Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 237814187

GI number: 237814187

Start: 3821395

End: 3822339

Strand: Direct

Name: argC [H]

Synonym: GBP346_A3981

Alternate gene names: 237814187

Gene position: 3821395-3822339 (Clockwise)

Preceding gene: 237814186

Following gene: 237814188

Centisome position: 93.24

GC content: 68.15

Gene sequence:

>945_bases
ATGAGCACGAAAGTTTTTGTCGACGGCCAGGAAGGCACGACCGGTCTGAAGATCTTCGAATATCTGTTGGCGCGCAGCGA
CATCGACATCCTGCGCATCGACGAAGCGAAGCGCAAGGACGTCGACGAGCGCCGCCGCCTCATCAACGCGTCGGACGTGA
CGTTCCTGTGCCTGCCCGACGTCGCGTCGCGCGAATCGGCGACGCTCGTCGAGAACCCGAACACGACGCTGATCGACGCG
AGCACCGCGTTCCGCACGAGCGCCGACTGGGCATACGGCCTTCCCGAGCTGAACCGCGCGCAGCGCGAGCGCATCCGTGG
CGCGAAGCGCATCGCGGTGCCGGGGTGTCACGCGTCGGCGTTCGTGCTGGCGATGCGTCCGCTCGTCGACGCGGGCGTGG
TCGCGCCGGGCTTCGCCGCGCACAGCTATTCGATCACGGGCTACAGCGGCGGCGGCAAGAAGATGATCGCCGATTACGAA
GCGGGCGGCGCGAAGCTCGCGAGCCCGCGTCCGTATGCGCTCGGCCTCGCGCACAAGCATCTGCCGGAGATGGCCGCGCA
TACGGGCCTCACGAGCGCGCCGATCTTCACGCCGATCGTCGGGCCGTTCTACAAGGGCCTCGCCGTCACCACGTACTTCA
CGCCGGGCCAGCTCGCGAAGCGCGTGACGCCGCAGAACGTGCAGCGCGTGCTCGCCGAGCATTACGCGGGCGAGGCGTTC
GTGCGCGTCGCGCCGTACGACGCGGCCGAGAATCTCGACGATGGCTTCTTCGACGTGCAGGCGAACAACGACACGAACCG
CGTCGACCTGTTCGTGTTCGGCACGGCGGAACGCTTCGTCACCGTCGCGCGGCTCGACAACCTCGGCAAGGGCGCGTCGG
GCGCCGCGATCCAGTGCATGAATCTCAACGTCGGCGCGGCCGAGGGTACGGGGCTCGCGCGCTGA

Upstream 100 bases:

>100_bases
TTTTTTCGGCCGAACCGGTTACGGCGCCGCGCATCACGTCTTAAAATAATCGTTTTCCCGGCGGCCGCGCGCCGCCCCGC
CCCGATTCAGCGAGAGCGAG

Downstream 100 bases:

>100_bases
ACGCGCATTGCCTGCGGTGCGAGAGAAGCCGGCCCGAGCGCCGGCTTTTTTATTGCACCGAATGGAAATTGAAAGTTATT
TAAATATTGTCACGGCGCTA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSTKVFVDGQEGTTGLKIFEYLLARSDIDILRIDEAKRKDVDERRRLINASDVTFLCLPDVASRESATLVENPNTTLIDA
STAFRTSADWAYGLPELNRAQRERIRGAKRIAVPGCHASAFVLAMRPLVDAGVVAPGFAAHSYSITGYSGGGKKMIADYE
AGGAKLASPRPYALGLAHKHLPEMAAHTGLTSAPIFTPIVGPFYKGLAVTTYFTPGQLAKRVTPQNVQRVLAEHYAGEAF
VRVAPYDAAENLDDGFFDVQANNDTNRVDLFVFGTAERFVTVARLDNLGKGASGAAIQCMNLNVGAAEGTGLAR

Sequences:

>Translated_314_residues
MSTKVFVDGQEGTTGLKIFEYLLARSDIDILRIDEAKRKDVDERRRLINASDVTFLCLPDVASRESATLVENPNTTLIDA
STAFRTSADWAYGLPELNRAQRERIRGAKRIAVPGCHASAFVLAMRPLVDAGVVAPGFAAHSYSITGYSGGGKKMIADYE
AGGAKLASPRPYALGLAHKHLPEMAAHTGLTSAPIFTPIVGPFYKGLAVTTYFTPGQLAKRVTPQNVQRVLAEHYAGEAF
VRVAPYDAAENLDDGFFDVQANNDTNRVDLFVFGTAERFVTVARLDNLGKGASGAAIQCMNLNVGAAEGTGLAR
>Mature_313_residues
STKVFVDGQEGTTGLKIFEYLLARSDIDILRIDEAKRKDVDERRRLINASDVTFLCLPDVASRESATLVENPNTTLIDAS
TAFRTSADWAYGLPELNRAQRERIRGAKRIAVPGCHASAFVLAMRPLVDAGVVAPGFAAHSYSITGYSGGGKKMIADYEA
GGAKLASPRPYALGLAHKHLPEMAAHTGLTSAPIFTPIVGPFYKGLAVTTYFTPGQLAKRVTPQNVQRVLAEHYAGEAFV
RVAPYDAAENLDDGFFDVQANNDTNRVDLFVFGTAERFVTVARLDNLGKGASGAAIQCMNLNVGAAEGTGLAR

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=277, Percent_Identity=30.3249097472924, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320913, Length=316, Percent_Identity=27.5316455696203, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 33697; Mature: 33565

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKVFVDGQEGTTGLKIFEYLLARSDIDILRIDEAKRKDVDERRRLINASDVTFLCLPD
CCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHCCHHHHHHHCCCCCEEEEECCC
VASRESATLVENPNTTLIDASTAFRTSADWAYGLPELNRAQRERIRGAKRIAVPGCHASA
CCCCCCCEEEECCCCEEEECCHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHH
FVLAMRPLVDAGVVAPGFAAHSYSITGYSGGGKKMIADYEAGGAKLASPRPYALGLAHKH
HHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEECHHHHH
LPEMAAHTGLTSAPIFTPIVGPFYKGLAVTTYFTPGQLAKRVTPQNVQRVLAEHYAGEAF
HHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECCHHHHHCCCHHHHHHHHHHHCCCCEE
VRVAPYDAAENLDDGFFDVQANNDTNRVDLFVFGTAERFVTVARLDNLGKGASGAAIQCM
EEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEECHHHHEEHHHHHCCCCCCCCCEEEEE
NLNVGAAEGTGLAR
ECCCCCCCCCCCCC
>Mature Secondary Structure 
STKVFVDGQEGTTGLKIFEYLLARSDIDILRIDEAKRKDVDERRRLINASDVTFLCLPD
CCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHCCHHHHHHHCCCCCEEEEECCC
VASRESATLVENPNTTLIDASTAFRTSADWAYGLPELNRAQRERIRGAKRIAVPGCHASA
CCCCCCCEEEECCCCEEEECCHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHH
FVLAMRPLVDAGVVAPGFAAHSYSITGYSGGGKKMIADYEAGGAKLASPRPYALGLAHKH
HHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEECHHHHH
LPEMAAHTGLTSAPIFTPIVGPFYKGLAVTTYFTPGQLAKRVTPQNVQRVLAEHYAGEAF
HHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECCHHHHHCCCHHHHHHHHHHHCCCCEE
VRVAPYDAAENLDDGFFDVQANNDTNRVDLFVFGTAERFVTVARLDNLGKGASGAAIQCM
EEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEECHHHHEEHHHHHCCCCCCCCCEEEEE
NLNVGAAEGTGLAR
ECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]