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The map label for this gene is ftsW [H]

Identifier: 237813920

GI number: 237813920

Start: 3568038

End: 3569330

Strand: Reverse

Name: ftsW [H]

Synonym: GBP346_A3699

Alternate gene names: 237813920

Gene position: 3569330-3568038 (Counterclockwise)

Preceding gene: 237813921

Following gene: 237813919

Centisome position: 87.09

GC content: 66.59

Gene sequence:

>1293_bases
ATGAGCTGGTCCGATCGCCTCGTTTCCCGTTTCAACGGCGTCCGCGACGCGGGCGGCGCCGCCGTGCCGCGCACCGCCGC
ACGGGCGGCCTCGGGCGCGCGCGCGACGGCCGGCGGCCTCGCGAGCGTCGTGAACGGCGCGCGCCCGACCCGCTCGCGCA
TGCTCGACTTCGATTACTCGCTGCTGTGGGTATCGATCGCGCTGCTCGGGCTCGGCGTCGTGATGGTGTACTCGGCGTCG
ATCGCGATGCCGGATTCGCCGAAATACGCGTCATATCACGACTACGCATTCCTGCTGCGCCACTGCGTGTCGCTCGTCGT
CGCGTTCGTCGCGGCGGTGATCGCGTTCCGCGTGCCGGTGTCGACGTGGGACAAGTACGCGCCGCATCTTTTCCTGATCG
CGCTCGTCGGGCTCGTGATCGTGCTGATTCCGCACGTCGGCAAGGGCGTGAACGGCGCGCGCCGCTGGATTCCGCTCGGC
ATCACGAACATGCAGCCGTCGGAAATCATGAAGCTCGCGGTGACGATCTACGCGGCGAACTACACGGTGCGCAAGCAGGA
GTACATGCAGAGCTTCGCGAAAGGCTTTCTGCCGATGGCATGCGCGGTTGGCCTGGTCGGCGCGCTGCTGCTGCTCGAAC
CGGACATGGGCGCGTTCATGGTGATCGCCGCGATCGCGATGGGCGTGCTGTTCCTCGGCGGCGTGAACGGCAAGCTGTTC
GGCGGCCTCGTCGCGACGGCGGTCGGCACGTTCACGATGCTCGTGTGGCTGTCGCCGTGGCGGCGCGAGCGGATTTTCGC
GTATCTCGATCCCTGGGACGAGCGCTACGCGCAAGGCAAGGCGTACCAGCTCACGCATTCGCTGATCGCGTTCGGGCGCG
GCGAATGGTTCGGCGTCGGCCTGGGCGGCAGCGTCGAAAAGCTCAACTATCTGCCCGAAGCGCATACCGACTTCATTCTC
GCGGTGATCGGCGAGGAGCTCGGCTTTGTCGGCGTGCTCGTCGTGATCCTGCTGTTCTATTGGATCGTGCGCCGCGCGTT
CGAGATCGGCCGCCAGGCGCTTGCGCTCGACCGCACGTTCGCGGGGCTGATGGCAAAGGGCGTGGGCATCTGGTTCGGCG
CGCAGGCGTTCATCAACATGGGCGTGAACCTCGGCCTGCTGCCCACCAAGGGCCTCACGCTGCCGCTCGTGAGCTACGGC
GGCTCGGGCATTCTGCTGAATTGCGTCGCGCTCGCGGTGCTGCTGCGCGTCGATTATGAGAATCGCGTGCTGATGCGGGG
AGGAAAGGTATGA

Upstream 100 bases:

>100_bases
CCGCGTGCGCGAGCCTCGACATGTTCCGCAATTACGCACACCGGGCCGACGTGTTCCGCAGCGCGGTCGAAGATATCGCC
TTGGAAAAAGGAACGACGCT

Downstream 100 bases:

>100_bases
CCGCCCCGCGTCGGTACGCCGTTGCGGCGAAGGCGCATTGCATGCGCGCGGCGCGCGAAGCCGAGCCGCGCGGCCGTGGC
CGGACCGTTTGTTCATTCCT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSWSDRLVSRFNGVRDAGGAAVPRTAARAASGARATAGGLASVVNGARPTRSRMLDFDYSLLWVSIALLGLGVVMVYSAS
IAMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPVSTWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLG
ITNMQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMACAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLF
GGLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFIL
AVIGEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGVGIWFGAQAFINMGVNLGLLPTKGLTLPLVSYG
GSGILLNCVALAVLLRVDYENRVLMRGGKV

Sequences:

>Translated_430_residues
MSWSDRLVSRFNGVRDAGGAAVPRTAARAASGARATAGGLASVVNGARPTRSRMLDFDYSLLWVSIALLGLGVVMVYSAS
IAMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPVSTWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLG
ITNMQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMACAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLF
GGLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFIL
AVIGEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGVGIWFGAQAFINMGVNLGLLPTKGLTLPLVSYG
GSGILLNCVALAVLLRVDYENRVLMRGGKV
>Mature_429_residues
SWSDRLVSRFNGVRDAGGAAVPRTAARAASGARATAGGLASVVNGARPTRSRMLDFDYSLLWVSIALLGLGVVMVYSASI
AMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPVSTWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLGI
TNMQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMACAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLFG
GLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILA
VIGEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGVGIWFGAQAFINMGVNLGLLPTKGLTLPLVSYGG
SGILLNCVALAVLLRVDYENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=381, Percent_Identity=42.7821522309711, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=31.4868804664723, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46446; Mature: 46314

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEECCCCCC
>Mature Secondary Structure 
SWSDRLVSRFNGVRDAGGAAVPRTAARAASGARATAGGLASVVNGARPTRSRMLDFDYS
CHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHH
LLWVSIALLGLGVVMVYSASIAMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
STWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHEECC
YTVRKQEYMQSFAKGFLPMACAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
GGLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVG
HHHHHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCEEEEC
LGGSVEKLNYLPEAHTDFILAVIGEELGFVGVLVVILLFYWIVRRAFEIGRQALALDRTF
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLMAKGVGIWFGAQAFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCVALAVLLRVDYE
HHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCC
NRVLMRGGKV
CEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]