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The map label for this gene is gntP [H]

Identifier: 237813806

GI number: 237813806

Start: 3462231

End: 3463592

Strand: Reverse

Name: gntP [H]

Synonym: GBP346_A3584

Alternate gene names: 237813806

Gene position: 3463592-3462231 (Counterclockwise)

Preceding gene: 237813808

Following gene: 237813805

Centisome position: 84.51

GC content: 65.93

Gene sequence:

>1362_bases
ATGGGGGCTGTCCAAGGCAGCATGCTGCTGATTTACACCGTGATCGCGATCGCGGTGCTGATCCTGATGATCGCGCGCTA
CAAGGTGTATCCGTTCCTTGTGCTGATCATCGTGTCGCTCGGTCTCGGCCTCGCGGTCGGCATGCCGATGGACAAGATCG
TGAAATCGTTCGAGGGGGGCACGGGCGGCACGCTCGGCCACATCGCGATCGTCGTCGGCCTCGGCACGATGCTCGGCAAG
ATGATGGCCGAATCGGGCGGCGCCGAGCGGATCGCGACCACGCTGATCGACTGGTTCGGCGAGAAGAACATCCACTGGGC
GATGATGTTCGTCGCGATCATCGTCGGGTTGCCGGTGTTCTTCGAAGTCGGCTTCGTGCTGCTGATCCCGATCGCGTTCA
ACGTCGCGAAACGCACCGGCAAGTCGCTGCTCGTCGTCGGGCTGCCGATGGTGGCGGGCCTGTCGGTCGTGCACGGGCTG
ATTCCGCCGCACCCGGCGGCGCTCCTCGCCGTTCAGCAATACGGCGCCGACATCGGCAAGACGATCGCGTACGGCCTCAT
CGTCGGCGTGCCGACCGCGATCGTCGCGGGGCCGCTGTTCGCGCTCACGATCTCGAAGTTCGTGAAGCTGCCGGAGCACA
ATCCGCTCGCGTCGCAGTTCGTCGAGACGCGCGCGGCGGGCGAGACGCGCGAGCTGCCGAGCTTCGGCATCACGCTGTTC
ACGATCCTGCTGCCCGTCGTGCTGATGCTCGTCGGCAGCTGGGCCGATCTCGTGTTCGCGCCGAAATCGCTGCCGAACAG
CCTGCTGCGCTTCGCCGGCAATTCGGATGTCGCGCTCCTGATCGCCGTGCTCGTGAGCTTCTTCACGTTCGGCAAGCTGC
AGGGCTTCAATCGCGAGCAGATCCAGAAGTTCTGCGGCGATTGCCTCGCGCCGATCGCGGGCATCACGCTGATCGTCGGC
GCGGGCGGCGGCTTCGGCGGTATTCTGCGCGACAGCGGCATCTCGCAGCAGATCGTCGCGACCGCGACGCACGCGCATCT
GTCGCCGCTGCTGCTCGGCTGGTTCGTCGCGGCGCTGATCCGTCTCGCGACGGGTTCGGCCACCGTCGCGATGACGACCG
CCTGCGGGATCGTCGCGCCGATCGCCGCGGCCTCGGGCGTCACGGTGCGCCCGGAGCTGCTCGTGCTCGCGACGGGCTCG
GGCTCGCTCATCTTCTCGCACGTGAACGACGGCGGCTTCTGGCTGATCAAGGAATATTTCGGGATGACCGTGGGGCAGAC
GTTCAAGACGTGGACGCTGCTCGAAACGATCATCTCGGTGCTCGGTCTCACCTTCACGCTGGCGCTGAGCGCGGTTCTGT
AA

Upstream 100 bases:

>100_bases
AGCGTCCCGACGGGCGGCGAACCGCCTCGTTTCGGAGGCCTGCATAGCCGGACGGCGGCCCGCCGCGTCCGGCCCGATCT
ATCCCAAGGAGGAGTGCTAC

Downstream 100 bases:

>100_bases
CAAGGGGTAGTCAATGATTCTGATCGCAATGGGCGTGTCGGGCGCGGGCAAGTCGCGGATCGGCGAAATGCTCGCGCAAC
GCCTGTCGTGCAGCTATACC

Product: transporter, gluconate:H+ symporter (GntP) family

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGAVQGSMLLIYTVIAIAVLILMIARYKVYPFLVLIIVSLGLGLAVGMPMDKIVKSFEGGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAYGLIVGVPTAIVAGPLFALTISKFVKLPEHNPLASQFVETRAAGETRELPSFGITLF
TILLPVVLMLVGSWADLVFAPKSLPNSLLRFAGNSDVALLIAVLVSFFTFGKLQGFNREQIQKFCGDCLAPIAGITLIVG
AGGGFGGILRDSGISQQIVATATHAHLSPLLLGWFVAALIRLATGSATVAMTTACGIVAPIAAASGVTVRPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWTLLETIISVLGLTFTLALSAVL

Sequences:

>Translated_453_residues
MGAVQGSMLLIYTVIAIAVLILMIARYKVYPFLVLIIVSLGLGLAVGMPMDKIVKSFEGGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAYGLIVGVPTAIVAGPLFALTISKFVKLPEHNPLASQFVETRAAGETRELPSFGITLF
TILLPVVLMLVGSWADLVFAPKSLPNSLLRFAGNSDVALLIAVLVSFFTFGKLQGFNREQIQKFCGDCLAPIAGITLIVG
AGGGFGGILRDSGISQQIVATATHAHLSPLLLGWFVAALIRLATGSATVAMTTACGIVAPIAAASGVTVRPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWTLLETIISVLGLTFTLALSAVL
>Mature_452_residues
GAVQGSMLLIYTVIAIAVLILMIARYKVYPFLVLIIVSLGLGLAVGMPMDKIVKSFEGGTGGTLGHIAIVVGLGTMLGKM
MAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGLI
PPHPAALLAVQQYGADIGKTIAYGLIVGVPTAIVAGPLFALTISKFVKLPEHNPLASQFVETRAAGETRELPSFGITLFT
ILLPVVLMLVGSWADLVFAPKSLPNSLLRFAGNSDVALLIAVLVSFFTFGKLQGFNREQIQKFCGDCLAPIAGITLIVGA
GGGFGGILRDSGISQQIVATATHAHLSPLLLGWFVAALIRLATGSATVAMTTACGIVAPIAAASGVTVRPELLVLATGSG
SLIFSHVNDGGFWLIKEYFGMTVGQTFKTWTLLETIISVLGLTFTLALSAVL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=450, Percent_Identity=46.4444444444444, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1790716, Length=449, Percent_Identity=43.652561247216, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=42.247191011236, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI2367370, Length=455, Percent_Identity=41.5384615384615, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI1790776, Length=448, Percent_Identity=33.9285714285714, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI48994939, Length=435, Percent_Identity=36.7816091954023, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789097, Length=454, Percent_Identity=33.920704845815, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47384; Mature: 47253

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GAVQGSMLLIYTVIAIAVLILMIARYKVYPFLVLIIVSLGLGLAVGMPMDKIVKSFEGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA