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The map label for this gene is yafC [H]

Identifier: 237813571

GI number: 237813571

Start: 3232557

End: 3233537

Strand: Direct

Name: yafC [H]

Synonym: GBP346_A3347

Alternate gene names: 237813571

Gene position: 3232557-3233537 (Clockwise)

Preceding gene: 237813570

Following gene: 237813572

Centisome position: 78.87

GC content: 67.18

Gene sequence:

>981_bases
ATGAACCAAATCCAGACCATGCGTGTCTTCGTATGTGTTGCCGAACTGCAGAGCTTCCGCCGGGCGGCGCGGAAACTCGG
CGTATCGAATGCGCTCGTCACGCGTTCGATCGCGATGCTCGAAACACATCTGAACACGCGTCTCATCCATCGTACGACAC
GCAATCTGTCGCTGACGGAAGCGGGCATCCGCTATCTCGACGGCTGCAGGGCGCTCCTCGAGGAGTTCGATCAGCTCGAG
GCGTCCGTCGAGCGGGCGGTGCACGAGCCCGTCGGCACATTGCGCGTGGCCGTGTCCGGGTTGCTGTCGCCCGGCCGGAT
CACCCCGCTCGTCGACAGCTACCGGCGCCAGTACCCGAAGGTGCGCGTGCAACTGACGCTCACCGAGGGCGCGCTCGACG
TGATCGAAGCCGGCTACGACGCGGGCCTCGTCACGGGCGGCCGCCTCGACGGCAACCCGGCGCTGATCGGCCATCCGCTG
ATGCCGAACACGCTCGCGCTCTGCGCGGCGCCTTCGTACATCGAGCGGCACGGCGCGCCGCACCGCCCCGACGATCTGGT
CCGCCACGCGTGCATCGCGCTGCCGGCCGACCAGCATGCGTCGACCTGGCGCTTCGTCGATCCGGACCACTTCACGCATG
TCGTCTCGCTGCAGCCCGTCTACACGGTCAACAGCGCTTCGATGGTGCGCGCGGCAACGCTCGCCGGCACCGGCATTTCG
GTGCTGCCGGAGAGCTACATCGCCGATGCGCTCGAAAGCGGCGAGCTCGTGCGGATCCTCGGCGACTACCGGATCGACGA
TCCCGATACGCAGTTGTCGATCGTCTATCCGAACCGCCAGTTCCTGCCGGCGCGCACCCGCAGCTTCGTCGAGCACGCGC
TGTATCACCTCGGCGGGCAGAAGACCGAGACGAACGGCCACTACTTCATGCGCGAAGCCGGCACGGCGAAGCGCCCGGAC
GTCGTCACCGGGCTCCAGTGA

Upstream 100 bases:

>100_bases
TCGTTATTTAAGACAAGCCCAGTGCTGATCCGACAGCCTGCGGCTCGCCAGATCGAAGGCGAAAAACACAACATAATCAT
TTAATGGGCCAACGAAAGCT

Downstream 100 bases:

>100_bases
CGCCCGACTGAAGTAAACTGACGCGCACCTTTACCGGAGGCAAAGCGTGCGCGTGATTCTTTTCAGCAGCCGGCAGTACG
ACCACGATTCGTTCGATGCC

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNQIQTMRVFVCVAELQSFRRAARKLGVSNALVTRSIAMLETHLNTRLIHRTTRNLSLTEAGIRYLDGCRALLEEFDQLE
ASVERAVHEPVGTLRVAVSGLLSPGRITPLVDSYRRQYPKVRVQLTLTEGALDVIEAGYDAGLVTGGRLDGNPALIGHPL
MPNTLALCAAPSYIERHGAPHRPDDLVRHACIALPADQHASTWRFVDPDHFTHVVSLQPVYTVNSASMVRAATLAGTGIS
VLPESYIADALESGELVRILGDYRIDDPDTQLSIVYPNRQFLPARTRSFVEHALYHLGGQKTETNGHYFMREAGTAKRPD
VVTGLQ

Sequences:

>Translated_326_residues
MNQIQTMRVFVCVAELQSFRRAARKLGVSNALVTRSIAMLETHLNTRLIHRTTRNLSLTEAGIRYLDGCRALLEEFDQLE
ASVERAVHEPVGTLRVAVSGLLSPGRITPLVDSYRRQYPKVRVQLTLTEGALDVIEAGYDAGLVTGGRLDGNPALIGHPL
MPNTLALCAAPSYIERHGAPHRPDDLVRHACIALPADQHASTWRFVDPDHFTHVVSLQPVYTVNSASMVRAATLAGTGIS
VLPESYIADALESGELVRILGDYRIDDPDTQLSIVYPNRQFLPARTRSFVEHALYHLGGQKTETNGHYFMREAGTAKRPD
VVTGLQ
>Mature_326_residues
MNQIQTMRVFVCVAELQSFRRAARKLGVSNALVTRSIAMLETHLNTRLIHRTTRNLSLTEAGIRYLDGCRALLEEFDQLE
ASVERAVHEPVGTLRVAVSGLLSPGRITPLVDSYRRQYPKVRVQLTLTEGALDVIEAGYDAGLVTGGRLDGNPALIGHPL
MPNTLALCAAPSYIERHGAPHRPDDLVRHACIALPADQHASTWRFVDPDHFTHVVSLQPVYTVNSASMVRAATLAGTGIS
VLPESYIADALESGELVRILGDYRIDDPDTQLSIVYPNRQFLPARTRSFVEHALYHLGGQKTETNGHYFMREAGTAKRPD
VVTGLQ

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=30.7167235494881, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=29.8013245033113, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=30.1369863013699, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789639, Length=267, Percent_Identity=29.5880149812734, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=27.2727272727273, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=28.719723183391, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=28.4615384615385, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1787879, Length=307, Percent_Identity=27.6872964169381, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693105, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=294, Percent_Identity=25.1700680272109, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=291, Percent_Identity=24.0549828178694, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788748, Length=122, Percent_Identity=33.6065573770492, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=253, Percent_Identity=25.6916996047431, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35906; Mature: 35906

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIQTMRVFVCVAELQSFRRAARKLGVSNALVTRSIAMLETHLNTRLIHRTTRNLSLTE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AGIRYLDGCRALLEEFDQLEASVERAVHEPVGTLRVAVSGLLSPGRITPLVDSYRRQYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCE
VRVQLTLTEGALDVIEAGYDAGLVTGGRLDGNPALIGHPLMPNTLALCAAPSYIERHGAP
EEEEEEEECCHHHHHHCCCCCCEEECCEECCCCCEEECCCCCCHHHHHCCCHHHHHCCCC
HRPDDLVRHACIALPADQHASTWRFVDPDHFTHVVSLQPVYTVNSASMVRAATLAGTGIS
CCHHHHHHHHHHCCCCCCCCCCCCEECCCCCEEEEEECEEEEECCHHHHHHHHHCCCCHH
VLPESYIADALESGELVRILGDYRIDDPDTQLSIVYPNRQFLPARTRSFVEHALYHLGGQ
HCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
KTETNGHYFMREAGTAKRPDVVTGLQ
CCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQIQTMRVFVCVAELQSFRRAARKLGVSNALVTRSIAMLETHLNTRLIHRTTRNLSLTE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AGIRYLDGCRALLEEFDQLEASVERAVHEPVGTLRVAVSGLLSPGRITPLVDSYRRQYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCE
VRVQLTLTEGALDVIEAGYDAGLVTGGRLDGNPALIGHPLMPNTLALCAAPSYIERHGAP
EEEEEEEECCHHHHHHCCCCCCEEECCEECCCCCEEECCCCCCHHHHHCCCHHHHHCCCC
HRPDDLVRHACIALPADQHASTWRFVDPDHFTHVVSLQPVYTVNSASMVRAATLAGTGIS
CCHHHHHHHHHHCCCCCCCCCCCCEECCCCCEEEEEECEEEEECCHHHHHHHHHCCCCHH
VLPESYIADALESGELVRILGDYRIDDPDTQLSIVYPNRQFLPARTRSFVEHALYHLGGQ
HCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
KTETNGHYFMREAGTAKRPDVVTGLQ
CCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]