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The map label for this gene is aroK_1 [H]

Identifier: 237813805

GI number: 237813805

Start: 3461699

End: 3462217

Strand: Reverse

Name: aroK_1 [H]

Synonym: GBP346_A3583

Alternate gene names: 237813805

Gene position: 3462217-3461699 (Counterclockwise)

Preceding gene: 237813806

Following gene: 237813802

Centisome position: 84.47

GC content: 65.7

Gene sequence:

>519_bases
ATGATTCTGATCGCAATGGGCGTGTCGGGCGCGGGCAAGTCGCGGATCGGCGAAATGCTCGCGCAACGCCTGTCGTGCAG
CTATACCGACGGCGACGCGTTTCACAGCGCCGCCAACAAGGAAAAGATGCACCACGGGATTGCGTTGACCGACGAGGACC
GCTGGCCGTGGCTGCGCTCGATCCGCGAGGCCATCGAGGCGAGGCAGCGCGCGGGCGAAACCGCGGTGTTCACGTGCTCT
TCGCTCAAGCGCGCGTACCGCGACATCCTGCGCGGCAACGATCGCGACGTGCGCTTCGTCTATCTGAAGGGGTCGTTCGA
CGTGCTGCGCGAGCGGCTGAAGACGCGCACCGGGCACTTCTTCGATCCGTCGCTGCTGCAGAGCCAGCTCGACACGCTCG
AGGAGCCGGGCCCGGACGAGGCGATCGAAGTCAGCATCGAGTTGACGCCCGACGAGATCGTCGAGCGCGTGATGCGCGAG
CTCGACCGCGAGCAGCAGCAGCAACAGCAGCAACAGTGA

Upstream 100 bases:

>100_bases
CAGACGTTCAAGACGTGGACGCTGCTCGAAACGATCATCTCGGTGCTCGGTCTCACCTTCACGCTGGCGCTGAGCGCGGT
TCTGTAACAAGGGGTAGTCA

Downstream 100 bases:

>100_bases
CGGCGCGCGGCCGCGAAGCGGCCGCAAAAAGAAAGGCGCCCCGCGAACCGCGGGGCGCCTTTTTCACATCGCGTCGCCGA
CGCGCGTGATACGTTACGCG

Product: shikimate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MILIAMGVSGAGKSRIGEMLAQRLSCSYTDGDAFHSAANKEKMHHGIALTDEDRWPWLRSIREAIEARQRAGETAVFTCS
SLKRAYRDILRGNDRDVRFVYLKGSFDVLRERLKTRTGHFFDPSLLQSQLDTLEEPGPDEAIEVSIELTPDEIVERVMRE
LDREQQQQQQQQ

Sequences:

>Translated_172_residues
MILIAMGVSGAGKSRIGEMLAQRLSCSYTDGDAFHSAANKEKMHHGIALTDEDRWPWLRSIREAIEARQRAGETAVFTCS
SLKRAYRDILRGNDRDVRFVYLKGSFDVLRERLKTRTGHFFDPSLLQSQLDTLEEPGPDEAIEVSIELTPDEIVERVMRE
LDREQQQQQQQQ
>Mature_172_residues
MILIAMGVSGAGKSRIGEMLAQRLSCSYTDGDAFHSAANKEKMHHGIALTDEDRWPWLRSIREAIEARQRAGETAVFTCS
SLKRAYRDILRGNDRDVRFVYLKGSFDVLRERLKTRTGHFFDPSLLQSQLDTLEEPGPDEAIEVSIELTPDEIVERVMRE
LDREQQQQQQQQ

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=178, Percent_Identity=39.3258426966292, Blast_Score=131, Evalue=3e-31,
Organism=Escherichia coli, GI87082265, Length=139, Percent_Identity=46.7625899280576, Blast_Score=144, Evalue=2e-36,
Organism=Escherichia coli, GI1790719, Length=149, Percent_Identity=44.2953020134228, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25146487, Length=164, Percent_Identity=42.0731707317073, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320454, Length=156, Percent_Identity=35.8974358974359, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19708; Mature: 19708

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIAMGVSGAGKSRIGEMLAQRLSCSYTDGDAFHSAANKEKMHHGIALTDEDRWPWLRS
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHH
IREAIEARQRAGETAVFTCSSLKRAYRDILRGNDRDVRFVYLKGSFDVLRERLKTRTGHF
HHHHHHHHHHCCCHHEEEHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCC
FDPSLLQSQLDTLEEPGPDEAIEVSIELTPDEIVERVMRELDREQQQQQQQQ
CCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILIAMGVSGAGKSRIGEMLAQRLSCSYTDGDAFHSAANKEKMHHGIALTDEDRWPWLRS
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHH
IREAIEARQRAGETAVFTCSSLKRAYRDILRGNDRDVRFVYLKGSFDVLRERLKTRTGHF
HHHHHHHHHHCCCHHEEEHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCC
FDPSLLQSQLDTLEEPGPDEAIEVSIELTPDEIVERVMRELDREQQQQQQQQ
CCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]