFFTRNIVILRDSSGHTGIGEVPGGEAIRKTIDDAREIVVGQS
IGNLQAVLNRVRSQFADRDAGGRGLQTFDLRTTIHAVTALEAALLDLLGQHLNVPVAALLGEGQQRDEVEMLGYLFYIGD
RNRTDLPYASGADGRDDWERLRTEEAMTPEAVVRLAEAAQARYGFNDFKLKGGVLAGDAEIEAARALAERFPNARVTLDP
NGAWSLAEAVRLCRDMHGVLAYAEDPCGAENGYSGREVMAEFRRATGLPTATNMIATDWRQMGHAIQLQSVDIPLADPHF
WTMQGSVRVAQMCNDWGLTWGSHSNNHFDVSLAMFTHVAAAAPGRITAIDTHWIWQDGQFLTQNPLQIVGGKVKVPAKPG
LGIEPDMDALERAHALYEQHGLGARDDGIAMQYLIPNWKFDNKRPCLVR
>Mature_448_residues
TSNSVQANATPVVNELRVVPVAGRDSMLMNLSGAHGPFFTRNIVILRDSSGHTGIGEVPGGEAIRKTIDDAREIVVGQSI
GNLQAVLNRVRSQFADRDAGGRGLQTFDLRTTIHAVTALEAALLDLLGQHLNVPVAALLGEGQQRDEVEMLGYLFYIGDR
NRTDLPYASGADGRDDWERLRTEEAMTPEAVVRLAEAAQARYGFNDFKLKGGVLAGDAEIEAARALAERFPNARVTLDPN
GAWSLAEAVRLCRDMHGVLAYAEDPCGAENGYSGREVMAEFRRATGLPTATNMIATDWRQMGHAIQLQSVDIPLADPHFW
TMQGSVRVAQMCNDWGLTWGSHSNNHFDVSLAMFTHVAAAAPGRITAIDTHWIWQDGQFLTQNPLQIVGGKVKVPAKPGL
GIEPDMDALERAHALYEQHGLGARDDGIAMQYLIPNWKFDNKRPCLVR

Specific function: Catalyzes the dehydration of glucarate to 5-keto-4- deoxy-D-glucarate (5-kdGluc). Also acts on L-idarate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789150, Length=440, Percent_Identity=75, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI1789151, Length=443, Percent_Identity=63.2054176072235, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017653
- InterPro:   IPR013342
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.40 [H]

Molecular weight: Translated: 49038; Mature: 48907

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNSVQANATPVVNELRVVPVAGRDSMLMNLSGAHGPFFTRNIVILRDSSGHTGIGEVP
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCC
GGEAIRKTIDDAREIVVGQSIGNLQAVLNRVRSQFADRDAGGRGLQTFDLRTTIHAVTAL
CHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHH
EAALLDLLGQHLNVPVAALLGEGQQRDEVEMLGYLFYIGDRNRTDLPYASGADGRDDWER
HHHHHHHHHHHCCCCHHHHHCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCCCCHHHHHH
LRTEEAMTPEAVVRLAEAAQARYGFNDFKLKGGVLAGDAEIEAARALAERFPNARVTLDP
HHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCEEECCHHHHHHHHHHHHCCCCEEEECC
NGAWSLAEAVRLCRDMHGVLAYAEDPCGAENGYSGREVMAEFRRATGLPTATNMIATDWR
CCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QMGHAIQLQSVDIPLADPHFWTMQGSVRVAQMCNDWGLTWGSHSNNHFDVSLAMFTHVAA
HCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHH
AAPGRITAIDTHWIWQDGQFLTQNPLQIVGGKVKVPAKPGLGIEPDMDALERAHALYEQH
CCCCCEEEEEEEEEEECCCEECCCCHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
GLGARDDGIAMQYLIPNWKFDNKRPCLVR
CCCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSNSVQANATPVVNELRVVPVAGRDSMLMNLSGAHGPFFTRNIVILRDSSGHTGIGEVP
CCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCC
GGEAIRKTIDDAREIVVGQSIGNLQAVLNRVRSQFADRDAGGRGLQTFDLRTTIHAVTAL
CHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHH
EAALLDLLGQHLNVPVAALLGEGQQRDEVEMLGYLFYIGDRNRTDLPYASGADGRDDWER
HHHHHHHHHHHCCCCHHHHHCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCCCCHHHHHH
LRTEEAMTPEAVVRLAEAAQARYGFNDFKLKGGVLAGDAEIEAARALAERFPNARVTLDP
HHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCEEECCHHHHHHHHHHHHCCCCEEEECC
NGAWSLAEAVRLCRDMHGVLAYAEDPCGAENGYSGREVMAEFRRATGLPTATNMIATDWR
CCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QMGHAIQLQSVDIPLADPHFWTMQGSVRVAQMCNDWGLTWGSHSNNHFDVSLAMFTHVAA
HCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHH
AAPGRITAIDTHWIWQDGQFLTQNPLQIVGGKVKVPAKPGLGIEPDMDALERAHALYEQH
CCCCCEEEEEEEEEEECCCEECCCCHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
GLGARDDGIAMQYLIPNWKFDNKRPCLVR
CCCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]