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The map label for this gene is yrbI [C]

Identifier: 237813614

GI number: 237813614

Start: 3268315

End: 3268866

Strand: Reverse

Name: yrbI [C]

Synonym: GBP346_A3391

Alternate gene names: 237813614

Gene position: 3268866-3268315 (Counterclockwise)

Preceding gene: 237813615

Following gene: 237813613

Centisome position: 79.76

GC content: 69.57

Gene sequence:

>552_bases
ATGAGCGCGCCGGCGTATCGCGGTGCGATTCGGCTCGTGCTGTTCGACGTCGACGGCGTGCTGACCGACGGGCGGCTGCA
TGTGACGGGCGACGGAGAGTGCATGAAGAGCTTCCATGCGAAGGACGGCATCGCCGTTGCGCTGCTGCACGCGCACGGCA
TTCGCAGCGGCATTCTGTCGGGCCGCCACAGCGAGGCGCTCGCATGGCGCGCGCGGCAGCTCGGTTTCGACGTGTGCGTG
TCGGGCTGCGGCGACAAGCGCGCAGGCTACGCGCGCATCAAGTCCGAACAGGCGCTCGCGGACCATGCGATCGCGTATGT
CGGCGACGACGTCAACGATCTGCCCGTGATCGACGCGGTCGGCGTCTCGTACGCGCCCGCCGACGCGCACGTGCTCGTCA
GGCGGCGCGTCGACTACGTCGTCTCGCGCGCGGGTGGCGAGGGCGCCGCGCGGGAGGTCGCCGAGCACGTGCTGTTGCGC
TCGGGGTTGTCGCTCGACGACGCATATCGGCCGTTGCTCGACGAATGGGCTCGGCATGCCGTCGTCCAATGA

Upstream 100 bases:

>100_bases
ATGGGCCGAGCGCGCTGCCGTTGCATCAGCTCGAGGGCTTCCTGTCGCAGATGAAGGCGATCGACGATCTCGTCAAGCGC
ATGCCGGCGCTCGAGATTCG

Downstream 100 bases:

>100_bases
GGGCGCCGCGCGCCGCAGCGGCCGCCGGCTTCATGCAGCGTGCGTGCGACGGTGCGCGCCGCAATATTCCCCCCATTTTC
CATGGCCCATGACGGCTCCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSAPAYRGAIRLVLFDVDGVLTDGRLHVTGDGECMKSFHAKDGIAVALLHAHGIRSGILSGRHSEALAWRARQLGFDVCV
SGCGDKRAGYARIKSEQALADHAIAYVGDDVNDLPVIDAVGVSYAPADAHVLVRRRVDYVVSRAGGEGAAREVAEHVLLR
SGLSLDDAYRPLLDEWARHAVVQ

Sequences:

>Translated_183_residues
MSAPAYRGAIRLVLFDVDGVLTDGRLHVTGDGECMKSFHAKDGIAVALLHAHGIRSGILSGRHSEALAWRARQLGFDVCV
SGCGDKRAGYARIKSEQALADHAIAYVGDDVNDLPVIDAVGVSYAPADAHVLVRRRVDYVVSRAGGEGAAREVAEHVLLR
SGLSLDDAYRPLLDEWARHAVVQ
>Mature_182_residues
SAPAYRGAIRLVLFDVDGVLTDGRLHVTGDGECMKSFHAKDGIAVALLHAHGIRSGILSGRHSEALAWRARQLGFDVCVS
GCGDKRAGYARIKSEQALADHAIAYVGDDVNDLPVIDAVGVSYAPADAHVLVRRRVDYVVSRAGGEGAAREVAEHVLLRS
GLSLDDAYRPLLDEWARHAVVQ

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=150, Percent_Identity=35.3333333333333, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI2367202, Length=159, Percent_Identity=40.251572327044, Blast_Score=113, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19606; Mature: 19475

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPAYRGAIRLVLFDVDGVLTDGRLHVTGDGECMKSFHAKDGIAVALLHAHGIRSGILS
CCCCCCCCEEEEEEEECCCEEECCEEEEECCHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
GRHSEALAWRARQLGFDVCVSGCGDKRAGYARIKSEQALADHAIAYVGDDVNDLPVIDAV
CCCHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCC
GVSYAPADAHVLVRRRVDYVVSRAGGEGAAREVAEHVLLRSGLSLDDAYRPLLDEWARHA
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VVQ
CCC
>Mature Secondary Structure 
SAPAYRGAIRLVLFDVDGVLTDGRLHVTGDGECMKSFHAKDGIAVALLHAHGIRSGILS
CCCCCCCEEEEEEEECCCEEECCEEEEECCHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
GRHSEALAWRARQLGFDVCVSGCGDKRAGYARIKSEQALADHAIAYVGDDVNDLPVIDAV
CCCHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCC
GVSYAPADAHVLVRRRVDYVVSRAGGEGAAREVAEHVLLRSGLSLDDAYRPLLDEWARHA
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VVQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12639950; 11835514 [H]