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The map label for this gene is yfcG [H]

Identifier: 237813772

GI number: 237813772

Start: 3435429

End: 3436127

Strand: Reverse

Name: yfcG [H]

Synonym: GBP346_A3549

Alternate gene names: 237813772

Gene position: 3436127-3435429 (Counterclockwise)

Preceding gene: 237813773

Following gene: 237813770

Centisome position: 83.84

GC content: 66.95

Gene sequence:

>699_bases
ATGATCGATCTCTACTACTGGACGACGCCGAACGGCCACAAGATCACGATGTTCCTGGAGGAGGCGGGCCTGCCGTACCG
GATCGTGCCGGTGAACATCGGCCGCGGCGAGCAATTCGAGCCGGCGTTCCTGCGCATCGCGCCGAACAACCGGATTCCCG
CGCTCGTCGACCACGCGCCCGCCGACGGCGGCGCGCCGCTGTCGATCTTCGAATCGGGCGCGATCCTGCTGTACCTCGCG
GACAAGCTCGGGCGCTTCATTCCCGCCGATCTGCGCGGCCGCAACGAGACGCTGCAGTGGTTGTTCTGGCAGATGGGCGG
GCTCGGCCCGATGGCGGGGCAGAACCATCATTTCGTGCAGTACGCGCCCGAGCCGCTGCCGTATGCGATCGAGCGGTACG
TGAAGGAGACGTCGCGGTTGTACGGCGTGCTGAACAAGCATCTGTCGGACGGGCGCGACTACATCGCGGGCGAATATTCG
ATCGCCGACATGGCGAGCTACCCGTGGATCGTGCCGCACGAGCGGCAGCGGCAGCGCCTCGAGGATTTTCCATTCCTGGC
CGCATGGTTCGCGCGGGTCGCCGAACGGCCGGGCACCGTGCGCGCCTATGCACGGGCGAAGGAGATCAACACGGCGCCGA
CGGTCGATCAGCAGTCGCGCGGCGTGTTGTTCGGGCAGGACGCGAGCACGGTCCGCTGA

Upstream 100 bases:

>100_bases
CGCCATGCGTTCAAGGTCGAGTTCGACGACGAGGCGCGCCGCGCGCTGTTTCCGCAGAACGCGCGGCTCGCGGCCACGGC
CGGGACGGGAGCCTGACGCG

Downstream 100 bases:

>100_bases
CAGGGGACTGGGCGGTCGGCGGGCTTCGGCCCGGCCGCCGCCGTGCGGGCGCGGTCGGGCGCGGGCGCGCCGCGCAACGG
GGCGGGCTTCGGCCCGGCCC

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAPADGGAPLSIFESGAILLYLA
DKLGRFIPADLRGRNETLQWLFWQMGGLGPMAGQNHHFVQYAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYS
IADMASYPWIVPHERQRQRLEDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR

Sequences:

>Translated_232_residues
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAPADGGAPLSIFESGAILLYLA
DKLGRFIPADLRGRNETLQWLFWQMGGLGPMAGQNHHFVQYAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYS
IADMASYPWIVPHERQRQRLEDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR
>Mature_232_residues
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAPADGGAPLSIFESGAILLYLA
DKLGRFIPADLRGRNETLQWLFWQMGGLGPMAGQNHHFVQYAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYS
IADMASYPWIVPHERQRQRLEDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=208, Percent_Identity=60.0961538461538, Blast_Score=254, Evalue=3e-69,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=39.7196261682243, Blast_Score=150, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=31.1965811965812, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28571670, Length=192, Percent_Identity=28.125, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17864596, Length=212, Percent_Identity=27.8301886792453, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26247; Mature: 26247

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAP
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
ADGGAPLSIFESGAILLYLADKLGRFIPADLRGRNETLQWLFWQMGGLGPMAGQNHHFVQ
CCCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYSIADMASYPWIVPHERQRQRL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCEECCCHHHHHHH
EDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR
HCCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAP
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
ADGGAPLSIFESGAILLYLADKLGRFIPADLRGRNETLQWLFWQMGGLGPMAGQNHHFVQ
CCCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYSIADMASYPWIVPHERQRQRL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCEECCCHHHHHHH
EDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR
HCCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]