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The map label for this gene is uxuR [H]

Identifier: 238023517

GI number: 238023517

Start: 17421

End: 18131

Strand: Reverse

Name: uxuR [H]

Synonym: bglu_2g00170

Alternate gene names: 238023517

Gene position: 18131-17421 (Counterclockwise)

Preceding gene: 238023520

Following gene: 238023515

Centisome position: 0.64

GC content: 69.62

Gene sequence:

>711_bases
ATGAGCAGCCTGTCCGAGAAGGTCGTCGCGTCCCTGTCCGAAGAAATCCGCCGCGGCACGCTGCGCCCCGGCGACCGGCT
GCCCACCGAGGTCGCGATGATGAAGCAGCTGTCGGTCAGCCGCTCGGTGATCCGCGAGGCGATCTCGCGCCTGCAGGCCG
CGCGCATCGTCGAGACGCGGCATGGCGTGGGCACCTTCGTGCTCGCGCCGCGCAACGATGCGACGATGCAGTTGCCCACC
GCCGACCTGTCGAACATGCTCGACGCGATGGCGGTGCTCGAATTCCGCATGGACGTGGAGGCCGCGTCGGCGGCGCTGGC
CGCGAAACGGCGCACCGAGTCGAACCTGCGGCAGATGCAGGCCGCGCTCGAGCGCTTCGAGGCCGAACTCGGGCGTGGCA
GCACCGATACGCTCGCGCACGACATCGAATTCCATCAGCAGATCGCCCAGGCGAGCGGCAACCGCTATTTCGTCGACGTG
CTGAGCCAGCTCGGCCATTCGGCCAGCCCGCGCACCCGGCTCGGCAGCGCCGAGCTGGCCGAACTCGACCAGATCGACCG
GCTGCGCCACGTGCTCGACGAGCACCGCTGGATCTATCGCGCGATCGAACGCCAGGACTCGGACGACGCGCGCGCGGCCA
TGCGCGTGCATCTCTCGAAGAGCCGCGAACGCCTGCAGCAGGCGCACGACACGAGCCATCCGCCCGCCTGA

Upstream 100 bases:

>100_bases
TCGAAACGTTTGCGGCTATGATGCCGCGTGCCGGGACATCGGATGACATCGCCGAGCCTCCCGCCGCCCAGCCCTCCGAT
TCCGCCCACCACCACCATCC

Downstream 100 bases:

>100_bases
GCAAGCGCGGCCGCGAACCGGGGCAGCCGGGCAGCCGCCCCTCGCCGCCGCGCCCAGCCGTGCGTTTCACGCGCGGGCGG
GTCTCCCGAAAACACTCACC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSSLSEKVVASLSEEIRRGTLRPGDRLPTEVAMMKQLSVSRSVIREAISRLQAARIVETRHGVGTFVLAPRNDATMQLPT
ADLSNMLDAMAVLEFRMDVEAASAALAAKRRTESNLRQMQAALERFEAELGRGSTDTLAHDIEFHQQIAQASGNRYFVDV
LSQLGHSASPRTRLGSAELAELDQIDRLRHVLDEHRWIYRAIERQDSDDARAAMRVHLSKSRERLQQAHDTSHPPA

Sequences:

>Translated_236_residues
MSSLSEKVVASLSEEIRRGTLRPGDRLPTEVAMMKQLSVSRSVIREAISRLQAARIVETRHGVGTFVLAPRNDATMQLPT
ADLSNMLDAMAVLEFRMDVEAASAALAAKRRTESNLRQMQAALERFEAELGRGSTDTLAHDIEFHQQIAQASGNRYFVDV
LSQLGHSASPRTRLGSAELAELDQIDRLRHVLDEHRWIYRAIERQDSDDARAAMRVHLSKSRERLQQAHDTSHPPA
>Mature_235_residues
SSLSEKVVASLSEEIRRGTLRPGDRLPTEVAMMKQLSVSRSVIREAISRLQAARIVETRHGVGTFVLAPRNDATMQLPTA
DLSNMLDAMAVLEFRMDVEAASAALAAKRRTESNLRQMQAALERFEAELGRGSTDTLAHDIEFHQQIAQASGNRYFVDVL
SQLGHSASPRTRLGSAELAELDQIDRLRHVLDEHRWIYRAIERQDSDDARAAMRVHLSKSRERLQQAHDTSHPPA

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=228, Percent_Identity=29.8245614035088, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI48994955, Length=236, Percent_Identity=30.5084745762712, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790032, Length=228, Percent_Identity=29.8245614035088, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87082208, Length=227, Percent_Identity=27.7533039647577, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786303, Length=128, Percent_Identity=35.9375, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26400; Mature: 26269

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLSEKVVASLSEEIRRGTLRPGDRLPTEVAMMKQLSVSRSVIREAISRLQAARIVETR
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGVGTFVLAPRNDATMQLPTADLSNMLDAMAVLEFRMDVEAASAALAAKRRTESNLRQMQ
CCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALERFEAELGRGSTDTLAHDIEFHQQIAQASGNRYFVDVLSQLGHSASPRTRLGSAELA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHH
ELDQIDRLRHVLDEHRWIYRAIERQDSDDARAAMRVHLSKSRERLQQAHDTSHPPA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSLSEKVVASLSEEIRRGTLRPGDRLPTEVAMMKQLSVSRSVIREAISRLQAARIVETR
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGVGTFVLAPRNDATMQLPTADLSNMLDAMAVLEFRMDVEAASAALAAKRRTESNLRQMQ
CCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALERFEAELGRGSTDTLAHDIEFHQQIAQASGNRYFVDVLSQLGHSASPRTRLGSAELA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHH
ELDQIDRLRHVLDEHRWIYRAIERQDSDDARAAMRVHLSKSRERLQQAHDTSHPPA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]