Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 237813555

GI number: 237813555

Start: 3214021

End: 3214968

Strand: Direct

Name: nahR [H]

Synonym: GBP346_A3331

Alternate gene names: 237813555

Gene position: 3214021-3214968 (Clockwise)

Preceding gene: 237813554

Following gene: 237813560

Centisome position: 78.42

GC content: 71.41

Gene sequence:

>948_bases
ATGCAACCGGATCAGGATCGCGCCGCCTCGCTCGACATCTGGCTCGTGCGCGTGCTGCGCACGCTGCTCGTCGAGCGCAG
CGTGACGCAGGCCGCGCTGCGACTGAACCAGACGCAGCCCGCGATCAGCGCCGCGCTGCGCAAGCTGCGCGACGCGCTGG
GCGACCCCTTGCTCGTGCGCGGCAAGACGGGCATGGTGCCGACCGAGTACGGCGCGTCGCTCCTCGACGCGGCCGAGCGC
GCGCTGCGCGACGTGGACTTCGTCGCGACGCCGCACGGCCCGTTCGATCCCGATACCGCGCGCCGCACGTTCCGGATCGC
CGCGCCCGACTATCTGAACGACTTCTTCATGCCGACGCTCGTCGCGCGCTTTCGCGCGGCCGCGCCGCATGCGCGCATCG
AGATCGATTCGCTGAATCCGTCGCTCGATCACGCGGGCGCGCTCGATTCAGGCGCGCTCGATCTCGTGATCGGCAACTGG
CCGAAGCCCGATCCGCGCTTCGTGCGCACCGATCTGTTCTCCGACACCGTCGTCTGCCTGATGCGGCGCGACCATCCGCT
CGCGCGCGCGCCGCTCACGCGCGACGCGTACGCGAACGCCTTGCATCTCGCGCCCGCGCCGTACATCGGCGCGCGCAACA
ACGCGATCGAGCTCGGTCTCGCGCGGGCGGGCATCGCGCGGCGCGTCGCCGCGACGCTGCCGTACTTCGGCCTCGTGCCG
CAGGTGCTGCTGCAATCGGACCTGATCTTCACGACGACGCGGCGCTTCGCGATCCACTACGCGCGACTGCTGCCGCTCGT
CGTCGTCGCGCCGCCCGTGCCGTTTCCGCGCATCCGGTGCTATCAGCTGCGGCACCCGGCGCCCGATCGTCCAACCGACG
CCGACTGGCTGAGCGCGCTGATGGCCGACGTGTCGGCCGAGCTGACGATGCGCGGCAAGCGGCGCTGA

Upstream 100 bases:

>100_bases
AGCACGCTGCCGTCGGGCCTCGCATGATGCCGCCCGCCGCGCCGCATCGCGGGCGCGCGGCGCGCGAGGCGCGCGCCTGA
CGCCGCCCCGCCCGCAGCAG

Downstream 100 bases:

>100_bases
GCGAGCCGGCGAACGCGGCGCGCAACCGCGCCATGCCGCGCGCGACGCCTCGATTCGCCGTGCGAAGCCGGCGCGCCGGC
GTTCACCGCCGCCGCATCAG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQPDQDRAASLDIWLVRVLRTLLVERSVTQAALRLNQTQPAISAALRKLRDALGDPLLVRGKTGMVPTEYGASLLDAAER
ALRDVDFVATPHGPFDPDTARRTFRIAAPDYLNDFFMPTLVARFRAAAPHARIEIDSLNPSLDHAGALDSGALDLVIGNW
PKPDPRFVRTDLFSDTVVCLMRRDHPLARAPLTRDAYANALHLAPAPYIGARNNAIELGLARAGIARRVAATLPYFGLVP
QVLLQSDLIFTTTRRFAIHYARLLPLVVVAPPVPFPRIRCYQLRHPAPDRPTDADWLSALMADVSAELTMRGKRR

Sequences:

>Translated_315_residues
MQPDQDRAASLDIWLVRVLRTLLVERSVTQAALRLNQTQPAISAALRKLRDALGDPLLVRGKTGMVPTEYGASLLDAAER
ALRDVDFVATPHGPFDPDTARRTFRIAAPDYLNDFFMPTLVARFRAAAPHARIEIDSLNPSLDHAGALDSGALDLVIGNW
PKPDPRFVRTDLFSDTVVCLMRRDHPLARAPLTRDAYANALHLAPAPYIGARNNAIELGLARAGIARRVAATLPYFGLVP
QVLLQSDLIFTTTRRFAIHYARLLPLVVVAPPVPFPRIRCYQLRHPAPDRPTDADWLSALMADVSAELTMRGKRR
>Mature_315_residues
MQPDQDRAASLDIWLVRVLRTLLVERSVTQAALRLNQTQPAISAALRKLRDALGDPLLVRGKTGMVPTEYGASLLDAAER
ALRDVDFVATPHGPFDPDTARRTFRIAAPDYLNDFFMPTLVARFRAAAPHARIEIDSLNPSLDHAGALDSGALDLVIGNW
PKPDPRFVRTDLFSDTVVCLMRRDHPLARAPLTRDAYANALHLAPAPYIGARNNAIELGLARAGIARRVAATLPYFGLVP
QVLLQSDLIFTTTRRFAIHYARLLPLVVVAPPVPFPRIRCYQLRHPAPDRPTDADWLSALMADVSAELTMRGKRR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=300, Percent_Identity=24.6666666666667, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790147, Length=277, Percent_Identity=28.5198555956679, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081766, Length=279, Percent_Identity=24.0143369175627, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34866; Mature: 34866

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPDQDRAASLDIWLVRVLRTLLVERSVTQAALRLNQTQPAISAALRKLRDALGDPLLVR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEE
GKTGMVPTEYGASLLDAAERALRDVDFVATPHGPFDPDTARRTFRIAAPDYLNDFFMPTL
CCCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHCEEEEECCHHHHHHHHHHH
VARFRAAAPHARIEIDSLNPSLDHAGALDSGALDLVIGNWPKPDPRFVRTDLFSDTVVCL
HHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
MRRDHPLARAPLTRDAYANALHLAPAPYIGARNNAIELGLARAGIARRVAATLPYFGLVP
HHCCCCCCCCCCCHHHHHCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHH
QVLLQSDLIFTTTRRFAIHYARLLPLVVVAPPVPFPRIRCYQLRHPAPDRPTDADWLSAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
MADVSAELTMRGKRR
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MQPDQDRAASLDIWLVRVLRTLLVERSVTQAALRLNQTQPAISAALRKLRDALGDPLLVR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEE
GKTGMVPTEYGASLLDAAERALRDVDFVATPHGPFDPDTARRTFRIAAPDYLNDFFMPTL
CCCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHCEEEEECCHHHHHHHHHHH
VARFRAAAPHARIEIDSLNPSLDHAGALDSGALDLVIGNWPKPDPRFVRTDLFSDTVVCL
HHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
MRRDHPLARAPLTRDAYANALHLAPAPYIGARNNAIELGLARAGIARRVAATLPYFGLVP
HHCCCCCCCCCCCHHHHHCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHH
QVLLQSDLIFTTTRRFAIHYARLLPLVVVAPPVPFPRIRCYQLRHPAPDRPTDADWLSAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
MADVSAELTMRGKRR
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]