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The map label for this gene is kdsA_2

Identifier: 237813615

GI number: 237813615

Start: 3268863

End: 3269708

Strand: Reverse

Name: kdsA_2

Synonym: GBP346_A3392

Alternate gene names: 237813615

Gene position: 3269708-3268863 (Counterclockwise)

Preceding gene: 237813616

Following gene: 237813614

Centisome position: 79.78

GC content: 65.84

Gene sequence:

>846_bases
ATGAACGTAGCAATCAGCCCCGGCGTCACGGCCGGCAACAGCCTGCCTTTCGTGCTGTTCGGCGGGATCAACGTGCTCGA
GAGTCTCGACTTCACGCTCGACGTGTGCGGCGAATACGTCGCGGTGACGCGCAAGCTCGGCATTCCGTTCGTGTTCAAGG
CGTCGTTCGACAAGGCGAACCGCTCGTCGATCCATTCGTATCGCGGCGTCGGGCTCGACGAAGGCCTGAAGATCTTCGCC
GAGGTGAAGGCGCGCTTCGGCGTGCCGGTGATCACCGATGTGCACGAAGTCGAGCAGGCGGCGCCCGTGGCCGAAATCGC
CGACGTGTTGCAGGTGCCCGCGTTTCTCGCGCGGCAGACCGATCTCGTCGTCGCGATCGCGAAGGCCGGCAAGCCGGTGA
ACGTGAAGAAGCCGCAGTTCATGAGCCCCACGCAATTGAAGCACGTGGTGTCGAAATGCGGCGAGGTCGGCAACGATCGC
GTGATGCTGTGCGAGCGCGGCAGTTCGTTCGGCTACGACAATCTCGTCGTGGACATGCTCGGCTTCCGGCAGATGGCCGA
GACGACGGGCGGTTGCCCGGTGATCTTCGACGTCACGCACAGCCTGCAGTGCCGCGATCCGCTCGGCGACGCGTCGGGCG
GCCGGCGCCGGCAAGTGCTCGATCTCGCGCGCGCGGGCATCGCGGTTGGCATCGCGGGGCTCTTTCTCGAGGCGCACCCC
GATCCCGACCGCGCGCGCTGCGATGGGCCGAGCGCGCTGCCGTTGCATCAGCTCGAGGGCTTCCTGTCGCAGATGAAGGC
GATCGACGATCTCGTCAAGCGCATGCCGGCGCTCGAGATTCGATGA

Upstream 100 bases:

>100_bases
CGCGCGCGTATCTTGAGGATTCGCCGCCCCGAGCGTCACGCGCCGCCGCATGGCATCGGCGCGCGGCGCGCACGAGGCGG
CCCATTGGGAGATTTGACCT

Downstream 100 bases:

>100_bases
GCGCGCCGGCGTATCGCGGTGCGATTCGGCTCGTGCTGTTCGACGTCGACGGCGTGCTGACCGACGGGCGGCTGCATGTG
ACGGGCGACGGAGAGTGCAT

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase 2; KDO-8-phosphate synthase 2; KDO 8-P synthase 2; KDOPS 2; Phospho-2-dehydro-3-deoxyoctonate aldolase 2

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFA
EVKARFGVPVITDVHEVEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDR
VMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHP
DPDRARCDGPSALPLHQLEGFLSQMKAIDDLVKRMPALEIR

Sequences:

>Translated_281_residues
MNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFA
EVKARFGVPVITDVHEVEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDR
VMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHP
DPDRARCDGPSALPLHQLEGFLSQMKAIDDLVKRMPALEIR
>Mature_281_residues
MNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFA
EVKARFGVPVITDVHEVEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDR
VMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHP
DPDRARCDGPSALPLHQLEGFLSQMKAIDDLVKRMPALEIR

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family

Homologues:

Organism=Escherichia coli, GI1787466, Length=271, Percent_Identity=68.6346863468635, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): KDSA2_BURPS (Q63RA1)

Other databases:

- EMBL:   BX571965
- RefSeq:   YP_109367.1
- ProteinModelPortal:   Q63RA1
- SMR:   Q63RA1
- GeneID:   3093882
- GenomeReviews:   BX571965_GR
- KEGG:   bps:BPSL2772
- HOGENOM:   HBG575990
- OMA:   EITFAND
- PhylomeDB:   Q63RA1
- ProtClustDB:   PRK12457
- BioCyc:   BPSE272560:BPSL2772-MONOMER
- BRENDA:   2.5.1.55
- GO:   GO:0005737
- HAMAP:   MF_00056
- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR21057:SF2
- TIGRFAMs:   TIGR01362

Pfam domain/function: PF00793 DAHP_synth_1

EC number: =2.5.1.55

Molecular weight: Translated: 30213; Mature: 30213

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKAN
CCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEVEQAAPVAEIADVLQVPAFLARQT
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDML
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
GFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHP
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCC
DPDRARCDGPSALPLHQLEGFLSQMKAIDDLVKRMPALEIR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKAN
CCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEVEQAAPVAEIADVLQVPAFLARQT
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDML
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
GFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHP
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCC
DPDRARCDGPSALPLHQLEGFLSQMKAIDDLVKRMPALEIR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA