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The map label for this gene is pgl [H]

Identifier: 237813416

GI number: 237813416

Start: 3087176

End: 3087856

Strand: Direct

Name: pgl [H]

Synonym: GBP346_A3191

Alternate gene names: 237813416

Gene position: 3087176-3087856 (Clockwise)

Preceding gene: 237813415

Following gene: 237813417

Centisome position: 75.32

GC content: 72.1

Gene sequence:

>681_bases
GTGATCGAGGTTCACGCTTTCGAAACCCCGCGCGCGCAAACCGAAGCGCTCGCGCAAGCGGTCGGCGAAGCGCTCGCGGC
CACGCTCGCGCAACGCGCGCGCGCGACGCTCGCGGTGTCGGGCGGCACGAGCCCGCGGCCGTTCCTGCAAACGCTGTCGG
GCGCCGCGCTCGACTGGCCGCGGATCGACGTGACGCTCGTCGACGACCGCTGGGTGCCCGACACCGACGACGCGAGTAAC
GCGAAGCTCGTGCGCGAGACGCTGCTGCGCAACGCGGCCGCGCACGCGCGCTTCGCGCCGCTCGTCGACCTGCGCGAGTC
GCTCGACGCGCAAATCGCCGCGCTCAACCAGAGCCCCGCGCACCCGCTGCCCGACGTCGCCGTGCTCGGCATGGGCGAGG
ACGGCCATACCGCGTCGATCTTCGCGGACGCGCCCGAATGGGACCACGCGATCGCGACGACCGAGCGCTTCGTCGGCGTC
CACCCGGGCGCGGCGCCTCATGCGCGGGTGAGCCTGTCGCTCGGCGCGCTCAAGCGCATCGGGCGCGTGTTCCTGCTGAT
CGCGGGAAGCCGCAAGCGCGCGGTGCTCGAGGCGGCCGCGGCCGCGCCGCAGAAGAACGCGATTTCGCAACTGGCCAACG
ACAAGGGGACGAAGCTCGATGTCTACTGGTGCGCAAACTAA

Upstream 100 bases:

>100_bases
AGAAGAAAACTGATGCAATGCGGCGCGCGGCTGCCGTGCGCGCGCCGCCCGATGTCCCCACGCAATTCAATCCATTCAAT
AAAGGCAGTCTGGAGGAGAA

Downstream 100 bases:

>100_bases
GGCCGCCGCGGCGAGCCAGCACGCGGACGGGCCGCGCCTATTGGCCGACGTCGGCGGCACGAACGCGCGCTTCGCGCTCG
AGACGGGCCCGGGAGAAATC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIEVHAFETPRAQTEALAQAVGEALAATLAQRARATLAVSGGTSPRPFLQTLSGAALDWPRIDVTLVDDRWVPDTDDASN
AKLVRETLLRNAAAHARFAPLVDLRESLDAQIAALNQSPAHPLPDVAVLGMGEDGHTASIFADAPEWDHAIATTERFVGV
HPGAAPHARVSLSLGALKRIGRVFLLIAGSRKRAVLEAAAAAPQKNAISQLANDKGTKLDVYWCAN

Sequences:

>Translated_226_residues
MIEVHAFETPRAQTEALAQAVGEALAATLAQRARATLAVSGGTSPRPFLQTLSGAALDWPRIDVTLVDDRWVPDTDDASN
AKLVRETLLRNAAAHARFAPLVDLRESLDAQIAALNQSPAHPLPDVAVLGMGEDGHTASIFADAPEWDHAIATTERFVGV
HPGAAPHARVSLSLGALKRIGRVFLLIAGSRKRAVLEAAAAAPQKNAISQLANDKGTKLDVYWCAN
>Mature_226_residues
MIEVHAFETPRAQTEALAQAVGEALAATLAQRARATLAVSGGTSPRPFLQTLSGAALDWPRIDVTLVDDRWVPDTDDASN
AKLVRETLLRNAAAHARFAPLVDLRESLDAQIAALNQSPAHPLPDVAVLGMGEDGHTASIFADAPEWDHAIATTERFVGV
HPGAAPHARVSLSLGALKRIGRVFLLIAGSRKRAVLEAAAAAPQKNAISQLANDKGTKLDVYWCAN

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=232, Percent_Identity=31.8965517241379, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 23925; Mature: 23925

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVHAFETPRAQTEALAQAVGEALAATLAQRARATLAVSGGTSPRPFLQTLSGAALDWP
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHCCCCCCCC
RIDVTLVDDRWVPDTDDASNAKLVRETLLRNAAAHARFAPLVDLRESLDAQIAALNQSPA
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
HPLPDVAVLGMGEDGHTASIFADAPEWDHAIATTERFVGVHPGAAPHARVSLSLGALKRI
CCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHEECCCCCCCCCEEEEHHHHHHHH
GRVFLLIAGSRKRAVLEAAAAAPQKNAISQLANDKGTKLDVYWCAN
CEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MIEVHAFETPRAQTEALAQAVGEALAATLAQRARATLAVSGGTSPRPFLQTLSGAALDWP
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHCCCCCCCC
RIDVTLVDDRWVPDTDDASNAKLVRETLLRNAAAHARFAPLVDLRESLDAQIAALNQSPA
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
HPLPDVAVLGMGEDGHTASIFADAPEWDHAIATTERFVGVHPGAAPHARVSLSLGALKRI
CCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHEECCCCCCCCCEEEEHHHHHHHH
GRVFLLIAGSRKRAVLEAAAAAPQKNAISQLANDKGTKLDVYWCAN
CEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]